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Items: 1 to 20 of 37

1.

The yin-yang of DNA damage response: roles in tumorigenesis and cellular senescence.

Li X, Xu H, Xu C, Lin M, Song X, Yi F, Feng Y, Coughlan KA, Cho WC, Kim SS, Cao L.

Int J Mol Sci. 2013 Jan 25;14(2):2431-48. doi: 10.3390/ijms14022431.

2.

DNA damage signalling guards against activated oncogenes and tumour progression.

Bartek J, Bartkova J, Lukas J.

Oncogene. 2007 Dec 10;26(56):7773-9. Review.

PMID:
18066090
3.

Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication.

Di Micco R, Fumagalli M, Cicalese A, Piccinin S, Gasparini P, Luise C, Schurra C, Garre' M, Nuciforo PG, Bensimon A, Maestro R, Pelicci PG, d'Adda di Fagagna F.

Nature. 2006 Nov 30;444(7119):638-42.

PMID:
17136094
4.

Cellular senescence in the development and treatment of cancer.

Saretzki G.

Curr Pharm Des. 2010 Jan;16(1):79-100. Review.

PMID:
20214620
5.

Monitoring DNA damage during cell senescence.

Nelson G, von Zglinicki T.

Methods Mol Biol. 2013;965:197-213. doi: 10.1007/978-1-62703-239-1_13.

PMID:
23296660
6.

Oncogene- and tumor suppressor gene-mediated suppression of cellular senescence.

Larsson LG.

Semin Cancer Biol. 2011 Dec;21(6):367-76. doi: 10.1016/j.semcancer.2011.10.005. Review.

PMID:
22037160
7.

Oxidation in the nucleotide pool, the DNA damage response and cellular senescence: Defective bricks build a defective house.

Rai P.

Mutat Res. 2010 Nov 28;703(1):71-81. doi: 10.1016/j.mrgentox.2010.07.010. Review. Erratum in: Mutat Res. 2011 Sep 18;724(1-2):88.

PMID:
20673809
8.

The Myc-evoked DNA damage response accounts for treatment resistance in primary lymphomas in vivo.

Reimann M, Loddenkemper C, Rudolph C, Schildhauer I, Teichmann B, Stein H, Schlegelberger B, Dörken B, Schmitt CA.

Blood. 2007 Oct 15;110(8):2996-3004.

9.

Tumor stroma-derived TGF-beta limits myc-driven lymphomagenesis via Suv39h1-dependent senescence.

Reimann M, Lee S, Loddenkemper C, Dörr JR, Tabor V, Aichele P, Stein H, Dörken B, Jenuwein T, Schmitt CA.

Cancer Cell. 2010 Mar 16;17(3):262-72. doi: 10.1016/j.ccr.2009.12.043.

10.

Cancer, aging and cellular senescence.

Campisi J.

In Vivo. 2000 Jan-Feb;14(1):183-8. Review.

PMID:
10757076
11.

DDR-mediated crosstalk between DNA-damaged cells and their microenvironment.

Malaquin N, Carrier-Leclerc A, Dessureault M, Rodier F.

Front Genet. 2015 Mar 12;6:94. doi: 10.3389/fgene.2015.00094. Review.

12.

Microphthalmia-associated transcription factor controls the DNA damage response and a lineage-specific senescence program in melanomas.

Giuliano S, Cheli Y, Ohanna M, Bonet C, Beuret L, Bille K, Loubat A, Hofman V, Hofman P, Ponzio G, Bahadoran P, Ballotti R, Bertolotto C.

Cancer Res. 2010 May 1;70(9):3813-22. doi: 10.1158/0008-5472.CAN-09-2913.

13.

The Yin and Yang functions of the Myc oncoprotein in cancer development and as targets for therapy.

Larsson LG, Henriksson MA.

Exp Cell Res. 2010 May 1;316(8):1429-37. doi: 10.1016/j.yexcr.2010.03.025. Review.

PMID:
20382143
14.

Heterochromatin marks HP1γ, HP1α and H3K9me3, and DNA damage response activation in human testis development and germ cell tumours.

Bartkova J, Moudry P, Hodny Z, Lukas J, Rajpert-De Meyts E, Bartek J.

Int J Androl. 2011 Aug;34(4 Pt 2):e103-13. doi: 10.1111/j.1365-2605.2010.01096.x.

PMID:
20695923
15.

α-Catulin knockdown induces senescence in cancer cells.

Fan LC, Chiang WF, Liang CH, Tsai YT, Wong TY, Chen KC, Hong TM, Chen YL.

Oncogene. 2011 Jun 9;30(23):2610-21. doi: 10.1038/onc.2010.637.

PMID:
21278790
16.

Selective tumor killing based on specific DNA-damage response deficiencies.

Biss M, Xiao W.

Cancer Biol Ther. 2012 Mar;13(5):239-46. doi: 10.4161/cbt.18921. Review.

17.
18.

Acquisition of oxidative DNA damage during senescence: the first step toward carcinogenesis?

Martien S, Abbadie C.

Ann N Y Acad Sci. 2007 Nov;1119:51-63. Review.

PMID:
18056954
19.

Understanding DNA damage response and DNA repair pathways: applications to more targeted cancer therapeutics.

Kinsella TJ.

Semin Oncol. 2009 Apr;36(2 Suppl 1):S42-51. doi: 10.1053/j.seminoncol.2009.02.004.

PMID:
19393835
20.

Crosstalk between chromatin state and DNA damage response in cellular senescence and cancer.

Sulli G, Di Micco R, d'Adda di Fagagna F.

Nat Rev Cancer. 2012 Oct;12(10):709-20. doi: 10.1038/nrc3344.

PMID:
22952011
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