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Items: 1 to 20 of 112

1.

Sorafenib induces autophagy in human myeloid dendritic cells and prolongs survival of skin allografts.

Lin JC, Huang WP, Liu CL, Lee JJ, Liu TP, Ko WC, Huang YC, Hsu ML, Wu CH, Chen YJ.

Transplantation. 2013 Mar 27;95(6):791-800. doi: 10.1097/TP.0b013e31827fac48.

PMID:
23354299
2.

Sorafenib induces autophagy and suppresses activation of human macrophage.

Lin JC, Liu CL, Lee JJ, Liu TP, Ko WC, Huang YC, Wu CH, Chen YJ.

Int Immunopharmacol. 2013 Feb;15(2):333-9. doi: 10.1016/j.intimp.2013.01.006. Epub 2013 Jan 19. Erratum in: Int Immunopharmacol. 2013 May;16(1):123. Liu, Tsan-Pai [corrected to Liu, Tsang-Pai].

PMID:
23337882
3.

Inhibition of autophagy potentiates the antitumor effect of the multikinase inhibitor sorafenib in hepatocellular carcinoma.

Shimizu S, Takehara T, Hikita H, Kodama T, Tsunematsu H, Miyagi T, Hosui A, Ishida H, Tatsumi T, Kanto T, Hiramatsu N, Fujita N, Yoshimori T, Hayashi N.

Int J Cancer. 2012 Aug 1;131(3):548-57. doi: 10.1002/ijc.26374. Epub 2011 Sep 12.

4.

Sorafenib-mediated targeting of the AAA⁺ ATPase p97/VCP leads to disruption of the secretory pathway, endoplasmic reticulum stress, and hepatocellular cancer cell death.

Yi P, Higa A, Taouji S, Bexiga MG, Marza E, Arma D, Castain C, Le Bail B, Simpson JC, Rosenbaum J, Balabaud C, Bioulac-Sage P, Blanc JF, Chevet E.

Mol Cancer Ther. 2012 Dec;11(12):2610-20. doi: 10.1158/1535-7163.MCT-12-0516. Epub 2012 Oct 5.

5.

Sorafenib-induced defective autophagy promotes cell death by necroptosis.

Kharaziha P, Chioureas D, Baltatzis G, Fonseca P, Rodriguez P, Gogvadze V, Lennartsson L, Björklund AC, Zhivotovsky B, Grandér D, Egevad L, Nilsson S, Panaretakis T.

Oncotarget. 2015 Nov 10;6(35):37066-82. doi: 10.18632/oncotarget.5797.

6.

Inhibition of doxorubicin-induced autophagy in hepatocellular carcinoma Hep3B cells by sorafenib--the role of extracellular signal-regulated kinase counteraction.

Manov I, Pollak Y, Broneshter R, Iancu TC.

FEBS J. 2011 Sep;278(18):3494-507. doi: 10.1111/j.1742-4658.2011.08271.x.

7.

Sorafenib induces autophagic cell death and apoptosis in hepatic stellate cell through the JNK and Akt signaling pathways.

Hao H, Zhang D, Shi J, Wang Y, Chen L, Guo Y, Ma J, Jiang X, Jiang H.

Anticancer Drugs. 2016 Mar;27(3):192-203. doi: 10.1097/CAD.0000000000000316.

PMID:
26629768
8.

Novel sorafenib-based structural analogues: in-vitro anticancer evaluation of t-MTUCB and t-AUCMB.

Wecksler AT, Hwang SH, Wettersten HI, Gilda JE, Patton A, Leon LJ, Carraway KL 3rd, Gomes AV, Baar K, Weiss RH, Hammock BD.

Anticancer Drugs. 2014 Apr;25(4):433-46. doi: 10.1097/CAD.0000000000000079.

9.

Inhibition of Autophagy by Chloroquine Enhances the Antitumor Efficacy of Sorafenib in Glioblastoma.

Liu X, Sun K, Wang H, Dai Y.

Cell Mol Neurobiol. 2016 Oct;36(7):1197-208. doi: 10.1007/s10571-015-0318-z. Epub 2016 Mar 14.

PMID:
26971793
10.

Sorafenib reduces hepatic infiltrated regulatory T cells in hepatocellular carcinoma patients by suppressing TGF-beta signal.

Wang Q, Yu T, Yuan Y, Zhuang H, Wang Z, Liu X, Feng M.

J Surg Oncol. 2013 Mar;107(4):422-7. doi: 10.1002/jso.23227. Epub 2012 Jul 25.

PMID:
22833259
11.

Norcantharidin modulates development of dendritic cells and prolongs skin allograft survival.

Hsieh CH, Liao HF, Kuo CD, Huang YC, Shueng PW, Hsu YP, Wang LY, Tsai TH, Chen YJ.

Transplantation. 2011 Oct 27;92(8):848-57. doi: 10.1097/TP.0b013e31822d8708.

PMID:
21876479
12.

[Multikinase inhibitors as a new approach in neovascular age-related macular degeneration (AMD) treatment: in vitro safety evaluations of axitinib, pazopanib and sorafenib for intraocular use].

Thiele S, Liegl RG, König S, Siedlecki J, Langer J, Eibl K, Haritoglou C, Kampik A, Kernt M.

Klin Monbl Augenheilkd. 2013 Mar;230(3):247-54. doi: 10.1055/s-0032-1328161. Epub 2013 Mar 18. German.

PMID:
23508753
13.

Compound C induces protective autophagy in cancer cells through AMPK inhibition-independent blockade of Akt/mTOR pathway.

Vucicevic L, Misirkic M, Janjetovic K, Vilimanovich U, Sudar E, Isenovic E, Prica M, Harhaji-Trajkovic L, Kravic-Stevovic T, Bumbasirevic V, Trajkovic V.

Autophagy. 2011 Jan;7(1):40-50. Epub 2011 Jan 1.

PMID:
20980833
14.

Sorafenib down-regulates expression of HTATIP2 to promote invasiveness and metastasis of orthotopic hepatocellular carcinoma tumors in mice.

Zhang W, Sun HC, Wang WQ, Zhang QB, Zhuang PY, Xiong YQ, Zhu XD, Xu HX, Kong LQ, Wu WZ, Wang L, Song TQ, Li Q, Tang ZY.

Gastroenterology. 2012 Dec;143(6):1641-1649.e5. doi: 10.1053/j.gastro.2012.08.032. Epub 2012 Aug 23.

PMID:
22922424
15.

Alloantigen-pulsed host dendritic cells induce T-cell regulation and prolong allograft survival in a rat model of hindlimb allotransplantation.

Kuo YR, Huang CW, Goto S, Wang CT, Hsu LW, Lin YC, Yang KD, Chen CL, Lee WP.

J Surg Res. 2009 May 15;153(2):317-25. doi: 10.1016/j.jss.2008.05.034. Epub 2008 Jun 25.

PMID:
19101689
16.

Rho-kinase-dependent pathway mediates the hepatoprotective effects of sorafenib against ischemia/reperfusion liver injury in rats with nonalcoholic steatohepatitis.

Yang YY, Huang YT, Lee TY, Chan CC, Yeh YC, Lee KC, Lin HC.

Liver Transpl. 2012 Nov;18(11):1371-83. doi: 10.1002/lt.23520.

17.

Rapamycin induces autophagy in islets: relevance in islet transplantation.

Tanemura M, Saga A, Kawamoto K, Machida T, Deguchi T, Nishida T, Sawa Y, Doki Y, Mori M, Ito T.

Transplant Proc. 2009 Jan-Feb;41(1):334-8. doi: 10.1016/j.transproceed.2008.10.032.

PMID:
19249550
18.

Targeting autophagy enhances BO-1051-induced apoptosis in human malignant glioma cells.

Chu PM, Chen LH, Chen MT, Ma HI, Su TL, Hsieh PC, Chien CS, Jiang BH, Chen YC, Lin YH, Shih YH, Tu PH, Chiou SH.

Cancer Chemother Pharmacol. 2012 Mar;69(3):621-33. doi: 10.1007/s00280-011-1747-0. Epub 2011 Sep 27.

PMID:
21947203
19.

Rationally designed aberrant kinase-targeted endogenous protein nanomedicine against oncogene mutated/amplified refractory chronic myeloid leukemia.

Retnakumari AP, Hanumanthu PL, Malarvizhi GL, Prabhu R, Sidharthan N, Thampi MV, Menon D, Mony U, Menon K, Keechilat P, Nair S, Koyakutty M.

Mol Pharm. 2012 Nov 5;9(11):3062-78. doi: 10.1021/mp300172e. Epub 2012 Oct 5.

PMID:
22971013
20.

Sorafenib prolongs liver regeneration after hepatic resection in rats.

Mollbrink A, Augsten M, Hultcrantz R, Eriksson LC, Stål P.

J Surg Res. 2013 Oct;184(2):847-54. doi: 10.1016/j.jss.2013.04.062. Epub 2013 May 18.

PMID:
23726434

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