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Items: 1 to 20 of 123

1.

Determination of tissue distribution of potent antitumor agent ureidomustin (BO-1055) by HPLC and its pharmacokinetic application in rats.

Chien SI, Yen JC, Kakadiya R, Chen CH, Lee TC, Su TL, Tsai TH.

J Chromatogr B Analyt Technol Biomed Life Sci. 2013 Feb 15;917-918:62-70. doi: 10.1016/j.jchromb.2012.12.025. Epub 2013 Jan 9.

PMID:
23353940
2.
3.

Development and validation of a highly rapid and sensitive LC-MS/MS method for determination of SZ-685C, an investigational marine anticancer agent, in rat plasma--application to a pharmacokinetic study in rats.

Chen JY, Wang XD, Zhong GP, Qin XL, Li JL, Huang ZY, Zhu X, Li MF, Huang M.

J Chromatogr B Analyt Technol Biomed Life Sci. 2011 Jul 15;879(22):2127-34. doi: 10.1016/j.jchromb.2011.05.049. Epub 2011 Jun 12.

PMID:
21703949
4.

Rapid and sensitive ultra-high-pressure liquid chromatography-tandem mass spectrometry analysis of the novel anticancer agent PR-104 and its major metabolites in human plasma: Application to a pharmacokinetic study.

Gu Y, Wilson WR.

J Chromatogr B Analyt Technol Biomed Life Sci. 2009 Oct 1;877(27):3181-6. doi: 10.1016/j.jchromb.2009.08.009. Epub 2009 Aug 13.

PMID:
19709934
5.

Quantitative determination of zolmitriptan in rat blood and cerebrospinal fluid by reversed phase HPLC-ESI-MS/MS analysis: application to in vivo preclinical pharmacokinetic study.

Dalpiaz A, Marchetti N, Cavazzini A, Pasti L, Velaga S, Gavini E, Beggiato S, Ferraro L.

J Chromatogr B Analyt Technol Biomed Life Sci. 2012 Jul 15;901:72-8. doi: 10.1016/j.jchromb.2012.06.001. Epub 2012 Jun 12.

PMID:
22743338
6.

Quantification of leonurine, a novel potential cardiovascular agent, in rat plasma by liquid chromatography-tandem mass spectrometry and its application to pharmacokinetic study in rats.

Zhu Q, Cai W, Sha X, Ma G, Zheng Y, Shi X, Zhu Y.

Biomed Chromatogr. 2012 Apr;26(4):518-23. doi: 10.1002/bmc.1699. Epub 2011 Sep 1.

PMID:
21882210
7.

Application of a liquid chromatography-tandem mass spectrometry (LC-MS/MS) method to the pharmacokinetics, tissue distribution and excretion studies of felotaxel (SHR110008) in tumor-bearing mice.

Ding Y, Lu C, Yang J, Jin X, Yang L, Wang C, Ma Z, Zhu Y, Ding L, Jia Y, Wen A.

J Chromatogr B Analyt Technol Biomed Life Sci. 2012 Mar 1;887-888:61-6. doi: 10.1016/j.jchromb.2012.01.010. Epub 2012 Jan 23.

PMID:
22309773
8.
9.

Simultaneous quantification of Polyphyllin D and Paris H, two potential antitumor active components in Paris polyphylla by liquid chromatography-tandem mass spectrometry and the application to pharmacokinetics in rats.

Wu S, Gao W, Qiu F, Man S, Fu S, Liu C.

J Chromatogr B Analyt Technol Biomed Life Sci. 2012 Sep 15;905:54-60. doi: 10.1016/j.jchromb.2012.08.002. Epub 2012 Aug 8.

PMID:
22917593
10.

A sensitive and selective liquid chromatographic tandem mass spectrometric assay for simultaneous quantification of novel trioxane antimalarials in different biomatrices using sample-pooling approach for high throughput pharmacokinetic studies.

Singh RP, Sabarinath S, Singh SK, Gupta RC.

J Chromatogr B Analyt Technol Biomed Life Sci. 2008 Mar 15;864(1-2):52-60. doi: 10.1016/j.jchromb.2008.01.054. Epub 2008 Feb 17.

PMID:
18316253
11.

Quantitative determination and pharmacokinetic study of the novel anti-Parkinson's disease candidate drug FLZ in rat brain by high performance liquid chromatography-tandem mass spectrometry.

Hou J, Qu F, Wu C, Ren Q, Zhang J.

J Pharm Biomed Anal. 2012 Jul;66:232-9. doi: 10.1016/j.jpba.2012.03.001. Epub 2012 Mar 10.

PMID:
22472186
12.

Development and validation of an high performance liquid chromatography-tandem mass spectrometry method for the determination of imatinib in rat tissues.

Bianchi F, Caffarri E, Cavalli S, Lagrasta C, Musci M, Quaini F, Savi M.

J Pharm Biomed Anal. 2013 Jan 25;73:103-7. doi: 10.1016/j.jpba.2012.05.034. Epub 2012 Jun 1.

PMID:
22709608
13.

Simultaneous determination of amlodipine and bisoprolol in rat plasma by a liquid chromatography/tandem mass spectrometry method and its application in pharmacokinetic study.

Chang H, Li J, Li J, Guan X, Sun F, Qian Z, Bi K, Fan G.

J Pharm Biomed Anal. 2012 Dec;71:104-10. doi: 10.1016/j.jpba.2012.08.012. Epub 2012 Aug 19.

PMID:
22947502
14.

Liquid chromatography-tandem mass spectrometry determination of baclofen in various biological samples and application to a pharmacokinetic study.

Kim TH, Shin S, Shin JC, Choi JH, Seo WS, Park GY, Kwon DR, Yoo SD, Lee AR, Joo SH, Min BS, Yoo WY, Shin BS.

J Chromatogr B Analyt Technol Biomed Life Sci. 2013 Nov 1;938:43-50. doi: 10.1016/j.jchromb.2013.08.030. Epub 2013 Aug 28.

PMID:
24036500
15.

Simultaneous quantification of seven plasma metabolites of sulfur mustard by ultra high performance liquid chromatography-tandem mass spectrometry.

Li C, Chen J, Liu Q, Xie J, Li H.

J Chromatogr B Analyt Technol Biomed Life Sci. 2013 Feb 15;917-918:100-7. doi: 10.1016/j.jchromb.2012.12.035. Epub 2013 Jan 9.

PMID:
23369883
16.

Quantification of henatinib maleate, a novel potent inhibitor of VEGF receptors, in rat plasma by LC-MS/MS.

Gu P, Ding Y, Sun D, Hang T, Liu W, Ding L.

Biomed Chromatogr. 2010 Apr;24(4):420-5. doi: 10.1002/bmc.1308.

PMID:
19662624
17.

Simultaneous determination of metacavir and its metabolites in rat plasma using high-performance liquid chromatography with tandem mass spectrometric detection (LC-MS/MS).

Zhang Y, Huang X, Jiang Z, Huang X, Hu Y, Zhu D, Zhang S, Wang J, Zhang L.

Biomed Chromatogr. 2012 Mar;26(3):363-70. doi: 10.1002/bmc.1667. Epub 2011 Jul 20.

PMID:
21773980
18.

LC-MS/MS method for determination of epothilone B in rat plasma and its application in pharmacokinetic study.

Lu HM, Ye M.

Arzneimittelforschung. 2012 Dec;62(12):609-13. doi: 10.1055/s-0032-1327695. Epub 2012 Oct 23.

PMID:
23093482
19.

Comparative study of A HPLC-MS assay versus an UHPLC-MS/MS for anti-tumoral alkyl lysophospholipid edelfosine determination in both biological samples and in lipid nanoparticulate systems.

Estella-Hermoso de Mendoza A, Campanero MA, Mollinedo F, Blanco-PrĂ­eto MJ.

J Chromatogr B Analyt Technol Biomed Life Sci. 2009 Dec 1;877(31):4035-41. doi: 10.1016/j.jchromb.2009.10.020. Epub 2009 Oct 24.

PMID:
19896423
20.

Plasma pharmacokinetics and tissue distribution study of cajaninstilbene acid in rats by liquid chromatography with tandem mass spectrometry.

Hua X, Fu YJ, Zu YG, Wu N, Kong Y, Li J, Peng X, Efferth T.

J Pharm Biomed Anal. 2010 Jun 5;52(2):273-9. doi: 10.1016/j.jpba.2010.01.004. Epub 2010 Jan 15.

PMID:
20116956

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