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Items: 1 to 20 of 123

1.

Endoglin haploinsufficiency promotes fibroblast accumulation during wound healing through Akt activation.

Pericacho M, Velasco S, Prieto M, Llano E, López-Novoa JM, Rodríguez-Barbero A.

PLoS One. 2013;8(1):e54687. doi: 10.1371/journal.pone.0054687. Epub 2013 Jan 17.

2.

Notoginsenoside Ft1 Promotes Fibroblast Proliferation via PI3K/Akt/mTOR Signaling Pathway and Benefits Wound Healing in Genetically Diabetic Mice.

Zhang E, Gao B, Yang L, Wu X, Wang Z.

J Pharmacol Exp Ther. 2016 Feb;356(2):324-32. doi: 10.1124/jpet.115.229369. Epub 2015 Nov 13.

3.

ILK-PI3K/AKT pathway participates in cutaneous wound contraction by regulating fibroblast migration and differentiation to myofibroblast.

Li G, Li YY, Sun JE, Lin WH, Zhou RX.

Lab Invest. 2016 Jul;96(7):741-51. doi: 10.1038/labinvest.2016.48. Epub 2016 Apr 25.

4.

Interleukin-6 stimulates Akt and p38 MAPK phosphorylation and fibroblast migration in non-diabetic but not diabetic mice.

Nishikai-Yan Shen T, Kanazawa S, Kado M, Okada K, Luo L, Hayashi A, Mizuno H, Tanaka R.

PLoS One. 2017 May 23;12(5):e0178232. doi: 10.1371/journal.pone.0178232. eCollection 2017.

5.

The mechanisms underlying fibroblast apoptosis regulated by growth factors during wound healing.

Akasaka Y, Ono I, Kamiya T, Ishikawa Y, Kinoshita T, Ishiguro S, Yokoo T, Imaizumi R, Inomata N, Fujita K, Akishima-Fukasawa Y, Uzuki M, Ito K, Ishii T.

J Pathol. 2010 Jul;221(3):285-99. doi: 10.1002/path.2710.

PMID:
20527022
6.

c-Ski promotes skin fibroblast proliferation but decreases type I collagen: implications for wound healing and scar formation.

Liu X, Li P, Chen XY, Zhou YG.

Clin Exp Dermatol. 2010 Jun;35(4):417-24. doi: 10.1111/j.1365-2230.2009.03606.x. Epub 2009 Oct 23.

PMID:
19874315
7.

[Effects of PI3K/Akt Pathway in Wound Healing Process of Mice Skin].

Gao YL, Liu CS, Zhao R, Wang LL, Li SS, Liu M, Zhang M, Jiang SK, Tian ZL, Wang M, Guan DW.

Fa Yi Xue Za Zhi. 2016 Feb;32(1):7-12. Chinese.

PMID:
27295849
8.

Impaired wound repair in adult endoglin heterozygous mice associated with lower NO bioavailability.

Pérez-Gómez E, Jerkic M, Prieto M, Del Castillo G, Martín-Villar E, Letarte M, Bernabeu C, Pérez-Barriocanal F, Quintanilla M, López-Novoa JM.

J Invest Dermatol. 2014 Jan;134(1):247-255. doi: 10.1038/jid.2013.263. Epub 2013 Jun 13.

9.

The activation of the NF-κB-JNK pathway is independent of the PI3K-Rac1-JNK pathway involved in the bFGF-regulated human fibroblast cell migration.

Xuan Y, Chi L, Tian H, Cai W, Sun C, Wang T, Zhou X, Shao M, Zhu Y, Niu C, Sun Y, Cong W, Zhu Z, Li Z, Wang Y, Jin L.

J Dermatol Sci. 2016 Apr;82(1):28-37. doi: 10.1016/j.jdermsci.2016.01.003. Epub 2016 Jan 7.

PMID:
26829882
10.

NGF accelerates cutaneous wound healing by promoting the migration of dermal fibroblasts via the PI3K/Akt-Rac1-JNK and ERK pathways.

Chen JC, Lin BB, Hu HW, Lin C, Jin WY, Zhang FB, Zhu YA, Lu CJ, Wei XJ, Chen RJ.

Biomed Res Int. 2014;2014:547187. doi: 10.1155/2014/547187. Epub 2014 May 21.

11.

The stimulatory effects of Stewartia koreana extract on the proliferation and migration of fibroblasts and the wound healing activity of the extract in mice.

Lee TH, Lee GW, Park KH, Mohamed MA, Bang MH, Baek YS, Son Y, Chung DK, Baek NI, Kim J.

Int J Mol Med. 2014 Jul;34(1):145-52. doi: 10.3892/ijmm.2014.1753. Epub 2014 Apr 24.

PMID:
24789471
12.

Impaired wound healing results from the dysfunction of the Akt/mTOR pathway in diabetic rats.

Huang H, Cui W, Qiu W, Zhu M, Zhao R, Zeng D, Dong C, Wang X, Guo W, Xing W, Li X, Li L, Tan Y, Wu X, Chen L, Fu X, Luo D, Xu X.

J Dermatol Sci. 2015 Sep;79(3):241-51. doi: 10.1016/j.jdermsci.2015.06.002. Epub 2015 Jun 10.

PMID:
26091964
13.

Control of fibroblast fibronectin expression and alternative splicing via the PI3K/Akt/mTOR pathway.

White ES, Sagana RL, Booth AJ, Yan M, Cornett AM, Bloomheart CA, Tsui JL, Wilke CA, Moore BB, Ritzenthaler JD, Roman J, Muro AF.

Exp Cell Res. 2010 Oct 1;316(16):2644-53. doi: 10.1016/j.yexcr.2010.06.028. Epub 2010 Jul 13.

14.

Endostatin stimulates proliferation and migration of adult rat cardiac fibroblasts through PI3K/Akt pathway.

Okada M, Oba Y, Yamawaki H.

Eur J Pharmacol. 2015 Mar 5;750:20-6. doi: 10.1016/j.ejphar.2015.01.019. Epub 2015 Jan 22.

PMID:
25620135
15.

Altered dermal fibroblast behavior in a collagen V haploinsufficient murine model of classic Ehlers-Danlos syndrome.

DeNigris J, Yao Q, Birk EK, Birk DE.

Connect Tissue Res. 2016;57(1):1-9. doi: 10.3109/03008207.2015.1081901. Epub 2015 Dec 29.

16.

bFGF Promotes the Migration of Human Dermal Fibroblasts under Diabetic Conditions through Reactive Oxygen Species Production via the PI3K/Akt-Rac1- JNK Pathways.

Shi H, Cheng Y, Ye J, Cai P, Zhang J, Li R, Yang Y, Wang Z, Zhang H, Lin C, Lu X, Jiang L, Hu A, Zhu X, Zeng Q, Fu X, Li X, Xiao J.

Int J Biol Sci. 2015 Jun 1;11(7):845-59. doi: 10.7150/ijbs.11921. eCollection 2015.

17.

Effects of TRAP-1-like protein (TLP) gene on collagen synthesis induced by TGF-β/Smad signaling in human dermal fibroblasts.

Wang X, Qian Y, Jin R, Wo Y, Chen J, Wang C, Wang D.

PLoS One. 2013;8(2):e55899. doi: 10.1371/journal.pone.0055899. Epub 2013 Feb 13.

18.

Agonistic analogs of growth hormone releasing hormone (GHRH) promote wound healing by stimulating the proliferation and survival of human dermal fibroblasts through ERK and AKT pathways.

Cui T, Jimenez JJ, Block NL, Badiavas EV, Rodriguez-Menocal L, Vila Granda A, Cai R, Sha W, Zarandi M, Perez R, Schally AV.

Oncotarget. 2016 Aug 16;7(33):52661-52672. doi: 10.18632/oncotarget.11024.

19.

Up-regulation of thrombospondin-2 in Akt1-null mice contributes to compromised tissue repair due to abnormalities in fibroblast function.

Bancroft T, Bouaouina M, Roberts S, Lee M, Calderwood DA, Schwartz M, Simons M, Sessa WC, Kyriakides TR.

J Biol Chem. 2015 Jan 2;290(1):409-22. doi: 10.1074/jbc.M114.618421. Epub 2014 Nov 11.

20.

ROS constitute a convergence nexus in the development of IGF1 resistance and impaired wound healing in a rat model of type 2 diabetes.

Bitar MS, Al-Mulla F.

Dis Model Mech. 2012 May;5(3):375-88. doi: 10.1242/dmm.007872. Epub 2012 Feb 23.

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