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Items: 1 to 20 of 80

1.

Disruption of the cereblon gene enhances hepatic AMPK activity and prevents high-fat diet-induced obesity and insulin resistance in mice.

Lee KM, Yang SJ, Kim YD, Choi YD, Nam JH, Choi CS, Choi HS, Park CS.

Diabetes. 2013 Jun;62(6):1855-64. doi: 10.2337/db12-1030. Epub 2013 Jan 24.

2.

Functional modulation of AMP-activated protein kinase by cereblon.

Lee KM, Jo S, Kim H, Lee J, Park CS.

Biochim Biophys Acta. 2011 Mar;1813(3):448-55. doi: 10.1016/j.bbamcr.2011.01.005. Epub 2011 Jan 11.

3.

Ablation of cereblon attenuates myocardial ischemia-reperfusion injury.

Kim J, Lee KM, Park CS, Park WJ.

Biochem Biophys Res Commun. 2014 May 16;447(4):649-54. doi: 10.1016/j.bbrc.2014.04.061. Epub 2014 Apr 19.

PMID:
24755080
4.

Functional effects of a pathogenic mutation in Cereblon (CRBN) on the regulation of protein synthesis via the AMPK-mTOR cascade.

Lee KM, Yang SJ, Choi JH, Park CS.

J Biol Chem. 2014 Aug 22;289(34):23343-52. doi: 10.1074/jbc.M113.523423. Epub 2014 Jul 3.

5.

AMP-activated protein kinase α2 subunit is required for the preservation of hepatic insulin sensitivity by n-3 polyunsaturated fatty acids.

Jelenik T, Rossmeisl M, Kuda O, Jilkova ZM, Medrikova D, Kus V, Hensler M, Janovska P, Miksik I, Baranowski M, Gorski J, Hébrard S, Jensen TE, Flachs P, Hawley S, Viollet B, Kopecky J.

Diabetes. 2010 Nov;59(11):2737-46. doi: 10.2337/db09-1716. Epub 2010 Aug 6.

6.

Distinct Time Course of the Decrease in Hepatic AMP-Activated Protein Kinase and Akt Phosphorylation in Mice Fed a High Fat Diet.

Shiwa M, Yoneda M, Okubo H, Ohno H, Kobuke K, Monzen Y, Kishimoto R, Nakatsu Y, Asano T, Kohno N.

PLoS One. 2015 Aug 12;10(8):e0135554. doi: 10.1371/journal.pone.0135554. eCollection 2015.

7.

AMPK and insulin action--responses to ageing and high fat diet.

Frøsig C, Jensen TE, Jeppesen J, Pehmøller C, Treebak JT, Maarbjerg SJ, Kristensen JM, Sylow L, Alsted TJ, Schjerling P, Kiens B, Wojtaszewski JF, Richter EA.

PLoS One. 2013 May 6;8(5):e62338. doi: 10.1371/journal.pone.0062338. Print 2013.

8.

Ping-tang Recipe () improves insulin resistance and attenuates hepatic steatosis in high-fat diet-induced obese rats.

Yang SY, Zhao NJ, Li XJ, Zhang HJ, Chen KJ, Li CD.

Chin J Integr Med. 2012 Apr;18(4):262-8. doi: 10.1007/s11655-012-1023-0. Epub 2012 Mar 30.

PMID:
22457136
9.

Interleukin-18 activates skeletal muscle AMPK and reduces weight gain and insulin resistance in mice.

Lindegaard B, Matthews VB, Brandt C, Hojman P, Allen TL, Estevez E, Watt MJ, Bruce CR, Mortensen OH, Syberg S, Rudnicka C, Abildgaard J, Pilegaard H, Hidalgo J, Ditlevsen S, Alsted TJ, Madsen AN, Pedersen BK, Febbraio MA.

Diabetes. 2013 Sep;62(9):3064-74. doi: 10.2337/db12-1095. Epub 2013 May 13.

10.

Piperine reverses high fat diet-induced hepatic steatosis and insulin resistance in mice.

Choi S, Choi Y, Choi Y, Kim S, Jang J, Park T.

Food Chem. 2013 Dec 15;141(4):3627-35. doi: 10.1016/j.foodchem.2013.06.028. Epub 2013 Jun 17.

PMID:
23993530
11.

AMP-activated protein kinase α1 protects against diet-induced insulin resistance and obesity.

Zhang W, Zhang X, Wang H, Guo X, Li H, Wang Y, Xu X, Tan L, Mashek MT, Zhang C, Chen Y, Mashek DG, Foretz M, Zhu C, Zhou H, Liu X, Viollet B, Wu C, Huo Y.

Diabetes. 2012 Dec;61(12):3114-25. doi: 10.2337/db11-1373. Epub 2012 Jul 24. Retraction in: Diabetes. 2013 Mar;62(3):998.

12.

Dietary folic acid activates AMPK and improves insulin resistance and hepatic inflammation in dietary rodent models of the metabolic syndrome.

Buettner R, Bettermann I, Hechtl C, Gäbele E, Hellerbrand C, Schölmerich J, Bollheimer LC.

Horm Metab Res. 2010 Oct;42(11):769-74. doi: 10.1055/s-0030-1263122. Epub 2010 Aug 27.

PMID:
20803414
13.

Muscle-selective knockout of AMPKα2 does not exacerbate diet-induced obesity probably related to altered myokines expression.

Chen T, Li Z, Zhang Y, Feng F, Wang X, Wang X, Shen QW.

Biochem Biophys Res Commun. 2015 Mar 13;458(3):449-55. doi: 10.1016/j.bbrc.2015.01.075. Epub 2015 Jan 28.

PMID:
25637528
14.

Inhibition of cereblon by fenofibrate ameliorates alcoholic liver disease by enhancing AMPK.

Kim YD, Lee KM, Hwang SL, Chang HW, Kim KJ, Harris RA, Choi HS, Choi WS, Lee SE, Park CS.

Biochim Biophys Acta. 2015 Dec;1852(12):2662-70. doi: 10.1016/j.bbadis.2015.09.014. Epub 2015 Sep 26.

15.

Whole body deletion of AMP-activated protein kinase {beta}2 reduces muscle AMPK activity and exercise capacity.

Steinberg GR, O'Neill HM, Dzamko NL, Galic S, Naim T, Koopman R, Jørgensen SB, Honeyman J, Hewitt K, Chen ZP, Schertzer JD, Scott JW, Koentgen F, Lynch GS, Watt MJ, van Denderen BJ, Campbell DJ, Kemp BE.

J Biol Chem. 2010 Nov 26;285(48):37198-209. doi: 10.1074/jbc.M110.102434. Epub 2010 Sep 20.

16.

Naringin ameliorates metabolic syndrome by activating AMP-activated protein kinase in mice fed a high-fat diet.

Pu P, Gao DM, Mohamed S, Chen J, Zhang J, Zhou XY, Zhou NJ, Xie J, Jiang H.

Arch Biochem Biophys. 2012 Feb 1;518(1):61-70. doi: 10.1016/j.abb.2011.11.026. Epub 2011 Dec 16.

PMID:
22198281
17.

Berberine inhibits mouse insulin gene promoter through activation of AMP activated protein kinase and may exert beneficial effect on pancreatic β-cell.

Shen N, Huan Y, Shen ZF.

Eur J Pharmacol. 2012 Nov 5;694(1-3):120-6. doi: 10.1016/j.ejphar.2012.07.052. Epub 2012 Aug 29.

PMID:
22955013
18.

Effects of lipoic acid on AMPK and adiponectin in adipose tissue of low- and high-fat-fed rats.

Prieto-Hontoria PL, Pérez-Matute P, Fernández-Galilea M, Alfredo Martínez J, Moreno-Aliaga MJ.

Eur J Nutr. 2013 Mar;52(2):779-87. doi: 10.1007/s00394-012-0384-7. Epub 2012 Jun 5.

PMID:
22664981
19.

Acute activation of central GLP-1 receptors enhances hepatic insulin action and insulin secretion in high-fat-fed, insulin resistant mice.

Burmeister MA, Ferre T, Ayala JE, King EM, Holt RM, Ayala JE.

Am J Physiol Endocrinol Metab. 2012 Feb 1;302(3):E334-43. doi: 10.1152/ajpendo.00409.2011. Epub 2011 Nov 15.

20.

Genetic disruption of protein phosphatase 5 in mice prevents high-fat diet feeding-induced weight gain.

Grankvist N, Honkanen RE, Sjöholm Å, Ortsäter H.

FEBS Lett. 2013 Nov 29;587(23):3869-74. doi: 10.1016/j.febslet.2013.10.022. Epub 2013 Oct 26.

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