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Items: 1 to 20 of 157

1.

Store-independent Orai1/3 channels activated by intracrine leukotriene C4: role in neointimal hyperplasia.

González-Cobos JC, Zhang X, Zhang W, Ruhle B, Motiani RK, Schindl R, Muik M, Spinelli AM, Bisaillon JM, Shinde AV, Fahrner M, Singer HA, Matrougui K, Barroso M, Romanin C, Trebak M.

Circ Res. 2013 Mar 29;112(7):1013-25. doi: 10.1161/CIRCRESAHA.111.300220. Epub 2013 Jan 24.

2.

Mechanisms of STIM1 activation of store-independent leukotriene C4-regulated Ca2+ channels.

Zhang X, González-Cobos JC, Schindl R, Muik M, Ruhle B, Motiani RK, Bisaillon JM, Zhang W, Fahrner M, Barroso M, Matrougui K, Romanin C, Trebak M.

Mol Cell Biol. 2013 Sep;33(18):3715-23. doi: 10.1128/MCB.00554-13. Epub 2013 Jul 22.

3.

Leukotriene-C4 synthase, a critical enzyme in the activation of store-independent Orai1/Orai3 channels, is required for neointimal hyperplasia.

Zhang W, Zhang X, González-Cobos JC, Stolwijk JA, Matrougui K, Trebak M.

J Biol Chem. 2015 Feb 20;290(8):5015-27. doi: 10.1074/jbc.M114.625822. Epub 2014 Dec 24.

4.

Essential role for STIM1/Orai1-mediated calcium influx in PDGF-induced smooth muscle migration.

Bisaillon JM, Motiani RK, Gonzalez-Cobos JC, Potier M, Halligan KE, Alzawahra WF, Barroso M, Singer HA, Jourd'heuil D, Trebak M.

Am J Physiol Cell Physiol. 2010 May;298(5):C993-1005. doi: 10.1152/ajpcell.00325.2009. Epub 2010 Jan 27.

5.

Orai1-mediated I (CRAC) is essential for neointima formation after vascular injury.

Zhang W, Halligan KE, Zhang X, Bisaillon JM, Gonzalez-Cobos JC, Motiani RK, Hu G, Vincent PA, Zhou J, Barroso M, Singer HA, Matrougui K, Trebak M.

Circ Res. 2011 Aug 19;109(5):534-42. doi: 10.1161/CIRCRESAHA.111.246777. Epub 2011 Jul 7.

6.

Complex role of STIM1 in the activation of store-independent Orai1/3 channels.

Zhang X, Zhang W, González-Cobos JC, Jardin I, Romanin C, Matrougui K, Trebak M.

J Gen Physiol. 2014 Mar;143(3):345-59. doi: 10.1085/jgp.201311084.

7.

Airway smooth muscle STIM1 and Orai1 are upregulated in asthmatic mice and mediate PDGF-activated SOCE, CRAC currents, proliferation, and migration.

Spinelli AM, González-Cobos JC, Zhang X, Motiani RK, Rowan S, Zhang W, Garrett J, Vincent PA, Matrougui K, Singer HA, Trebak M.

Pflugers Arch. 2012 Nov;464(5):481-92. doi: 10.1007/s00424-012-1160-5. Epub 2012 Sep 27.

8.

Evidence for STIM1- and Orai1-dependent store-operated calcium influx through ICRAC in vascular smooth muscle cells: role in proliferation and migration.

Potier M, Gonzalez JC, Motiani RK, Abdullaev IF, Bisaillon JM, Singer HA, Trebak M.

FASEB J. 2009 Aug;23(8):2425-37. doi: 10.1096/fj.09-131128. Epub 2009 Apr 13.

9.

Both Orai1 and Orai3 are essential components of the arachidonate-regulated Ca2+-selective (ARC) channels.

Mignen O, Thompson JL, Shuttleworth TJ.

J Physiol. 2008 Jan 1;586(1):185-95. Epub 2007 Nov 8.

10.

Emergence of Orai3 activity during cardiac hypertrophy.

Saliba Y, Keck M, Marchand A, Atassi F, Ouillé A, Cazorla O, Trebak M, Pavoine C, Lacampagne A, Hulot JS, Farès N, Fauconnier J, Lompré AM.

Cardiovasc Res. 2015 Mar 1;105(3):248-59. doi: 10.1093/cvr/cvu207. Epub 2014 Sep 11.

11.

Orai1, a critical component of store-operated Ca2+ entry, is functionally associated with Na+/Ca2+ exchanger and plasma membrane Ca2+ pump in proliferating human arterial myocytes.

Baryshnikov SG, Pulina MV, Zulian A, Linde CI, Golovina VA.

Am J Physiol Cell Physiol. 2009 Nov;297(5):C1103-12. doi: 10.1152/ajpcell.00283.2009. Epub 2009 Aug 12.

12.

Stim1- and Orai1-mediated store-operated calcium entry is critical for angiotensin II-induced vascular smooth muscle cell proliferation.

Guo RW, Yang LX, Li MQ, Pan XH, Liu B, Deng YL.

Cardiovasc Res. 2012 Feb 1;93(2):360-70. doi: 10.1093/cvr/cvr307. Epub 2011 Nov 22.

PMID:
22108917
13.

Emerging roles of Orai3 in pathophysiology.

Motiani RK, Stolwijk JA, Newton RL, Zhang X, Trebak M.

Channels (Austin). 2013 Sep-Oct;7(5):392-401. doi: 10.4161/chan.24960. Epub 2013 May 21. Review.

14.
15.

The many faces of Orai.

Welsh DG.

Circ Res. 2013 Mar 29;112(7):983-4. doi: 10.1161/CIRCRESAHA.113.301052. No abstract available.

16.

Emerging roles for native Orai Ca2+ channels in cardiovascular disease.

Ruhle B, Trebak M.

Curr Top Membr. 2013;71:209-35. doi: 10.1016/B978-0-12-407870-3.00009-3. Review.

17.

Calcium inhibition and calcium potentiation of Orai1, Orai2, and Orai3 calcium release-activated calcium channels.

DeHaven WI, Smyth JT, Boyles RR, Putney JW Jr.

J Biol Chem. 2007 Jun 15;282(24):17548-56. Epub 2007 Apr 23.

18.

The ryanodine receptor agonist 4-chloro-3-ethylphenol blocks ORAI store-operated channels.

Zeng B, Chen GL, Daskoulidou N, Xu SZ.

Br J Pharmacol. 2014 Mar;171(5):1250-9. doi: 10.1111/bph.12528.

19.

An essential role for stromal interaction molecule 1 in neointima formation following arterial injury.

Guo RW, Wang H, Gao P, Li MQ, Zeng CY, Yu Y, Chen JF, Song MB, Shi YK, Huang L.

Cardiovasc Res. 2009 Mar 1;81(4):660-8. doi: 10.1093/cvr/cvn338. Epub 2008 Dec 3.

PMID:
19052075
20.

STIM/Orai signalling complexes in vascular smooth muscle.

Trebak M.

J Physiol. 2012 Sep 1;590(17):4201-8. doi: 10.1113/jphysiol.2012.233353. Epub 2012 May 28. Review.

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