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Items: 1 to 20 of 99


Nodal promotes aggressive phenotype via Snail-mediated epithelial-mesenchymal transition in murine melanoma.

Fang R, Zhang G, Guo Q, Ning F, Wang H, Cai S, Du J.

Cancer Lett. 2013 Jun 1;333(1):66-75. doi: 10.1016/j.canlet.2013.01.014. Epub 2013 Jan 22.


Snail regulated by PKC/GSK-3β pathway is crucial for EGF-induced epithelial-mesenchymal transition (EMT) of cancer cells.

Liu ZC, Chen XH, Song HX, Wang HS, Zhang G, Wang H, Chen DY, Fang R, Liu H, Cai SH, Du J.

Cell Tissue Res. 2014 Nov;358(2):491-502. doi: 10.1007/s00441-014-1953-2. Epub 2014 Aug 16.


Stabilization of Snail through AKT/GSK-3β signaling pathway is required for TNF-α-induced epithelial-mesenchymal transition in prostate cancer PC3 cells.

Wang H, Fang R, Wang XF, Zhang F, Chen DY, Zhou B, Wang HS, Cai SH, Du J.

Eur J Pharmacol. 2013 Aug 15;714(1-3):48-55. doi: 10.1016/j.ejphar.2013.05.046. Epub 2013 Jun 11.


AKT/GSK-3β regulates stability and transcription of snail which is crucial for bFGF-induced epithelial-mesenchymal transition of prostate cancer cells.

Liu ZC, Wang HS, Zhang G, Liu H, Chen XH, Zhang F, Chen DY, Cai SH, Du J.

Biochim Biophys Acta. 2014 Oct;1840(10):3096-105. doi: 10.1016/j.bbagen.2014.07.018. Epub 2014 Aug 1.


Downregulation of tumor suppressing STF cDNA 3 promotes epithelial-mesenchymal transition and tumor metastasis of osteosarcoma by the Wnt/GSK-3β/β-catenin/Snail signaling pathway.

Lv YF, Dai H, Yan GN, Meng G, Zhang X, Guo QN.

Cancer Lett. 2016 Apr 10;373(2):164-73. doi: 10.1016/j.canlet.2016.01.046. Epub 2016 Feb 1.


Epithelial-mesenchymal transition (EMT) induced by TNF-α requires AKT/GSK-3β-mediated stabilization of snail in colorectal cancer.

Wang H, Wang HS, Zhou BH, Li CL, Zhang F, Wang XF, Zhang G, Bu XZ, Cai SH, Du J.

PLoS One. 2013;8(2):e56664. doi: 10.1371/journal.pone.0056664. Epub 2013 Feb 19.


Endogenous Nodal promotes melanoma undergoing epithelial-mesenchymal transition via Snail and Slug in vitro and in vivo.

Guo Q, Ning F, Fang R, Wang HS, Zhang G, Quan MY, Cai SH, Du J.

Am J Cancer Res. 2015 May 15;5(6):2098-112. eCollection 2015.


Acquisition of EMT phenotype in the gefitinib-resistant cells of a head and neck squamous cell carcinoma cell line through Akt/GSK-3β/snail signalling pathway.

Maseki S, Ijichi K, Tanaka H, Fujii M, Hasegawa Y, Ogawa T, Murakami S, Kondo E, Nakanishi H.

Br J Cancer. 2012 Mar 13;106(6):1196-204. doi: 10.1038/bjc.2012.24. Epub 2012 Feb 7.


Bmi-1 promotes invasion and metastasis, and its elevated expression is correlated with an advanced stage of breast cancer.

Guo BH, Feng Y, Zhang R, Xu LH, Li MZ, Kung HF, Song LB, Zeng MS.

Mol Cancer. 2011 Jan 28;10(1):10. doi: 10.1186/1476-4598-10-10.


Maelstrom promotes hepatocellular carcinoma metastasis by inducing epithelial-mesenchymal transition by way of Akt/GSK-3β/Snail signaling.

Liu L, Dai Y, Chen J, Zeng T, Li Y, Chen L, Zhu YH, Li J, Li Y, Ma S, Xie D, Yuan YF, Guan XY.

Hepatology. 2014 Feb;59(2):531-43. doi: 10.1002/hep.26677. Epub 2013 Dec 23. Erratum in: Hepatology. 2016 Mar;63(3):1064.


Involvement of Pin1 induction in epithelial-mesenchymal transition of tamoxifen-resistant breast cancer cells.

Kim MR, Choi HK, Cho KB, Kim HS, Kang KW.

Cancer Sci. 2009 Oct;100(10):1834-41. doi: 10.1111/j.1349-7006.2009.01260.x. Epub 2009 Jul 24.


Valproic acid (VPA) promotes the epithelial mesenchymal transition of hepatocarcinoma cells via transcriptional and post-transcriptional up regulation of Snail.

Wu L, Feng H, Hu J, Tian X, Zhang C.

Biomed Pharmacother. 2016 Dec;84:1029-1035. doi: 10.1016/j.biopha.2016.10.023. Epub 2016 Oct 18.


Endothelin-1 promotes epithelial-to-mesenchymal transition in human ovarian cancer cells.

Rosanò L, Spinella F, Di Castro V, Nicotra MR, Dedhar S, de Herreros AG, Natali PG, Bagnato A.

Cancer Res. 2005 Dec 15;65(24):11649-57.


CXCR2/CXCL5 axis contributes to epithelial-mesenchymal transition of HCC cells through activating PI3K/Akt/GSK-3β/Snail signaling.

Zhou SL, Zhou ZJ, Hu ZQ, Li X, Huang XW, Wang Z, Fan J, Dai Z, Zhou J.

Cancer Lett. 2015 Mar 28;358(2):124-35. doi: 10.1016/j.canlet.2014.11.044. Epub 2014 Nov 24.


Histone deacetylase inhibitor valproic acid (VPA) promotes the epithelial mesenchymal transition of colorectal cancer cells via up regulation of Snail.

Feng J, Cen J, Li J, Zhao R, Zhu C, Wang Z, Xie J, Tang W.

Cell Adh Migr. 2015;9(6):495-501. doi: 10.1080/19336918.2015.1112486.


Glycogen synthase kinase-3 beta regulates Snail and β-catenin expression during Fas-induced epithelial-mesenchymal transition in gastrointestinal cancer.

Zheng H, Li W, Wang Y, Liu Z, Cai Y, Xie T, Shi M, Wang Z, Jiang B.

Eur J Cancer. 2013 Aug;49(12):2734-46. doi: 10.1016/j.ejca.2013.03.014. Epub 2013 Apr 9.


Acquisition of epithelial-mesenchymal transition phenotype and cancer stem cell-like properties in cisplatin-resistant lung cancer cells through AKT/β-catenin/Snail signaling pathway.

Wang H, Zhang G, Zhang H, Zhang F, Zhou B, Ning F, Wang HS, Cai SH, Du J.

Eur J Pharmacol. 2014 Jan 15;723:156-66. doi: 10.1016/j.ejphar.2013.12.004. Epub 2013 Dec 12.


Activation of snail and EMT-like signaling via the IKKαβ/NF-κB pathway in Apicidin-resistant HA22T hepatocellular carcinoma cells.

Tu CC, Cheng LH, Hsu HH, Chen LM, Lin YM, Chen MC, Lee NH, Tsai FJ, Huang CY, Wu WJ.

Chin J Physiol. 2013 Dec 31;56(6):326-33. doi: 10.4077/CJP.2013.BAB158.


GSK-3β and vitamin D receptor are involved in β-catenin and snail signaling in high glucose-induced epithelial-mesenchymal transition of mouse podocytes.

Guo J, Xia N, Yang L, Zhou S, Zhang Q, Qiao Y, Liu Z.

Cell Physiol Biochem. 2014;33(4):1087-96. doi: 10.1159/000358678. Epub 2014 Apr 9.

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