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Items: 1 to 20 of 322

1.

Thyroid hormone-responsive SPOT 14 homolog promotes hepatic lipogenesis, and its expression is regulated by liver X receptor α through a sterol regulatory element-binding protein 1c-dependent mechanism in mice.

Wu J, Wang C, Li S, Li S, Wang W, Li J, Chi Y, Yang H, Kong X, Zhou Y, Dong C, Wang F, Xu G, Yang J, Gustafsson JÅ, Guan Y.

Hepatology. 2013 Aug;58(2):617-28. doi: 10.1002/hep.26272.

PMID:
23348573
2.

Cross-talk between peroxisome proliferator-activated receptor (PPAR) alpha and liver X receptor (LXR) in nutritional regulation of fatty acid metabolism. I. PPARs suppress sterol regulatory element binding protein-1c promoter through inhibition of LXR signaling.

Yoshikawa T, Ide T, Shimano H, Yahagi N, Amemiya-Kudo M, Matsuzaka T, Yatoh S, Kitamine T, Okazaki H, Tamura Y, Sekiya M, Takahashi A, Hasty AH, Sato R, Sone H, Osuga J, Ishibashi S, Yamada N.

Mol Endocrinol. 2003 Jul;17(7):1240-54.

PMID:
12730331
3.

Ursodeoxycholic acid inhibits liver X receptor α-mediated hepatic lipogenesis via induction of the nuclear corepressor SMILE.

Lee JM, Gang GT, Kim DK, Kim YD, Koo SH, Lee CH, Choi HS.

J Biol Chem. 2014 Jan 10;289(2):1079-91. doi: 10.1074/jbc.M113.491522.

4.

Resveratrol inhibits LXRα-dependent hepatic lipogenesis through novel antioxidant Sestrin2 gene induction.

Jin SH, Yang JH, Shin BY, Seo K, Shin SM, Cho IJ, Ki SH.

Toxicol Appl Pharmacol. 2013 Aug 15;271(1):95-105. doi: 10.1016/j.taap.2013.04.023.

PMID:
23651738
6.
7.

Cilostazol inhibits insulin-stimulated expression of sterol regulatory binding protein-1c via inhibition of LXR and Sp1.

Jung YA, Kim HK, Bae KH, Seo HY, Kim HS, Jang BK, Jung GS, Lee IK, Kim MK, Park KG.

Exp Mol Med. 2014 Jan 24;46:e73. doi: 10.1038/emm.2013.143.

8.

Diminished hepatic response to fasting/refeeding and liver X receptor agonists in mice with selective deficiency of sterol regulatory element-binding protein-1c.

Liang G, Yang J, Horton JD, Hammer RE, Goldstein JL, Brown MS.

J Biol Chem. 2002 Mar 15;277(11):9520-8.

PMID:
11782483
10.

Cross-talk between peroxisome proliferator-activated receptor (PPAR) alpha and liver X receptor (LXR) in nutritional regulation of fatty acid metabolism. II. LXRs suppress lipid degradation gene promoters through inhibition of PPAR signaling.

Ide T, Shimano H, Yoshikawa T, Yahagi N, Amemiya-Kudo M, Matsuzaka T, Nakakuki M, Yatoh S, Iizuka Y, Tomita S, Ohashi K, Takahashi A, Sone H, Gotoda T, Osuga J, Ishibashi S, Yamada N.

Mol Endocrinol. 2003 Jul;17(7):1255-67.

PMID:
12730332
11.

Combination of honokiol and magnolol inhibits hepatic steatosis through AMPK-SREBP-1 c pathway.

Lee JH, Jung JY, Jang EJ, Jegal KH, Moon SY, Ku SK, Kang SH, Cho IJ, Park SJ, Lee JR, Zhao RJ, Kim SC, Kim YW.

Exp Biol Med (Maywood). 2015 Apr;240(4):508-18. doi: 10.1177/1535370214547123.

12.

Thyrotropin increases hepatic triglyceride content through upregulation of SREBP-1c activity.

Yan F, Wang Q, Lu M, Chen W, Song Y, Jing F, Guan Y, Wang L, Lin Y, Bo T, Zhang J, Wang T, Xin W, Yu C, Guan Q, Zhou X, Gao L, Xu C, Zhao J.

J Hepatol. 2014 Dec;61(6):1358-64. doi: 10.1016/j.jhep.2014.06.037.

PMID:
25016220
13.

Mechanism of AMPK suppression of LXR-dependent Srebp-1c transcription.

Yap F, Craddock L, Yang J.

Int J Biol Sci. 2011;7(5):645-50.

15.

Hepatic TRAP80 selectively regulates lipogenic activity of liver X receptor.

Kim GH, Oh GS, Yoon J, Lee GG, Lee KU, Kim SW.

J Clin Invest. 2015 Jan;125(1):183-93. doi: 10.1172/JCI73615.

16.

Regulation of hepatic fatty acid elongase 5 by LXRalpha-SREBP-1c.

Qin Y, Dalen KT, Gustafsson JA, Nebb HI.

Biochim Biophys Acta. 2009 Feb;1791(2):140-7. doi: 10.1016/j.bbalip.2008.12.003.

PMID:
19136075
17.

Polyunsaturated fatty acids suppress sterol regulatory element-binding protein 1c promoter activity by inhibition of liver X receptor (LXR) binding to LXR response elements.

Yoshikawa T, Shimano H, Yahagi N, Ide T, Amemiya-Kudo M, Matsuzaka T, Nakakuki M, Tomita S, Okazaki H, Tamura Y, Iizuka Y, Ohashi K, Takahashi A, Sone H, Osuga Ji J, Gotoda T, Ishibashi S, Yamada N.

J Biol Chem. 2002 Jan 18;277(3):1705-11.

PMID:
11694526
18.

The role of liver X receptor-alpha in the fatty acid regulation of hepatic gene expression.

Pawar A, Botolin D, Mangelsdorf DJ, Jump DB.

J Biol Chem. 2003 Oct 17;278(42):40736-43.

PMID:
12917410
19.

A functional cross-talk between liver X receptor-α and constitutive androstane receptor links lipogenesis and xenobiotic responses.

Zhai Y, Wada T, Zhang B, Khadem S, Ren S, Kuruba R, Li S, Xie W.

Mol Pharmacol. 2010 Oct;78(4):666-74. doi: 10.1124/mol.110.064618.

20.

Hepatic differentiated embryo-chondrocyte-expressed gene 1 (Dec1) inhibits sterol regulatory element-binding protein-1c (Srebp-1c) expression and alleviates fatty liver phenotype.

Shen L, Cui A, Xue Y, Cui Y, Dong X, Gao Y, Yang H, Fang F, Chang Y.

J Biol Chem. 2014 Aug 22;289(34):23332-42. doi: 10.1074/jbc.M113.526343.

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