Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 235

1.

Superoxide anion production by NADPH oxidase plays a major role in erectile dysfunction in middle-aged rats: prevention by antioxidant therapy.

Silva FH, Mónica FZ, Báu FR, Brugnerotto AF, Priviero FB, Toque HA, Antunes E.

J Sex Med. 2013 Apr;10(4):960-71. doi: 10.1111/jsm.12063. Epub 2013 Jan 24.

PMID:
23347406
2.

Oxidative stress associated with middle aging leads to sympathetic hyperactivity and downregulation of soluble guanylyl cyclase in corpus cavernosum.

Silva FH, Lanaro C, Leiria LO, Rodrigues RL, Davel AP, Claudino MA, Toque HA, Antunes E.

Am J Physiol Heart Circ Physiol. 2014 Nov 15;307(10):H1393-400. doi: 10.1152/ajpheart.00708.2013. Epub 2014 Sep 12.

PMID:
25217652
3.

Chronic inhibition of nitric-oxide synthase induces hypertension and erectile dysfunction in the rat that is not reversed by sildenafil.

Gur S, Kadowitz PJ, Gurkan L, Chandra S, Dewitt SY, Harbin A, Sikka SC, Agrawal KC, Hellstrom WJ.

BJU Int. 2010 Jul;106(1):78-83. doi: 10.1111/j.1464-410X.2009.09104.x. Epub 2009 Dec 11.

4.

Hypercholesterolemia-induced erectile dysfunction: endothelial nitric oxide synthase (eNOS) uncoupling in the mouse penis by NAD(P)H oxidase.

Musicki B, Liu T, Lagoda GA, Strong TD, Sezen SF, Johnson JM, Burnett AL.

J Sex Med. 2010 Sep;7(9):3023-32. doi: 10.1111/j.1743-6109.2010.01880.x.

5.

Apocynin improves erectile function in diabetic rats through regulation of NADPH oxidase expression.

Li M, Zhuan L, Wang T, Rao K, Yang J, Yang J, Quan W, Liu J, Ye Z.

J Sex Med. 2012 Dec;9(12):3041-50. doi: 10.1111/j.1743-6109.2012.02960.x. Epub 2012 Oct 22.

PMID:
23088159
6.

Nebivolol dilates human penile arteries and reverses erectile dysfunction in diabetic rats through enhancement of nitric oxide signaling.

Angulo J, Wright HM, Cuevas P, González-Corrochano R, Fernández A, Cuevas B, La Fuente JM, Gupta S, Sáenz de Tejada I.

J Sex Med. 2010 Aug;7(8):2681-97. doi: 10.1111/j.1743-6109.2010.01710.x. Epub 2010 Feb 26.

PMID:
20214719
7.

The effect of sildenafil on corpus cavernosal smooth muscle relaxation and cyclic GMP formation in the diabetic rabbit.

Thompson CS, Mumtaz FH, Khan MA, Wallis RM, Mikhailidis DP, Morgan RJ, Angelini GD, Jeremy JY.

Eur J Pharmacol. 2001 Aug 3;425(1):57-64.

PMID:
11672575
8.

Nebivolol potentiates the efficacy of PDE5 inhibitors to relax corpus cavernosum and penile arteries from diabetic patients by enhancing the NO/cGMP pathway.

Martínez-Salamanca JI, La Fuente JM, Cardoso J, Fernández A, Cuevas P, Wright HM, Angulo J.

J Sex Med. 2014 May;11(5):1182-92.

PMID:
24877179
9.
10.

Resveratrol and sildenafil synergistically improve diabetes-associated erectile dysfunction in streptozotocin-induced diabetic rats.

Bai Y, An R.

Life Sci. 2015 Aug 15;135:43-8. doi: 10.1016/j.lfs.2015.04.020. Epub 2015 May 23.

PMID:
26006044
11.

Upregulation of gp91phox subunit of NAD(P)H oxidase contributes to erectile dysfunction caused by long-term nitric oxide inhibition in rats: reversion by regular physical training.

Claudino MA, Franco-Penteado CF, Priviero FB, Camargo EA, Teixeira SA, Muscará MN, De Nucci G, Zanesco A, Antunes E.

Urology. 2010 Apr;75(4):961-7. doi: 10.1016/j.urology.2009.05.098. Epub 2009 Dec 4.

PMID:
19962729
12.

Role of neural NO synthase (nNOS) uncoupling in the dysfunctional nitrergic vasorelaxation of penile arteries from insulin-resistant obese Zucker rats.

Sánchez A, Contreras C, Martínez MP, Climent B, Benedito S, García-Sacristán A, Hernández M, Prieto D.

PLoS One. 2012;7(4):e36027. doi: 10.1371/journal.pone.0036027. Epub 2012 Apr 23.

13.
14.

Ca2+ -activated K+ channel (KCa) stimulation improves relaxant capacity of PDE5 inhibitors in human penile arteries and recovers the reduced efficacy of PDE5 inhibition in diabetic erectile dysfunction.

González-Corrochano R, La Fuente J, Cuevas P, Fernández A, Chen M, Sáenz de Tejada I, Angulo J.

Br J Pharmacol. 2013 May;169(2):449-61. doi: 10.1111/bph.12143.

15.

Sildenafil inhibits superoxide formation and prevents endothelial dysfunction in a mouse model of secondhand smoke induced erectile dysfunction.

Bivalacqua TJ, Sussan TE, Gebska MA, Strong TD, Berkowitz DE, Biswal S, Burnett AL, Champion HC.

J Urol. 2009 Feb;181(2):899-906. doi: 10.1016/j.juro.2008.10.062. Epub 2008 Dec 17.

16.

Effect of combination endothelial nitric oxide synthase gene therapy and sildenafil on erectile function in diabetic rats.

Bivalacqua TJ, Usta MF, Champion HC, Leungwattanakij S, Dabisch PA, McNamara DB, Kadowitz PJ, Hellstrom WJ.

Int J Impot Res. 2004 Feb;16(1):21-9.

PMID:
14963467
17.

Comparison of sildenafil with strontium fructose diphosphate in improving erectile dysfunction against upregulated cavernosal NADPH oxidase, protein kinase Cε, and endothelin system in diabetic rats.

Xu M, Tang YQ, Dai DZ, Zheng YF, Cheng YS, Zhang Q, Dai Y.

J Pharm Pharmacol. 2012 Feb;64(2):244-51. doi: 10.1111/j.2042-7158.2011.01390.x. Epub 2011 Nov 18.

PMID:
22221100
18.
19.

Testosterone restores diabetes-induced erectile dysfunction and sildenafil responsiveness in two distinct animal models of chemical diabetes.

Zhang XH, Filippi S, Morelli A, Vignozzi L, Luconi M, Donati S, Forti G, Maggi M.

J Sex Med. 2006 Mar;3(2):253-64; discussion 264-5, author reply 265-6. Erratum in: J Sex Med. 2006 May;3(3):573.

PMID:
16490018
20.

Beneficial effect of the soluble guanylyl cyclase stimulator BAY 41-2272 on impaired penile erection in db/db-/- type II diabetic and obese mice.

Nunes KP, Teixeira CE, Priviero FB, Toque HA, Webb RC.

J Pharmacol Exp Ther. 2015 May;353(2):330-9. doi: 10.1124/jpet.114.220970. Epub 2015 Mar 4.

Supplemental Content

Support Center