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Items: 1 to 20 of 82

1.

Direct evidence for the adaptive role of copy number variation on antifolate susceptibility in Plasmodium falciparum.

Heinberg A, Siu E, Stern C, Lawrence EA, Ferdig MT, Deitsch KW, Kirkman LA.

Mol Microbiol. 2013 May;88(4):702-12. doi: 10.1111/mmi.12162. Epub 2013 Apr 24.

2.

Adaptive copy number evolution in malaria parasites.

Nair S, Miller B, Barends M, Jaidee A, Patel J, Mayxay M, Newton P, Nosten F, Ferdig MT, Anderson TJ.

PLoS Genet. 2008 Oct;4(10):e1000243. doi: 10.1371/journal.pgen.1000243. Epub 2008 Oct 31.

3.

The molecular basis of antifolate resistance in Plasmodium falciparum: looking beyond point mutations.

Heinberg A, Kirkman L.

Ann N Y Acad Sci. 2015 Apr;1342:10-8. doi: 10.1111/nyas.12662. Epub 2015 Feb 18. Review.

4.

Origin of robustness in generating drug-resistant malaria parasites.

K├╝mpornsin K, Modchang C, Heinberg A, Ekland EH, Jirawatcharadech P, Chobson P, Suwanakitti N, Chaotheing S, Wilairat P, Deitsch KW, Kamchonwongpaisan S, Fidock DA, Kirkman LA, Yuthavong Y, Chookajorn T.

Mol Biol Evol. 2014 Jul;31(7):1649-60. doi: 10.1093/molbev/msu140. Epub 2014 Apr 16.

5.

Similar trends of pyrimethamine resistance-associated mutations in Plasmodium vivax and P. falciparum.

Alam MT, Bora H, Bharti PK, Saifi MA, Das MK, Dev V, Kumar A, Singh N, Dash AP, Das B, Wajihullah, Sharma YD.

Antimicrob Agents Chemother. 2007 Mar;51(3):857-63. Epub 2006 Dec 28.

6.

Antifolate drug resistance and point mutations in Plasmodium falciparum in Kenya.

Khan B, Omar S, Kanyara JN, Warren-Perry M, Nyalwidhe J, Peterson DS, Wellems T, Kaniaru S, Gitonga J, Mulaa FJ, Koech DK.

Trans R Soc Trop Med Hyg. 1997 Jul-Aug;91(4):456-60.

PMID:
9373654
7.

Selection of drug resistant mutants from random library of Plasmodium falciparum dihydrofolate reductase in Plasmodium berghei model.

Tipsuwan W, Srichairatanakool S, Kamchonwongpaisan S, Yuthavong Y, Uthaipibull C.

Malar J. 2011 May 10;10:119. doi: 10.1186/1475-2875-10-119.

9.

Escalating Plasmodium falciparum antifolate drug resistance mutations in Macha, rural Zambia.

Mkulama MA, Chishimba S, Sikalima J, Rouse P, Thuma PE, Mharakurwa S.

Malar J. 2008 May 21;7:87. doi: 10.1186/1475-2875-7-87.

10.

Mutations associated with sulfadoxine-pyrimethamine and chlorproguanil resistance in Plasmodium falciparum isolates from Blantyre, Malawi.

Alker AP, Mwapasa V, Purfield A, Rogerson SJ, Molyneux ME, Kamwendo DD, Tadesse E, Chaluluka E, Meshnick SR.

Antimicrob Agents Chemother. 2005 Sep;49(9):3919-21.

11.

Detection of copy number variation and single nucleotide polymorphisms in genes involved in drug resistance and other phenotypic traits in P. falciparum clinical isolates collected from Uganda.

Kiwuwa MS, Byarugaba J, Wahlgren M, Kironde F.

Acta Trop. 2013 Mar;125(3):269-75. doi: 10.1016/j.actatropica.2012.11.013. Epub 2012 Dec 7.

PMID:
23220229
12.

Use of a semi-nested PCR diagnosis test to evaluate antifolate resistance of Plasmodium falciparum isolates.

Eldin de Pecoulas P, Abdallah B, Dje MK, Basco LK, le Bras J, Mazabraud A.

Mol Cell Probes. 1995 Dec;9(6):391-7.

PMID:
8808309
13.
14.

Novel alleles of Plasmodium falciparum dhfr that confer resistance to chlorcycloguanil.

Hunt SY, Rezvani BB, Sibley CH.

Mol Biochem Parasitol. 2005 Jan;139(1):25-32.

PMID:
15610816
16.

The F423Y mutation in the pfmdr2 gene and mutations N51I, C59R, and S108N in the pfdhfr gene are independently associated with pyrimethamine resistance in Plasmodium falciparum isolates.

Briolant S, Bogreau H, Gil M, Bouchiba H, Baret E, Amalvict R, Rogier C, Pradines B.

Antimicrob Agents Chemother. 2012 May;56(5):2750-2. doi: 10.1128/AAC.05618-11. Epub 2012 Feb 6.

17.

Antifolate-resistant mutants of Plasmodium falciparum dihydrofolate reductase.

Sirawaraporn W, Sathitkul T, Sirawaraporn R, Yuthavong Y, Santi DV.

Proc Natl Acad Sci U S A. 1997 Feb 18;94(4):1124-9.

19.
20.

Biochemical and functional characterization of Plasmodium falciparum GTP cyclohydrolase I.

K├╝mpornsin K, Kotanan N, Chobson P, Kochakarn T, Jirawatcharadech P, Jaru-ampornpan P, Yuthavong Y, Chookajorn T.

Malar J. 2014 Apr 19;13:150. doi: 10.1186/1475-2875-13-150.

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