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Items: 1 to 20 of 199

1.

Selection of nanobodies that target human neonatal Fc receptor.

Andersen JT, Gonzalez-Pajuelo M, Foss S, Landsverk OJ, Pinto D, Szyroki A, de Haard HJ, Saunders M, Vanlandschoot P, Sandlie I.

Sci Rep. 2013;3:1118. doi: 10.1038/srep01118. Epub 2013 Jan 23.

2.

Qualification of a homogeneous cell-based neonatal Fc receptor (FcRn) binding assay and its application to studies on Fc functionality of IgG-based therapeutics.

Mathur A, Arora T, Liu L, Crouse-Zeineddini J, Mukku V.

J Immunol Methods. 2013 Apr 30;390(1-2):81-91. doi: 10.1016/j.jim.2013.01.011. Epub 2013 Feb 4.

PMID:
23384837
3.

The immunologic functions of the neonatal Fc receptor for IgG.

Rath T, Kuo TT, Baker K, Qiao SW, Kobayashi K, Yoshida M, Roopenian D, Fiebiger E, Lencer WI, Blumberg RS.

J Clin Immunol. 2013 Jan;33 Suppl 1:S9-17. doi: 10.1007/s10875-012-9768-y. Epub 2012 Sep 5. Review.

4.

Albumin binding to FcRn: distinct from the FcRn-IgG interaction.

Chaudhury C, Brooks CL, Carter DC, Robinson JM, Anderson CL.

Biochemistry. 2006 Apr 18;45(15):4983-90.

PMID:
16605266
5.

Characterization of the rabbit neonatal Fc receptor (FcRn) and analyzing the immunophenotype of the transgenic rabbits that overexpresses FcRn.

Catunda Lemos AP, Cervenak J, Bender B, Hoffmann OI, Baranyi M, Kerekes A, Farkas A, Bosze Z, Hiripi L, Kacskovics I.

PLoS One. 2012;7(1):e28869. doi: 10.1371/journal.pone.0028869. Epub 2012 Jan 11.

6.

Contribution of FcRn binding to intestinal uptake of IgG in suckling rat pups and human FcRn-transgenic mice.

Kliwinski C, Cooper PR, Perkinson R, Mabus JR, Tam SH, Wilkinson TM, Giles-Komar J, Scallon B, Powers GD, Hornby PJ.

Am J Physiol Gastrointest Liver Physiol. 2013 Feb 1;304(3):G262-70. doi: 10.1152/ajpgi.00340.2012. Epub 2012 Dec 6.

7.

Are endosomal trafficking parameters better targets for improving mAb pharmacokinetics than FcRn binding affinity?

Gurbaxani B, Dostalek M, Gardner I.

Mol Immunol. 2013 Dec;56(4):660-74. doi: 10.1016/j.molimm.2013.05.008. Epub 2013 Aug 2. Review.

PMID:
23917469
8.

Monoclonal antibodies with identical Fc sequences can bind to FcRn differentially with pharmacokinetic consequences.

Wang W, Lu P, Fang Y, Hamuro L, Pittman T, Carr B, Hochman J, Prueksaritanont T.

Drug Metab Dispos. 2011 Sep;39(9):1469-77. doi: 10.1124/dmd.111.039453. Epub 2011 May 24.

9.

Neonatal Fc receptor for IgG (FcRn) regulates cross-presentation of IgG immune complexes by CD8-CD11b+ dendritic cells.

Baker K, Qiao SW, Kuo TT, Aveson VG, Platzer B, Andersen JT, Sandlie I, Chen Z, de Haar C, Lencer WI, Fiebiger E, Blumberg RS.

Proc Natl Acad Sci U S A. 2011 Jun 14;108(24):9927-32. doi: 10.1073/pnas.1019037108. Epub 2011 May 31.

10.

Immune and non-immune functions of the (not so) neonatal Fc receptor, FcRn.

Baker K, Qiao SW, Kuo T, Kobayashi K, Yoshida M, Lencer WI, Blumberg RS.

Semin Immunopathol. 2009 Jul;31(2):223-36. doi: 10.1007/s00281-009-0160-9. Epub 2009 Jun 3. Review.

11.

Transfer of IgG in the female genital tract by MHC class I-related neonatal Fc receptor (FcRn) confers protective immunity to vaginal infection.

Li Z, Palaniyandi S, Zeng R, Tuo W, Roopenian DC, Zhu X.

Proc Natl Acad Sci U S A. 2011 Mar 15;108(11):4388-93. doi: 10.1073/pnas.1012861108. Epub 2011 Feb 28.

12.

N-Glycan Moieties in Neonatal Fc Receptor Determine Steady-state Membrane Distribution and Directional Transport of IgG.

Kuo TT, de Muinck EJ, Claypool SM, Yoshida M, Nagaishi T, Aveson VG, Lencer WI, Blumberg RS.

J Biol Chem. 2009 Mar 27;284(13):8292-300. doi: 10.1074/jbc.M805877200. Epub 2009 Jan 21.

13.

Transcytosis and catabolism of antibody.

Ghetie V, Ward ES.

Immunol Res. 2002;25(2):97-113. Review.

PMID:
11999172
14.

Neonatal Fc receptor (FcRn): a novel target for therapeutic antibodies and antibody engineering.

Wang Y, Tian Z, Thirumalai D, Zhang X.

J Drug Target. 2014 May;22(4):269-78. doi: 10.3109/1061186X.2013.875030. Epub 2014 Jan 9. Review.

PMID:
24404896
15.

The Neonatal Fc receptor (FcRn) enhances human immunodeficiency virus type 1 (HIV-1) transcytosis across epithelial cells.

Gupta S, Gach JS, Becerra JC, Phan TB, Pudney J, Moldoveanu Z, Joseph SB, Landucci G, Supnet MJ, Ping LH, Corti D, Moldt B, Hel Z, Lanzavecchia A, Ruprecht RM, Burton DR, Mestecky J, Anderson DJ, Forthal DN.

PLoS Pathog. 2013;9(11):e1003776. doi: 10.1371/journal.ppat.1003776. Epub 2013 Nov 21. Erratum in: PLoS Pathog. 2013 Nov;9(11). doi:10.1371/annotation/31430955-703b-484a-96eb-e180f917d683.

16.

Field flow fractionation for assessing neonatal Fc receptor and Fcγ receptor binding to monoclonal antibodies in solution.

Pollastrini J, Dillon TM, Bondarenko P, Chou RY.

Anal Biochem. 2011 Jul 1;414(1):88-98. doi: 10.1016/j.ab.2011.03.001. Epub 2011 Mar 6.

PMID:
21385563
17.

Importance of neonatal FcR in regulating the serum half-life of therapeutic proteins containing the Fc domain of human IgG1: a comparative study of the affinity of monoclonal antibodies and Fc-fusion proteins to human neonatal FcR.

Suzuki T, Ishii-Watabe A, Tada M, Kobayashi T, Kanayasu-Toyoda T, Kawanishi T, Yamaguchi T.

J Immunol. 2010 Feb 15;184(4):1968-76. doi: 10.4049/jimmunol.0903296. Epub 2010 Jan 18.

18.

Maternofetal transplacental transport of recombinant IgG antibodies lacking effector functions.

Mathiesen L, Nielsen LK, Andersen JT, Grevys A, Sandlie I, Michaelsen TE, Hedegaard M, Knudsen LE, Dziegiel MH.

Blood. 2013 Aug 15;122(7):1174-81. doi: 10.1182/blood-2012-12-473843. Epub 2013 Jul 10.

19.

The neonatal Fc receptor (FcRn) binds independently to both sites of the IgG homodimer with identical affinity.

Abdiche YN, Yeung YA, Chaparro-Riggers J, Barman I, Strop P, Chin SM, Pham A, Bolton G, McDonough D, Lindquist K, Pons J, Rajpal A.

MAbs. 2015;7(2):331-43. doi: 10.1080/19420862.2015.1008353.

20.

Neonatal Fc receptor for IgG (FcRn) expressed in the gastric epithelium regulates bacterial infection in mice.

Ben Suleiman Y, Yoshida M, Nishiumi S, Tanaka H, Mimura T, Nobutani K, Yamamoto K, Takenaka M, Aoganghua A, Miki I, Ota H, Takahashi S, Matsui H, Nakamura M, Blumberg RS, Azuma T.

Mucosal Immunol. 2012 Jan;5(1):87-98. doi: 10.1038/mi.2011.53. Epub 2011 Nov 16.

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