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Items: 1 to 20 of 97

1.

A Hyperactive Transposase Promotes Persistent Gene Transfer of a piggyBac DNA Transposon.

Burnight ER, Staber JM, Korsakov P, Li X, Brett BT, Scheetz TE, Craig NL, McCray PB Jr.

Mol Ther Nucleic Acids. 2012 Oct 16;1:e50. doi: 10.1038/mtna.2012.12.

2.

A hyperactive piggyBac transposase for mammalian applications.

Yusa K, Zhou L, Li MA, Bradley A, Craig NL.

Proc Natl Acad Sci U S A. 2011 Jan 25;108(4):1531-6. doi: 10.1073/pnas.1008322108. Epub 2011 Jan 4.

3.

Hyperactive piggyBac gene transfer in human cells and in vivo.

Doherty JE, Huye LE, Yusa K, Zhou L, Craig NL, Wilson MH.

Hum Gene Ther. 2012 Mar;23(3):311-20. doi: 10.1089/hum.2011.138. Epub 2011 Dec 14.

4.

Hybrid nonviral/viral vector systems for improved piggyBac DNA transposon in vivo delivery.

Cooney AL, Singh BK, Sinn PL.

Mol Ther. 2015 Apr;23(4):667-74. doi: 10.1038/mt.2014.254. Epub 2015 Jan 5.

5.

piggyBac transposon system modification of primary human T cells.

Saha S, Nakazawa Y, Huye LE, Doherty JE, Galvan DL, Rooney CM, Wilson MH.

J Vis Exp. 2012 Nov 5;(69):e4235. doi: 10.3791/4235.

6.

Hyperactive Himar1 transposase mediates transposition in cell culture and enhances gene expression in vivo.

Keravala A, Liu D, Lechman ER, Wolfe D, Nash JA, Lampe DJ, Robbins PD.

Hum Gene Ther. 2006 Oct;17(10):1006-18.

PMID:
16989604
7.

Modeling correction of severe urea cycle defects in the growing murine liver using a hybrid recombinant adeno-associated virus/piggyBac transposase gene delivery system.

Cunningham SC, Siew SM, Hallwirth CV, Bolitho C, Sasaki N, Garg G, Michael IP, Hetherington NA, Carpenter K, de Alencastro G, Nagy A, Alexander IE.

Hepatology. 2015 Aug;62(2):417-28. doi: 10.1002/hep.27842. Epub 2015 May 23.

PMID:
26011400
8.

Hyperactive PiggyBac Transposons for Sustained and Robust Liver-targeted Gene Therapy.

Di Matteo M, Samara-Kuko E, Ward NJ, Waddingon SN, McVey JH, Chuah MK, VandenDriessche T.

Mol Ther. 2014 Sep;22(9):1614-1624. doi: 10.1038/mt.2014.131. Epub 2016 Dec 6.

PMID:
28153205
9.

Vector modifications to eliminate transposase expression following piggyBac-mediated transgenesis.

Chakraborty S, Ji H, Chen J, Gersbach CA, Leong KW.

Sci Rep. 2014 Dec 10;4:7403. doi: 10.1038/srep07403.

10.

PiggyBac transposon-mediated gene transfer in human cells.

Wilson MH, Coates CJ, George AL Jr.

Mol Ther. 2007 Jan;15(1):139-45.

11.

In Vitro Synthesis, Delivery, and Bioavailability of Exogenous mRNA in Gene Transfer Mediated by PiggyBac Transposition.

Bire S, Ishac N, Rouleux-Bonnin F.

Methods Mol Biol. 2016;1428:187-217. doi: 10.1007/978-1-4939-3625-0_13.

PMID:
27236801
12.

Sustained high level transgene expression in mammalian cells mediated by the optimized piggyBac transposon system.

Chen X, Cui J, Yan Z, Zhang H, Chen X, Wang N, Shah P, Deng F, Zhao C, Geng N, Li M, Denduluri SK, Haydon RC, Luu HH, Reid RR, He TC.

Genes Dis. 2015 Mar;2(1):96-105.

13.

Hyperactive piggyBac transposons for sustained and robust liver-targeted gene therapy.

Di Matteo M, Samara-Kuko E, Ward NJ, Waddington SN, McVey JH, Chuah MK, VandenDriessche T.

Mol Ther. 2014 Sep;22(9):1614-24. doi: 10.1038/mt.2014.131. Epub 2014 Jul 18. Erratum in: Mol Ther. 2014 Nov;22(11):2013. Waddingon, Simon N [corrected to Waddington, Simon N]. Mol Ther. 2015 Oct;23(10):1671.

14.

Optimization of the piggyBac transposon using mRNA and insulators: toward a more reliable gene delivery system.

Bire S, Ley D, Casteret S, Mermod N, Bigot Y, Rouleux-Bonnin F.

PLoS One. 2013 Dec 3;8(12):e82559. doi: 10.1371/journal.pone.0082559. eCollection 2013.

15.

Using chimeric piggyBac transposase to achieve directed interplasmid transposition in silkworm Bombyx mori and fruit fly Drosophila cells.

Wang N, Jiang CY, Jiang MX, Zhang CX, Cheng JA.

J Zhejiang Univ Sci B. 2010 Sep;11(9):728-34. doi: 10.1631/jzus.B1000139.

16.

IPB7 transposase behavior in Drosophila melanogaster and Aedes aegypti.

Wright JA, Smith RC, Li X, Craig NL, Atkinson PW.

Insect Biochem Mol Biol. 2013 Oct;43(10):899-906. doi: 10.1016/j.ibmb.2013.06.009. Epub 2013 Jul 5.

17.

piggyBac transposase tools for genome engineering.

Li X, Burnight ER, Cooney AL, Malani N, Brady T, Sander JD, Staber J, Wheelan SJ, Joung JK, McCray PB Jr, Bushman FD, Sinn PL, Craig NL.

Proc Natl Acad Sci U S A. 2013 Jun 18;110(25):E2279-87. doi: 10.1073/pnas.1305987110. Epub 2013 May 30.

18.

Hyperactive transposase mutants of the Sleeping Beauty transposon.

Baus J, Liu L, Heggestad AD, Sanz S, Fletcher BS.

Mol Ther. 2005 Dec;12(6):1148-56. Epub 2005 Sep 8.

19.

Exogenous mRNA delivery and bioavailability in gene transfer mediated by piggyBac transposition.

Bire S, Gosset D, Jégot G, Midoux P, Pichon C, Rouleux-Bonnin F.

BMC Biotechnol. 2013 Sep 26;13:75. doi: 10.1186/1472-6750-13-75.

20.

Stable gene transfer and expression in cord blood-derived CD34+ hematopoietic stem and progenitor cells by a hyperactive Sleeping Beauty transposon system.

Xue X, Huang X, Nodland SE, Mátés L, Ma L, Izsvák Z, Ivics Z, LeBien TW, McIvor RS, Wagner JE, Zhou X.

Blood. 2009 Aug 13;114(7):1319-30. doi: 10.1182/blood-2009-03-210005. Epub 2009 May 4.

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