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Early growth response 3 (Egr3) is highly over-expressed in non-relapsing prostate cancer but not in relapsing prostate cancer.

Pio R, Jia Z, Baron VT, Mercola D; UCI NCI SPECS Consortium of the Strategic Partners for the Evaluation of Cancer Signatures-Prostate Cancer.

PLoS One. 2013;8(1):e54096. doi: 10.1371/journal.pone.0054096. Epub 2013 Jan 14.


Early Growth Response 3 regulates genes of inflammation and directly activates IL6 and IL8 expression in prostate cancer.

Baron VT, Pio R, Jia Z, Mercola D.

Br J Cancer. 2015 Feb 17;112(4):755-64. doi: 10.1038/bjc.2014.622. Epub 2015 Jan 29.


Decreased EGR3 expression is related to poor prognosis in patients with gastric cancer.

Liao F, Ji MY, Shen L, Qiu S, Guo XF, Dong WG.

J Mol Histol. 2013 Aug;44(4):463-8. doi: 10.1007/s10735-013-9493-8. Epub 2013 Mar 5.


TREM-1 and DAP12 expression in monocytes of patients with severe psychiatric disorders. EGR3, ATF3 and PU.1 as important transcription factors.

Weigelt K, Carvalho LA, Drexhage RC, Wijkhuijs A, de Wit H, van Beveren NJ, Birkenhäger TK, Bergink V, Drexhage HA.

Brain Behav Immun. 2011 Aug;25(6):1162-9. doi: 10.1016/j.bbi.2011.03.006. Epub 2011 Mar 21.


Expression of early growth response genes in human prostate cancer.

Eid MA, Kumar MV, Iczkowski KA, Bostwick DG, Tindall DJ.

Cancer Res. 1998 Jun 1;58(11):2461-8.


Genetic analysis of the calcineurin pathway identifies members of the EGR gene family, specifically EGR3, as potential susceptibility candidates in schizophrenia.

Yamada K, Gerber DJ, Iwayama Y, Ohnishi T, Ohba H, Toyota T, Aruga J, Minabe Y, Tonegawa S, Yoshikawa T.

Proc Natl Acad Sci U S A. 2007 Feb 20;104(8):2815-20. Epub 2007 Feb 20.


EGR3, a novel member of the Egr family of genes encoding immediate-early transcription factors.

Patwardhan S, Gashler A, Siegel MG, Chang LC, Joseph LJ, Shows TB, Le Beau MM, Sukhatme VP.

Oncogene. 1991 Jun;6(6):917-28.


Transcription factor EGR3 is involved in the estrogen-signaling pathway in breast cancer cells.

Inoue A, Omoto Y, Yamaguchi Y, Kiyama R, Hayashi SI.

J Mol Endocrinol. 2004 Jun;32(3):649-61.


Early growth responsive gene 3 in human breast carcinoma: a regulator of estrogen-meditated invasion and a potent prognostic factor.

Suzuki T, Inoue A, Miki Y, Moriya T, Akahira J, Ishida T, Hirakawa H, Yamaguchi Y, Hayashi S, Sasano H.

Endocr Relat Cancer. 2007 Jun;14(2):279-92.


Increased heparanase expression is caused by promoter hypomethylation and up-regulation of transcriptional factor early growth response-1 in human prostate cancer.

Ogishima T, Shiina H, Breault JE, Tabatabai L, Bassett WW, Enokida H, Li LC, Kawakami T, Urakami S, Ribeiro-Filho LA, Terashima M, Fujime M, Igawa M, Dahiya R.

Clin Cancer Res. 2005 Feb 1;11(3):1028-36.


[Loss of expression and mechanism of early growth response gene-3 in human oral squamous carcinoma].

Li Y, Wen Y, Zhou JX, Zhang ZT.

Zhonghua Yi Xue Za Zhi. 2013 Aug 27;93(32):2549-52. Chinese.


Tissue expression of neu differentiation factor/heregulin and its receptor complex in prostate cancer and its biologic effects on prostate cancer cells in vitro.

Lyne JC, Melhem MF, Finley GG, Wen D, Liu N, Deng DH, Salup R.

Cancer J Sci Am. 1997 Jan-Feb;3(1):21-30.


Redundant role for early growth response transcriptional regulators in thymocyte differentiation and survival.

Carter JH, Lefebvre JM, Wiest DL, Tourtellotte WG.

J Immunol. 2007 Jun 1;178(11):6796-805.


The cytoskeleton differentially localizes the early growth response gene-1 protein in cancer and benign cells of the prostate.

Mora GR, Olivier KR, Cheville JC, Mitchell RF Jr, Lingle WL, Tindall DJ.

Mol Cancer Res. 2004 Feb;2(2):115-28.


Analysis of gene expression in prostate cancer epithelial and interstitial stromal cells using laser capture microdissection.

Gregg JL, Brown KE, Mintz EM, Piontkivska H, Fraizer GC.

BMC Cancer. 2010 Apr 28;10:165. doi: 10.1186/1471-2407-10-165.


Regulation of human prostate-specific G-protein coupled receptor, PSGR, by two distinct promoters and growth factors.

Weng J, Ma W, Mitchell D, Zhang J, Liu M.

J Cell Biochem. 2005 Dec 1;96(5):1034-48.


Bombesin regulates cyclin D1 expression through the early growth response protein Egr-1 in prostate cancer cells.

Xiao D, Chinnappan D, Pestell R, Albanese C, Weber HC.

Cancer Res. 2005 Nov 1;65(21):9934-42.

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