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Green tea polyphenols reduced fat deposits in high fat-fed rats via erk1/2-PPARγ-adiponectin pathway.

Tian C, Ye X, Zhang R, Long J, Ren W, Ding S, Liao D, Jin X, Wu H, Xu S, Ying C.

PLoS One. 2013;8(1):e53796. doi: 10.1371/journal.pone.0053796. Epub 2013 Jan 15. Erratum in: PLoS One. 2013;8(9). doi:10.1371/annotation/83355f31-f12d-4b8e-9310-b60d11e37482.


Long term intake of 0.1% ethanol decreases serum adiponectin by suppressing PPARγ expression via p38 MAPK pathway.

Tian C, Jin X, Ye X, Wu H, Ren W, Zhang R, Long J, Ying C.

Food Chem Toxicol. 2014 Mar;65:329-34. doi: 10.1016/j.fct.2014.01.007. Epub 2014 Jan 9.


Green tea, black tea, and oolong tea polyphenols reduce visceral fat and inflammation in mice fed high-fat, high-sucrose obesogenic diets.

Heber D, Zhang Y, Yang J, Ma JE, Henning SM, Li Z.

J Nutr. 2014 Sep;144(9):1385-93. doi: 10.3945/jn.114.191007. Epub 2014 Jul 16.


Green tea polyphenols benefits body composition and improves bone quality in long-term high-fat diet-induced obese rats.

Shen CL, Cao JJ, Dagda RY, Chanjaplammootil S, Lu C, Chyu MC, Gao W, Wang JS, Yeh JK.

Nutr Res. 2012 Jun;32(6):448-57. doi: 10.1016/j.nutres.2012.05.001. Epub 2012 Jun 8.


Tea polyphenols alleviate high fat and high glucose-induced endothelial hyperpermeability by attenuating ROS production via NADPH oxidase pathway.

Zuo X, Tian C, Zhao N, Ren W, Meng Y, Jin X, Zhang Y, Ding S, Ying C, Ye X.

BMC Res Notes. 2014 Mar 2;7:120. doi: 10.1186/1756-0500-7-120.


Green tea polyphenols down-regulate caveolin-1 expression via ERK1/2 and p38MAPK in endothelial cells.

Li Y, Ying C, Zuo X, Yi H, Yi W, Meng Y, Ikeda K, Ye X, Yamori Y, Sun X.

J Nutr Biochem. 2009 Dec;20(12):1021-7. doi: 10.1016/j.jnutbio.2008.12.001. Epub 2009 Feb 5.


Parallel down-regulation of FOXO1, PPARγ and adiponectin mRNA expression in visceral adipose tissue of class III obese individuals.

Hammes TO, Costa Cdos S, Rohden F, Margis R, de Almeida JC, Padoin AV, Mottin CC, Guaragna RM.

Obes Facts. 2012;5(3):452-9. doi: 10.1159/000339574. Epub 2012 Jun 30.


Topical application of capsaicin reduces visceral adipose fat by affecting adipokine levels in high-fat diet-induced obese mice.

Lee GR, Shin MK, Yoon DJ, Kim AR, Yu R, Park NH, Han IS.

Obesity (Silver Spring). 2013 Jan;21(1):115-22. doi: 10.1002/oby.20246.


Histidine supplementation alleviates inflammation in the adipose tissue of high-fat diet-induced obese rats via the NF-κB- and PPARγ-involved pathways.

Sun X, Feng R, Li Y, Lin S, Zhang W, Li Y, Sun C, Li S.

Br J Nutr. 2014 Aug 28;112(4):477-85. doi: 10.1017/S0007114514001056. Epub 2014 May 15.


Formula diet is effective for the reduction and differentiation of visceral adipose tissue in Zucker fatty rats.

Yamaguchi T, Miyashita Y, Saiki A, Watanabe F, Watanabe H, Shirai K.

J Atheroscler Thromb. 2012;19(2):127-36. Epub 2011 Nov 21.


Phosphorylation of extracellular signal-regulated kinase (ERK)-1/2 Is associated with the downregulation of peroxisome proliferator-activated receptor (PPAR)-γ during polymicrobial sepsis.

Kaplan JM, Hake PW, Denenberg A, Nowell M, Piraino G, Zingarelli B.

Mol Med. 2010 Nov-Dec;16(11-12):491-7. doi: 10.2119/molmed.2010.00063. Epub 2010 Aug 19.


Activation of AMPK-Sirt1 pathway by telmisartan in white adipose tissue: A possible link to anti-metabolic effects.

Shiota A, Shimabukuro M, Fukuda D, Soeki T, Sato H, Uematsu E, Hirata Y, Kurobe H, Sakaue H, Nakaya Y, Masuzaki H, Sata M.

Eur J Pharmacol. 2012 Oct 5;692(1-3):84-90. doi: 10.1016/j.ejphar.2012.07.026. Epub 2012 Jul 20.


Signaling pathway for adiponectin expression in adipocytes by osteocalcin.

Otani T, Mizokami A, Hayashi Y, Gao J, Mori Y, Nakamura S, Takeuchi H, Hirata M.

Cell Signal. 2015 Mar;27(3):532-44. doi: 10.1016/j.cellsig.2014.12.018. Epub 2015 Jan 3.


The frequency of daily ethanol consumption influences the effect of ethanol on insulin sensitivity in rats fed a high-fat diet.

Feng L, Han B, Wang R, Li Q, Bian D, Ma C, Song G, Gao L, Zhao J.

Br J Nutr. 2012 Mar;107(6):850-7. doi: 10.1017/S0007114511003722. Epub 2011 Sep 6.


Green tea polyphenols reduce body weight in rats by modulating obesity-related genes.

Lu C, Zhu W, Shen CL, Gao W.

PLoS One. 2012;7(6):e38332. doi: 10.1371/journal.pone.0038332. Epub 2012 Jun 8.


Serum adiponectin as a biomarker for in vivo PPARgamma activation and PPARgamma agonist-induced efficacy on insulin sensitization/lipid lowering in rats.

Yang B, Brown KK, Chen L, Carrick KM, Clifton LG, McNulty JA, Winegar DA, Strum JC, Stimpson SA, Pahel GL.

BMC Pharmacol. 2004 Oct 18;4:23.


Restoration of adiponectin expression via the ERK pathway in TNFα-treated 3T3-L1 adipocytes.

Chang E, Choi JM, Kim WJ, Rhee EJ, Oh KW, Lee WY, Park SE, Park SW, Park CY.

Mol Med Rep. 2014 Aug;10(2):905-10. doi: 10.3892/mmr.2014.2278. Epub 2014 May 28.


Flaxseed lignan attenuates high-fat diet-induced fat accumulation and induces adiponectin expression in mice.

Fukumitsu S, Aida K, Ueno N, Ozawa S, Takahashi Y, Kobori M.

Br J Nutr. 2008 Sep;100(3):669-76. doi: 10.1017/S0007114508911570. Epub 2008 Feb 6.


Inhibition of ERK1/2 pathway suppresses adiponectin secretion via accelerating protein degradation by Ubiquitin-proteasome system: relevance to obesity-related adiponectin decline.

Gu D, Wang Z, Dou X, Zhang X, Li S, Vu L, Yao T, Song Z.

Metabolism. 2013 Aug;62(8):1137-48. doi: 10.1016/j.metabol.2013.01.025. Epub 2013 Mar 12.


Inhibition of adiponectin production by homocysteine: a potential mechanism for alcoholic liver disease.

Song Z, Zhou Z, Deaciuc I, Chen T, McClain CJ.

Hepatology. 2008 Mar;47(3):867-79. doi: 10.1002/hep.22074.


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