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Items: 1 to 20 of 457

1.

MyD88 is essential to sustain mTOR activation necessary to promote T helper 17 cell proliferation by linking IL-1 and IL-23 signaling.

Chang J, Burkett PR, Borges CM, Kuchroo VK, Turka LA, Chang CH.

Proc Natl Acad Sci U S A. 2013 Feb 5;110(6):2270-5. doi: 10.1073/pnas.1206048110. Epub 2013 Jan 22.

2.

Bacillus-derived poly-γ-glutamic acid reciprocally regulates the differentiation of T helper 17 and regulatory T cells and attenuates experimental autoimmune encephalomyelitis.

Lee K, Hwang S, Paik DJ, Kim WK, Kim JM, Youn J.

Clin Exp Immunol. 2012 Oct;170(1):66-76. doi: 10.1111/j.1365-2249.2012.04637.x.

3.

Signaling through the adaptor molecule MyD88 in CD4+ T cells is required to overcome suppression by regulatory T cells.

Schenten D, Nish SA, Yu S, Yan X, Lee HK, Brodsky I, Pasman L, Yordy B, Wunderlich FT, Brüning JC, Zhao H, Medzhitov R.

Immunity. 2014 Jan 16;40(1):78-90. doi: 10.1016/j.immuni.2013.10.023. Erratum in: Immunity. 2014 May 15;40(5):814.

4.

Sox5 and c-Maf cooperatively induce Th17 cell differentiation via RORγt induction as downstream targets of Stat3.

Tanaka S, Suto A, Iwamoto T, Kashiwakuma D, Kagami S, Suzuki K, Takatori H, Tamachi T, Hirose K, Onodera A, Suzuki J, Ohara O, Yamashita M, Nakayama T, Nakajima H.

J Exp Med. 2014 Aug 25;211(9):1857-74. doi: 10.1084/jem.20130791. Epub 2014 Jul 29.

5.

Intrinsic MyD88-Akt1-mTOR Signaling Coordinates Disparate Tc17 and Tc1 Responses during Vaccine Immunity against Fungal Pneumonia.

Nanjappa SG, Hernández-Santos N, Galles K, Wüthrich M, Suresh M, Klein BS.

PLoS Pathog. 2015 Sep 14;11(9):e1005161. doi: 10.1371/journal.ppat.1005161. eCollection 2015 Sep.

6.

The receptor SIGIRR suppresses Th17 cell proliferation via inhibition of the interleukin-1 receptor pathway and mTOR kinase activation.

Gulen MF, Kang Z, Bulek K, Youzhong W, Kim TW, Chen Y, Altuntas CZ, Sass Bak-Jensen K, McGeachy MJ, Do JS, Xiao H, Delgoffe GM, Min B, Powell JD, Tuohy VK, Cua DJ, Li X.

Immunity. 2010 Jan 29;32(1):54-66. doi: 10.1016/j.immuni.2009.12.003. Epub 2010 Jan 7.

7.

Microglia Induce Neurotoxic IL-17+ γδ T Cells Dependent on TLR2, TLR4, and TLR9 Activation.

Derkow K, Krüger C, Dembny P, Lehnardt S.

PLoS One. 2015 Aug 19;10(8):e0135898. doi: 10.1371/journal.pone.0135898. eCollection 2015.

8.

T cell receptor/CARMA1/NF-κB signaling controls T-helper (Th) 17 differentiation.

Molinero LL, Cubre A, Mora-Solano C, Wang Y, Alegre ML.

Proc Natl Acad Sci U S A. 2012 Nov 6;109(45):18529-34. doi: 10.1073/pnas.1204557109. Epub 2012 Oct 22.

9.

Autoimmune memory T helper 17 cell function and expansion are dependent on interleukin-23.

Haines CJ, Chen Y, Blumenschein WM, Jain R, Chang C, Joyce-Shaikh B, Porth K, Boniface K, Mattson J, Basham B, Anderton SM, McClanahan TK, Sadekova S, Cua DJ, McGeachy MJ.

Cell Rep. 2013 May 30;3(5):1378-88. doi: 10.1016/j.celrep.2013.03.035. Epub 2013 Apr 25.

10.

Dehydrodiconiferyl alcohol (DHCA) modulates the differentiation of Th17 and Th1 cells and suppresses experimental autoimmune encephalomyelitis.

Lee J, Choi J, Lee W, Ko K, Kim S.

Mol Immunol. 2015 Dec;68(2 Pt B):434-44. doi: 10.1016/j.molimm.2015.09.028. Epub 2015 Oct 23.

PMID:
26477735
11.

T-bet is essential for Th1-mediated, but not Th17-mediated, CNS autoimmune disease.

O'Connor RA, Cambrook H, Huettner K, Anderton SM.

Eur J Immunol. 2013 Nov;43(11):2818-23. doi: 10.1002/eji.201343689. Epub 2013 Aug 21.

12.

Toll/Interleukin-1 Receptor Domain Derived from TcpC (TIR-TcpC) Ameliorates Experimental Autoimmune Arthritis by Down-modulating Th17 Cell Response.

Pasi S, Kant R, Surolia A.

J Biol Chem. 2016 Jun 3;291(23):12358-69. doi: 10.1074/jbc.M116.722801. Epub 2016 Mar 28.

13.

IL-15-dependent CD8+ CD122+ T cells ameliorate experimental autoimmune encephalomyelitis by modulating IL-17 production by CD4+ T cells.

Yu P, Bamford RN, Waldmann TA.

Eur J Immunol. 2014 Nov;44(11):3330-41. doi: 10.1002/eji.201444675.

14.

SLAM-SAP signaling promotes differentiation of IL-17-producing T cells and progression of experimental autoimmune encephalomyelitis.

Huang YH, Tsai K, Ma C, Vallance BA, Priatel JJ, Tan R.

J Immunol. 2014 Dec 15;193(12):5841-53. doi: 10.4049/jimmunol.1301435. Epub 2014 Oct 31.

15.

The myeloid differentiation factor 88 (MyD88) is required for CD4+ T cell effector function in a murine model of inflammatory bowel disease.

Fukata M, Breglio K, Chen A, Vamadevan AS, Goo T, Hsu D, Conduah D, Xu R, Abreu MT.

J Immunol. 2008 Feb 1;180(3):1886-94.

16.

Induction of interleukin-10 in the T helper type 17 effector population by the G protein coupled estrogen receptor (GPER) agonist G-1.

Brunsing RL, Prossnitz ER.

Immunology. 2011 Sep;134(1):93-106. doi: 10.1111/j.1365-2567.2011.03471.x. Epub 2011 Jul 2.

17.

Ghrelin inhibits the differentiation of T helper 17 cells through mTOR/STAT3 signaling pathway.

Xu Y, Li Z, Yin Y, Lan H, Wang J, Zhao J, Feng J, Li Y, Zhang W.

PLoS One. 2015 Feb 6;10(2):e0117081. doi: 10.1371/journal.pone.0117081. eCollection 2015.

18.

Early growth response gene-2 controls IL-17 expression and Th17 differentiation by negatively regulating Batf.

Miao T, Raymond M, Bhullar P, Ghaffari E, Symonds AL, Meier UC, Giovannoni G, Li S, Wang P.

J Immunol. 2013 Jan 1;190(1):58-65. doi: 10.4049/jimmunol.1200868. Epub 2012 Nov 30.

19.

Unexpected regulatory roles of TLR4 and TLR9 in experimental autoimmune encephalomyelitis.

Marta M, Andersson A, Isaksson M, Kämpe O, Lobell A.

Eur J Immunol. 2008 Feb;38(2):565-75. doi: 10.1002/eji.200737187.

20.

Nuclear receptor NR4A2 orchestrates Th17 cell-mediated autoimmune inflammation via IL-21 signalling.

Raveney BJ, Oki S, Yamamura T.

PLoS One. 2013;8(2):e56595. doi: 10.1371/journal.pone.0056595. Epub 2013 Feb 21.

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