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Items: 1 to 20 of 98

1.

Tyrosyl phosphorylated PAK1 regulates breast cancer cell motility in response to prolactin through filamin A.

Hammer A, Rider L, Oladimeji P, Cook L, Li Q, Mattingly RR, Diakonova M.

Mol Endocrinol. 2013 Mar;27(3):455-65. doi: 10.1210/me.2012-1291. Epub 2013 Jan 22.

2.

Adapter protein SH2B1beta binds filamin A to regulate prolactin-dependent cytoskeletal reorganization and cell motility.

Rider L, Diakonova M.

Mol Endocrinol. 2011 Jul;25(7):1231-43. doi: 10.1210/me.2011-0056. Epub 2011 May 12.

3.
4.

PAK1 regulates breast cancer cell invasion through secretion of matrix metalloproteinases in response to prolactin and three-dimensional collagen IV.

Rider L, Oladimeji P, Diakonova M.

Mol Endocrinol. 2013 Jul;27(7):1048-64. doi: 10.1210/me.2012-1322. Epub 2013 Jun 6.

5.

Phosphorylation of tyrosine 285 of PAK1 facilitates βPIX/GIT1 binding and adhesion turnover.

Hammer A, Oladimeji P, De Las Casas LE, Diakonova M.

FASEB J. 2015 Mar;29(3):943-59. doi: 10.1096/fj.14-259366. Epub 2014 Dec 2.

6.

Tyrosyl phosphorylated serine-threonine kinase PAK1 is a novel regulator of prolactin-dependent breast cancer cell motility and invasion.

Hammer A, Diakonova M.

Adv Exp Med Biol. 2015;846:97-137. doi: 10.1007/978-3-319-12114-7_5. Review.

7.

PAK1-Nck regulates cyclin D1 promoter activity in response to prolactin.

Tao J, Oladimeji P, Rider L, Diakonova M.

Mol Endocrinol. 2011 Sep;25(9):1565-78. doi: 10.1210/me.2011-0062. Epub 2011 Jun 30.

8.

JAK2 tyrosine kinase phosphorylates PAK1 and regulates PAK1 activity and functions.

Rider L, Shatrova A, Feener EP, Webb L, Diakonova M.

J Biol Chem. 2007 Oct 19;282(42):30985-96. Epub 2007 Aug 28.

9.

PAK1 translocates into nucleus in response to prolactin but not to estrogen.

Oladimeji P, Diakonova M.

Biochem Biophys Res Commun. 2016 Apr 22;473(1):206-211. doi: 10.1016/j.bbrc.2016.03.079. Epub 2016 Mar 19.

10.

Src tyrosyl phosphorylates cortactin in response to prolactin.

Hammer A, Laghate S, Diakonova M.

Biochem Biophys Res Commun. 2015 Aug 7;463(4):644-9. doi: 10.1016/j.bbrc.2015.05.116. Epub 2015 Jun 1.

11.

Synergistic Activation of ERα by Estrogen and Prolactin in Breast Cancer Cells Requires Tyrosyl Phosphorylation of PAK1.

Oladimeji P, Skerl R, Rusch C, Diakonova M.

Cancer Res. 2016 May 1;76(9):2600-11. doi: 10.1158/0008-5472.CAN-15-1758. Epub 2016 Mar 4.

12.

Filamin is essential in actin cytoskeletal assembly mediated by p21-activated kinase 1.

Vadlamudi RK, Li F, Adam L, Nguyen D, Ohta Y, Stossel TP, Kumar R.

Nat Cell Biol. 2002 Sep;4(9):681-90.

PMID:
12198493
13.

Regulatable expression of p21-activated kinase-1 promotes anchorage-independent growth and abnormal organization of mitotic spindles in human epithelial breast cancer cells.

Vadlamudi RK, Adam L, Wang RA, Mandal M, Nguyen D, Sahin A, Chernoff J, Hung MC, Kumar R.

J Biol Chem. 2000 Nov 17;275(46):36238-44.

14.

Global profiling of prolactin-modulated transcripts in breast cancer in vivo.

Sato T, Tran TH, Peck AR, Liu C, Ertel A, Lin J, Neilson LM, Rui H.

Mol Cancer. 2013 Jun 12;12:59. doi: 10.1186/1476-4598-12-59.

15.

Ribosomal S6 kinase (RSK) regulates phosphorylation of filamin A on an important regulatory site.

Woo MS, Ohta Y, Rabinovitz I, Stossel TP, Blenis J.

Mol Cell Biol. 2004 Apr;24(7):3025-35.

16.

Nek3 kinase regulates prolactin-mediated cytoskeletal reorganization and motility of breast cancer cells.

Miller SL, Antico G, Raghunath PN, Tomaszewski JE, Clevenger CV.

Oncogene. 2007 Jul 12;26(32):4668-78. Epub 2007 Feb 12.

PMID:
17297458
17.

Filamin A is a novel caveolin-1-dependent target in IGF-I-stimulated cancer cell migration.

Ravid D, Chuderland D, Landsman L, Lavie Y, Reich R, Liscovitch M.

Exp Cell Res. 2008 Sep 10;314(15):2762-73. doi: 10.1016/j.yexcr.2008.06.004. Epub 2008 Jun 12.

PMID:
18598695
18.

Etk/Bmx tyrosine kinase activates Pak1 and regulates tumorigenicity of breast cancer cells.

Bagheri-Yarmand R, Mandal M, Taludker AH, Wang RA, Vadlamudi RK, Kung HJ, Kumar R.

J Biol Chem. 2001 Aug 3;276(31):29403-9. Epub 2001 May 29.

19.

Filamin A links sphingosine kinase 1 and sphingosine-1-phosphate receptor 1 at lamellipodia to orchestrate cell migration.

Maceyka M, Alvarez SE, Milstien S, Spiegel S.

Mol Cell Biol. 2008 Sep;28(18):5687-97. doi: 10.1128/MCB.00465-08. Epub 2008 Jul 21.

20.

Regulation of tamoxifen sensitivity by a PAK1-EBP1 signalling pathway in breast cancer.

Ghosh A, Awasthi S, Peterson JR, Hamburger AW.

Br J Cancer. 2013 Feb 19;108(3):557-63. doi: 10.1038/bjc.2013.11. Epub 2013 Jan 29.

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