Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 122


Signaling dynamics of palmitate-induced ER stress responses mediated by ATF4 in HepG2 cells.

Cho H, Wu M, Zhang L, Thompson R, Nath A, Chan C.

BMC Syst Biol. 2013 Jan 22;7:9. doi: 10.1186/1752-0509-7-9.


Saturated fatty acid induction of endoplasmic reticulum stress and apoptosis in human liver cells via the PERK/ATF4/CHOP signaling pathway.

Cao J, Dai DL, Yao L, Yu HH, Ning B, Zhang Q, Chen J, Cheng WH, Shen W, Yang ZX.

Mol Cell Biochem. 2012 May;364(1-2):115-29. doi: 10.1007/s11010-011-1211-9. Epub 2012 Jan 15.


Nicotinamide ameliorates palmitate-induced ER stress in hepatocytes via cAMP/PKA/CREB pathway-dependent Sirt1 upregulation.

Li J, Dou X, Li S, Zhang X, Zeng Y, Song Z.

Biochim Biophys Acta. 2015 Nov;1853(11 Pt A):2929-36. doi: 10.1016/j.bbamcr.2015.09.003. Epub 2015 Sep 6.


Neuronal apoptosis induced by endoplasmic reticulum stress is regulated by ATF4-CHOP-mediated induction of the Bcl-2 homology 3-only member PUMA.

Galehdar Z, Swan P, Fuerth B, Callaghan SM, Park DS, Cregan SP.

J Neurosci. 2010 Dec 15;30(50):16938-48. doi: 10.1523/JNEUROSCI.1598-10.2010.


Anacardic acid induces cell apoptosis associated with induction of ATF4-dependent endoplasmic reticulum stress.

Huang H, Hua X, Liu N, Li X, Liu S, Chen X, Zhao C, Lan X, Yang C, Dou QP, Liu J.

Toxicol Lett. 2014 Aug 4;228(3):170-8. doi: 10.1016/j.toxlet.2014.05.012. Epub 2014 May 20.


ER stress activating ATF4/CHOP-TNF-α signaling pathway contributes to alcohol-induced disruption of osteogenic lineage of multipotential mesenchymal stem cell.

Chen Y, Gao H, Yin Q, Chen L, Dong P, Zhang X, Kang J.

Cell Physiol Biochem. 2013;32(3):743-54. doi: 10.1159/000354476. Epub 2013 Sep 13.


Palmitate causes endoplasmic reticulum stress and apoptosis in human mesenchymal stem cells: prevention by AMPK activator.

Lu J, Wang Q, Huang L, Dong H, Lin L, Lin N, Zheng F, Tan J.

Endocrinology. 2012 Nov;153(11):5275-84. doi: 10.1210/en.2012-1418. Epub 2012 Sep 11.


Impaired oxidative endoplasmic reticulum stress response caused by deficiency of thyroid hormone receptor α.

Takahashi K, Furuya F, Shimura H, Kaneshige M, Kobayashi T.

J Biol Chem. 2014 May 2;289(18):12485-93. doi: 10.1074/jbc.M113.544122. Epub 2014 Mar 18.


Upregulation of CHOP/GADD153 during coronavirus infectious bronchitis virus infection modulates apoptosis by restricting activation of the extracellular signal-regulated kinase pathway.

Liao Y, Fung TS, Huang M, Fang SG, Zhong Y, Liu DX.

J Virol. 2013 Jul;87(14):8124-34. doi: 10.1128/JVI.00626-13. Epub 2013 May 15.


Lipid-induced endoplasmic reticulum stress in liver cells results in two distinct outcomes: adaptation with enhanced insulin signaling or insulin resistance.

Achard CS, Laybutt DR.

Endocrinology. 2012 May;153(5):2164-77. doi: 10.1210/en.2011-1881. Epub 2012 Feb 28.


The double-strand RNA-dependent protein kinase PKR plays a significant role in a sustained ER stress-induced apoptosis.

Lee ES, Yoon CH, Kim YS, Bae YS.

FEBS Lett. 2007 Sep 4;581(22):4325-32. Epub 2007 Aug 14.


Reduced glutathione protects human hepatocytes from palmitate-mediated injury by suppressing endoplasmic reticulum stress response.

Ning B, Bai M, Shen W.

Hepatogastroenterology. 2011 Sep-Oct;58(110-111):1670-9. doi: 10.5754/hge10845. Epub 2011 Jul 15.


Apelin is transcriptionally regulated by ER stress-induced ATF4 expression via a p38 MAPK-dependent pathway.

Jeong K, Oh Y, Kim SJ, Kim H, Park KC, Kim SS, Ha J, Kang I, Choe W.

Apoptosis. 2014 Sep;19(9):1399-410. doi: 10.1007/s10495-014-1013-0.


PERK-eIF2α-ATF4-CHOP signaling contributes to TNFα-induced vascular calcification.

Masuda M, Miyazaki-Anzai S, Levi M, Ting TC, Miyazaki M.

J Am Heart Assoc. 2013 Sep 5;2(5):e000238. doi: 10.1161/JAHA.113.000238.


An ATF4-Signal-Modulating Machine Other Than GADD34 Acts in ATF4-to-CHOP Signaling to Block CHOP Expression in ER-Stress-Related Autophagy.

Iwasaki N, Sugiyama Y, Miyazaki S, Nakagawa H, Nishimura K, Matsuo S.

J Cell Biochem. 2015 Jul;116(7):1300-9. doi: 10.1002/jcb.25085.


Regulation of autophagy by ATF4 in response to severe hypoxia.

Rzymski T, Milani M, Pike L, Buffa F, Mellor HR, Winchester L, Pires I, Hammond E, Ragoussis I, Harris AL.

Oncogene. 2010 Aug 5;29(31):4424-35. doi: 10.1038/onc.2010.191. Epub 2010 May 31.


Valproate pretreatment protects pancreatic β-cells from palmitate-induced ER stress and apoptosis by inhibiting glycogen synthase kinase-3β.

Huang S, Zhu M, Wu W, Rashid A, Liang Y, Hou L, Ning Q, Luo X.

J Biomed Sci. 2014 May 4;21:38. doi: 10.1186/1423-0127-21-38.


Endoplasmic reticulum stress implicated in the development of renal fibrosis.

Chiang CK, Hsu SP, Wu CT, Huang JW, Cheng HT, Chang YW, Hung KY, Wu KD, Liu SH.

Mol Med. 2011;17(11-12):1295-305. doi: 10.2119/molmed.2011.00131. Epub 2011 Aug 19.

Supplemental Content

Support Center