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Items: 1 to 20 of 134

1.

Novel microemulsion of tanshinone IIA, isolated from Salvia miltiorrhiza Bunge, exerts anticancer activity through inducing apoptosis in hepatoma cells.

Ma H, Fan Q, Yu J, Xin J, Zhang C.

Am J Chin Med. 2013;41(1):197-210. doi: 10.1142/S0192415X13500146.

PMID:
23336516
2.

Anticancer activities of tanshinone microemulsion against hepatocellular carcinoma in vitro and in vivo.

Ma H, Fan Q, Yu J, Xin J, Zhang C.

Mol Med Rep. 2013 Jan;7(1):59-64. doi: 10.3892/mmr.2012.1129. Epub 2012 Oct 12.

PMID:
23064251
3.

Inhibition of cytochrome P450 2J2 by tanshinone IIA induces apoptotic cell death in hepatocellular carcinoma HepG2 cells.

Jeon YJ, Kim JS, Hwang GH, Wu Z, Han HJ, Park SH, Chang W, Kim LK, Lee YM, Liu KH, Lee MY.

Eur J Pharmacol. 2015 Oct 5;764:480-8. doi: 10.1016/j.ejphar.2015.07.047. Epub 2015 Jul 21.

PMID:
26209360
4.

Tanshinone IIA reduces apoptosis induced by hydrogen peroxide in the human endothelium-derived EA.hy926 cells.

Jia LQ, Yang GL, Ren L, Chen WN, Feng JY, Cao Y, Zhang L, Li XT, Lei P.

J Ethnopharmacol. 2012 Aug 30;143(1):100-8. doi: 10.1016/j.jep.2012.06.007. Epub 2012 Jun 28.

PMID:
22750433
5.

Tanshinone IIA activates calcium-dependent apoptosis signaling pathway in human hepatoma cells.

Dai ZK, Qin JK, Huang JE, Luo Y, Xu Q, Zhao HL.

J Nat Med. 2012 Jan;66(1):192-201. doi: 10.1007/s11418-011-0576-0. Epub 2011 Aug 19.

PMID:
21853384
6.

Tanshinone IIA inhibits the growth of pancreatic cancer BxPC‑3 cells by decreasing protein expression of TCTP, MCL‑1 and Bcl‑xL.

Huang CY, Chiu TL, Kuo SJ, Chien SY, Chen DR, Su CC.

Mol Med Rep. 2013 Mar;7(3):1045-9. doi: 10.3892/mmr.2013.1290. Epub 2013 Jan 25.

PMID:
23358553
7.

Tanshinone IIA inhibits human hepatocellular carcinoma J5 cell growth by increasing Bax and caspase 3 and decreasing CD31 expression in vivo.

Chien SY, Kuo SJ, Chen YL, Chen DR, Cheng CY, Su CC.

Mol Med Rep. 2012 Jan;5(1):282-6. doi: 10.3892/mmr.2011.631. Epub 2011 Oct 14.

PMID:
22002472
8.

Cooperative effect of Bifidobacteria lipoteichoic acid combined with 5-fluorouracil on hepatoma-22 cells growth and apoptosis.

Guo B, Xie N, Wang Y.

Bull Cancer. 2015 Mar;102(3):204-12. doi: 10.1016/j.bulcan.2014.09.003. Epub 2015 Mar 4.

PMID:
25747889
9.

Dioscin suppresses hepatocellular carcinoma tumor growth by inducing apoptosis and regulation of TP53, BAX, BCL2 and cleaved CASP3.

Zhang G, Zeng X, Zhang R, Liu J, Zhang W, Zhao Y, Zhang X, Wu Z, Tan Y, Wu Y, Du B.

Phytomedicine. 2016 Nov 15;23(12):1329-1336. doi: 10.1016/j.phymed.2016.07.003. Epub 2016 Jul 5.

PMID:
27765352
10.

Anticancer potential of aqueous extract of alocasia macrorrhiza against hepatic cancer in vitro and in vivo.

Fang S, Lin C, Zhang Q, Wang L, Lin P, Zhang J, Wang X.

J Ethnopharmacol. 2012 Jun 14;141(3):947-56. doi: 10.1016/j.jep.2012.03.037. Epub 2012 Mar 28.

PMID:
22472110
11.

A novel compound modified from tanshinone inhibits tumor growth in vivo via activation of the intrinsic apoptotic pathway.

Tian HL, Yu T, Xu NN, Feng C, Zhou LY, Luo HW, Chang DC, Le XF, Luo KQ.

Cancer Lett. 2010 Nov 1;297(1):18-30. doi: 10.1016/j.canlet.2010.04.020. Epub 2010 May 21.

PMID:
20494511
12.

Guggulsterone induces apoptosis of human hepatocellular carcinoma cells through intrinsic mitochondrial pathway.

Shi JJ, Jia XL, Li M, Yang N, Li YP, Zhang X, Gao N, Dang SS.

World J Gastroenterol. 2015 Dec 21;21(47):13277-87. doi: 10.3748/wjg.v21.i47.13277.

13.

Inhibitory effects of β,β-dimethylacrylshikonin on hepatocellular carcinoma in vitro and in vivo.

Wu YY, Wan LH, Zheng XW, Shao ZJ, Chen J, Chen XJ, Liu LT, Kuang WJ, Tan XS, Zhou LM.

Phytother Res. 2012 May;26(5):764-71. doi: 10.1002/ptr.3623. Epub 2011 Nov 23.

PMID:
22109831
14.

Sasanquasaponin from Camellia oleifera Abel. induces apoptosis via Bcl-2, Bax and caspase-3 activation in HepG2 cells.

Zeng J, Chen S, Li N, Chen L, Su J, Niu G, Zhu S, Liang Y.

Mol Med Rep. 2015 Aug;12(2):1997-2002. doi: 10.3892/mmr.2015.3666. Epub 2015 Apr 23.

PMID:
25937271
15.

Effect of tanshinone IIA in an in vitro model of Graves' orbitopathy.

Rhiu S, Chae MK, Lee EJ, Lee JB, Yoon JS.

Invest Ophthalmol Vis Sci. 2014 Aug 26;55(9):5900-10. doi: 10.1167/iovs.14-14008.

PMID:
25159204
16.

Tanshinone IIA induces mitochondria dependent apoptosis in prostate cancer cells in association with an inhibition of phosphoinositide 3-kinase/AKT pathway.

Won SH, Lee HJ, Jeong SJ, Lee HJ, Lee EO, Jung DB, Shin JM, Kwon TR, Yun SM, Lee MH, Choi SH, Lü J, Kim SH.

Biol Pharm Bull. 2010;33(11):1828-34.

17.

Cytotoxic effect and apoptotic mechanism of tanshinone A, a novel tanshinone derivative, on human erythroleukemic K562 cells.

Zhen X, Cen J, Li YM, Yan F, Guan T, Tang XZ.

Eur J Pharmacol. 2011 Sep 30;667(1-3):129-35. doi: 10.1016/j.ejphar.2011.06.004. Epub 2011 Jun 16.

PMID:
21699893
18.

Anti-Tumor Effects of the Polysaccharide Isolated from Tarphochlamys Affinis in H22 Tumor-Bearing Mice.

Tang X, Huang J, Xiong H, Zhang K, Chen C, Wei X, Xu X, Xie Q, Huang R.

Cell Physiol Biochem. 2016;39(3):1040-50. doi: 10.1159/000447811. Epub 2016 Aug 19.

19.

Total alkaloids of Rubus aleaefolius Poir inhibit hepatocellular carcinoma growth in vivo and in vitro via activation of mitochondrial-dependent apoptosis.

Zhao J, Chen X, Lin W, Wu G, Zhuang Q, Zhong X, Hong Z, Peng J.

Int J Oncol. 2013 Mar;42(3):971-8. doi: 10.3892/ijo.2013.1779. Epub 2013 Jan 18.

PMID:
23338043
20.

Crosstalk between Beclin-1-dependent autophagy and caspase‑dependent apoptosis induced by tanshinone IIA in human osteosarcoma MG-63 cells.

Ma K, Zhang C, Huang MY, Guo YX, Hu GQ.

Oncol Rep. 2016 Oct;36(4):1807-18. doi: 10.3892/or.2016.5003. Epub 2016 Aug 4.

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