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Items: 1 to 20 of 88

1.

IGF1 receptor signaling regulates adaptive radioprotection in glioma stem cells.

Osuka S, Sampetrean O, Shimizu T, Saga I, Onishi N, Sugihara E, Okubo J, Fujita S, Takano S, Matsumura A, Saya H.

Stem Cells. 2013 Apr;31(4):627-40. doi: 10.1002/stem.1328.

2.

Post-transcriptional regulation of IGF1R by key microRNAs in long-lived mutant mice.

Liang R, Khanna A, Muthusamy S, Li N, Sarojini H, Kopchick JJ, Masternak MM, Bartke A, Wang E.

Aging Cell. 2011 Dec;10(6):1080-8. doi: 10.1111/j.1474-9726.2011.00751.x.

3.

Activation of the phosphorylation of ATM contributes to radioresistance of glioma stem cells.

Zhou W, Sun M, Li GH, Wu YZ, Wang Y, Jin F, Zhang YY, Yang L, Wang DL.

Oncol Rep. 2013 Oct;30(4):1793-801. doi: 10.3892/or.2013.2614. Epub 2013 Jul 11.

PMID:
23846672
5.
6.

Notch signaling contributes to the maintenance of both normal neural stem cells and patient-derived glioma stem cells.

Hu YY, Zheng MH, Cheng G, Li L, Liang L, Gao F, Wei YN, Fu LA, Han H.

BMC Cancer. 2011 Feb 22;11:82. doi: 10.1186/1471-2407-11-82.

7.

A new 2-pyrone derivative, 5-bromo-3-(3-hydroxyprop-1-ynyl)-2H-pyran-2-one, suppresses stemness in glioma stem-like cells.

Kim RK, Kim MJ, Yoon CH, Lim EJ, Yoo KC, Lee GH, Kim YH, Kim H, Jin YB, Lee YJ, Cho CG, Oh YS, Gye MC, Suh Y, Lee SJ.

Mol Pharmacol. 2012 Sep;82(3):400-7. doi: 10.1124/mol.112.078402. Epub 2012 May 30.

8.

Glioma Stem Cells but Not Bulk Glioma Cells Upregulate IL-6 Secretion in Microglia/Brain Macrophages via Toll-like Receptor 4 Signaling.

a Dzaye OD, Hu F, Derkow K, Haage V, Euskirchen P, Harms C, Lehnardt S, Synowitz M, Wolf SA, Kettenmann H.

J Neuropathol Exp Neurol. 2016 May;75(5):429-40. doi: 10.1093/jnen/nlw016. Epub 2016 Mar 30.

9.

An integrin binding-defective mutant of insulin-like growth factor-1 (R36E/R37E IGF1) acts as a dominant-negative antagonist of the IGF1 receptor (IGF1R) and suppresses tumorigenesis but still binds to IGF1R.

Fujita M, Ieguchi K, Cedano-Prieto DM, Fong A, Wilkerson C, Chen JQ, Wu M, Lo SH, Cheung AT, Wilson MD, Cardiff RD, Borowsky AD, Takada YK, Takada Y.

J Biol Chem. 2013 Jul 5;288(27):19593-603. doi: 10.1074/jbc.M113.470872. Epub 2013 May 21.

10.

Effect of hypoxia on the expression of genes encoding insulin-like growth factors and some related proteins in U87 glioma cells without IRE1 function.

Minchenko DO, Kharkova AP, Halkin OV, Karbovskyi LL, Minchenko OH.

Endocr Regul. 2016 Apr;50(2):43-54. doi: 10.1515/enr-2016-0008.

PMID:
27560636
11.

Cross-talk between integrin α6β4 and insulin-like growth factor-1 receptor (IGF1R) through direct α6β4 binding to IGF1 and subsequent α6β4-IGF1-IGF1R ternary complex formation in anchorage-independent conditions.

Fujita M, Ieguchi K, Davari P, Yamaji S, Taniguchi Y, Sekiguchi K, Takada YK, Takada Y.

J Biol Chem. 2012 Apr 6;287(15):12491-500. doi: 10.1074/jbc.M111.304170. Epub 2012 Feb 20.

12.

Tumor-specific activation of the C-JUN/MELK pathway regulates glioma stem cell growth in a p53-dependent manner.

Gu C, Banasavadi-Siddegowda YK, Joshi K, Nakamura Y, Kurt H, Gupta S, Nakano I.

Stem Cells. 2013 May;31(5):870-81. doi: 10.1002/stem.1322.

13.

IGF1R blockade with ganitumab results in systemic effects on the GH-IGF axis in mice.

Moody G, Beltran PJ, Mitchell P, Cajulis E, Chung YA, Hwang D, Kendall R, Radinsky R, Cohen P, Calzone FJ.

J Endocrinol. 2014 Mar 17;221(1):145-55. doi: 10.1530/JOE-13-0306. Print 2014 Apr.

14.

Pterostilbene suppressed irradiation-resistant glioma stem cells by modulating GRP78/miR-205 axis.

Huynh TT, Lin CM, Lee WH, Wu AT, Lin YK, Lin YF, Yeh CT, Wang LS.

J Nutr Biochem. 2015 May;26(5):466-75. doi: 10.1016/j.jnutbio.2014.11.015. Epub 2015 Jan 19.

PMID:
25736407
15.

Hedgehog/GLI1 regulates IGF dependent malignant behaviors in glioma stem cells.

Hsieh A, Ellsworth R, Hsieh D.

J Cell Physiol. 2011 Apr;226(4):1118-27. doi: 10.1002/jcp.22433.

PMID:
20857406
16.

Impaired IGF1R signaling in cells expressing longevity-associated human IGF1R alleles.

Tazearslan C, Huang J, Barzilai N, Suh Y.

Aging Cell. 2011 Jun;10(3):551-4. doi: 10.1111/j.1474-9726.2011.00697.x. Epub 2011 Apr 12.

17.

Knockdown of miR-210 decreases hypoxic glioma stem cells stemness and radioresistance.

Yang W, Wei J, Guo T, Shen Y, Liu F.

Exp Cell Res. 2014 Aug 1;326(1):22-35. doi: 10.1016/j.yexcr.2014.05.022. Epub 2014 Jun 12.

PMID:
24930954
18.

Nanog regulates self-renewal of cancer stem cells through the insulin-like growth factor pathway in human hepatocellular carcinoma.

Shan J, Shen J, Liu L, Xia F, Xu C, Duan G, Xu Y, Ma Q, Yang Z, Zhang Q, Ma L, Liu J, Xu S, Yan X, Bie P, Cui Y, Bian XW, Qian C.

Hepatology. 2012 Sep;56(3):1004-14. doi: 10.1002/hep.25745. Epub 2012 Jul 12.

PMID:
22473773
19.

Akt regulates the survival of vascular smooth muscle cells via inhibition of FoxO3a and GSK3.

Allard D, Figg N, Bennett MR, Littlewood TD.

J Biol Chem. 2008 Jul 11;283(28):19739-47. doi: 10.1074/jbc.M710098200. Epub 2008 May 5.

20.

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