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Items: 1 to 20 of 275

1.

Benzimidazole clubbed with triazolo-thiadiazoles and triazolo-thiadiazines: new anticancer agents.

Husain A, Rashid M, Shaharyar M, Siddiqui AA, Mishra R.

Eur J Med Chem. 2013 Apr;62:785-98. doi: 10.1016/j.ejmech.2012.07.011. Epub 2012 Jul 16.

PMID:
23333063
2.

Benzimidazole bearing oxadiazole and triazolo-thiadiazoles nucleus: design and synthesis as anticancer agents.

Husain A, Rashid M, Mishra R, Parveen S, Shin DS, Kumar D.

Bioorg Med Chem Lett. 2012 Sep 1;22(17):5438-44. doi: 10.1016/j.bmcl.2012.07.038. Epub 2012 Jul 17.

PMID:
22840417
3.

Synthesis, crystal structure and biological evaluation of some novel 1,2,4-triazolo[3,4-b]-1,3,4-thiadiazoles and 1,2,4-triazolo[3,4-b]-1,3,4-thiadiazines.

Khan I, Zaib S, Ibrar A, Rama NH, Simpson J, Iqbal J.

Eur J Med Chem. 2014 May 6;78:167-77. doi: 10.1016/j.ejmech.2014.03.046. Epub 2014 Mar 19.

PMID:
24681981
4.

Synthesis and anticancer activities of new Benzothiadiazinyl Hydrazinecarboxamides and Anilino[1,2,4]triazolo[1,5-b][1,2,4]thiadiazine 5,5-diones.

Kamal A, Srikanth YV, Ashraf M, Khan MN, Shaik TB, Kalivendi SV, Suri N, Saxena AK.

Med Chem. 2011 May;7(3):165-72. doi: 1573-4064/11 $58.00+.00.

PMID:
21486211
5.

Synthesis of benzimidazoles bearing oxadiazole nucleus as anticancer agents.

Rashid M, Husain A, Mishra R.

Eur J Med Chem. 2012 Aug;54:855-66. doi: 10.1016/j.ejmech.2012.04.027. Epub 2012 May 9.

PMID:
22608854
6.

Synthesis of novel 1,2,4-triazoles, triazolothiadiazines and triazolothiadiazoles as potential anticancer agents.

Kamel MM, Megally Abdo NY.

Eur J Med Chem. 2014 Oct 30;86:75-80. doi: 10.1016/j.ejmech.2014.08.047. Epub 2014 Aug 15.

PMID:
25147148
7.

2,6-Disubstituted imidazo[2,1-b][1,3,4]thiadiazoles: search for anticancer agents.

Noolvi MN, Patel HM, Kamboj S, Kaur A, Mann V.

Eur J Med Chem. 2012 Oct;56:56-69. doi: 10.1016/j.ejmech.2012.08.012. Epub 2012 Aug 16.

PMID:
22960694
8.

Synthesis, anticancer activity and effects on cell cycle profile and apoptosis of novel thieno[2,3-d]pyrimidine and thieno[3,2-e] triazolo[4,3-c]pyrimidine derivatives.

Kandeel MM, Refaat HM, Kassab AE, Shahin IG, Abdelghany TM.

Eur J Med Chem. 2015 Jan 27;90:620-32. doi: 10.1016/j.ejmech.2014.12.009. Epub 2014 Dec 6.

PMID:
25499930
9.

In-vitro anti-HIV and antitumor activity of new 3,6-disubstituted [1,2,4]triazolo[3,4-b][1,3,4]thiadiazoles and thiadiazine analogues.

Al-Soud YA, Al-Masoudi NA, Loddo R, La Colla P.

Arch Pharm (Weinheim). 2008 Jun;341(6):365-9. doi: 10.1002/ardp.200700272.

PMID:
18493972
10.

New sulphonamide and carboxamide derivatives of acyclic C-nucleosides of triazolo-thiadiazole and the thiadiazine analogues. Synthesis, anti-HIV, and antitumor activities. Part 2.

Al-Masoudi NA, Al-Soud YA.

Nucleosides Nucleotides Nucleic Acids. 2008 Sep;27(9):1034-44. doi: 10.1080/15257770802271771.

PMID:
18711666
11.

An unexpected Dimroth rearrangement leading to annelated thieno[3,2-d][1,2,3]triazolo[1,5-a]pyrimidines with potent antitumor activity.

Lauria A, Patella C, Abbate I, Martorana A, Almerico AM.

Eur J Med Chem. 2013 Jul;65:381-8. doi: 10.1016/j.ejmech.2013.05.012. Epub 2013 May 20.

PMID:
23747807
12.

Synthesis, characterization and in vitro anticancer evaluation of novel 1,2,4-triazolin-3-one derivatives.

Kattimani PP, Kamble RR, Kariduraganavar MY, Dorababu A, Hunnur RK.

Eur J Med Chem. 2013 Apr;62:232-40. doi: 10.1016/j.ejmech.2013.01.004. Epub 2013 Jan 11.

PMID:
23353755
13.
14.

Design, synthesis and biological evaluation of novel 1,2,4-triazolo [3,4-b][1,3,4] thiadiazines bearing furan and thiophene nucleus.

Zhang B, Li YH, Liu Y, Chen YR, Pan ES, You WW, Zhao PL.

Eur J Med Chem. 2015 Oct 20;103:335-42. doi: 10.1016/j.ejmech.2015.08.053. Epub 2015 Sep 5.

PMID:
26363869
15.

Synthesis and cytotoxicity of 3,4-disubstituted-5-(3,4,5-trimethoxyphenyl)-4H-1,2,4-triazoles and novel 5,6-dihydro-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole derivatives bearing 3,4,5-trimethoxyphenyl moiety.

Zhao PL, Duan AN, Zou M, Yang HK, You WW, Wu SG.

Bioorg Med Chem Lett. 2012 Jul 1;22(13):4471-4. doi: 10.1016/j.bmcl.2012.03.023. Epub 2012 Mar 11. Erratum in: Bioorg Med Chem Lett. 2015 Sep 1;25(17):3754.

PMID:
22647723
16.

Synthesis, biological evaluation, and molecular docking studies of 1,3,4-thiadiazol-2-amide derivatives as novel anticancer agents.

Yang XH, Xiang L, Li X, Zhao TT, Zhang H, Zhou WP, Wang XM, Gong HB, Zhu HL.

Bioorg Med Chem. 2012 May 1;20(9):2789-95. doi: 10.1016/j.bmc.2012.03.040. Epub 2012 Mar 24.

PMID:
22503364
17.

New annelated thieno[2,3-e][1,2,3]triazolo[1,5-a]pyrimidines, with potent anticancer activity, designed through VLAK protocol.

Lauria A, Abbate I, Patella C, Martorana A, Dattolo G, Almerico AM.

Eur J Med Chem. 2013 Apr;62:416-24. doi: 10.1016/j.ejmech.2013.01.019. Epub 2013 Jan 23.

PMID:
23395722
18.

Synthesis of new conjugated coumarin-benzimidazole hybrids and their anticancer activity.

Paul K, Bindal S, Luxami V.

Bioorg Med Chem Lett. 2013 Jun 15;23(12):3667-72. doi: 10.1016/j.bmcl.2012.12.071. Epub 2013 Jan 4.

PMID:
23642480
19.

Synthesis and in vitro antitumor evaluation of primary amine substituted quinazoline linked benzimidazole.

Paul K, Sharma A, Luxami V.

Bioorg Med Chem Lett. 2014 Jan 15;24(2):624-9. doi: 10.1016/j.bmcl.2013.12.005. Epub 2013 Dec 8.

PMID:
24360999
20.

Optimization of pyrazole-containing 1,2,4-triazolo-[3,4-b]thiadiazines, a new class of STAT3 pathway inhibitors.

LaPorte MG, Wang Z, Colombo R, Garzan A, Peshkov VA, Liang M, Johnston PA, Schurdak ME, Sen M, Camarco DP, Hua Y, Pollock NI, Lazo JS, Grandis JR, Wipf P, Huryn DM.

Bioorg Med Chem Lett. 2016 Aug 1;26(15):3581-5. doi: 10.1016/j.bmcl.2016.06.017. Epub 2016 Jun 9.

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