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Items: 1 to 20 of 108

1.

A host GPCR signaling network required for the cytolysis of infected cells facilitates release of apicomplexan parasites.

Millholland MG, Mishra S, Dupont CD, Love MS, Patel B, Shilling D, Kazanietz MG, Foskett JK, Hunter CA, Sinnis P, Greenbaum DC.

Cell Host Microbe. 2013 Jan 16;13(1):15-28. doi: 10.1016/j.chom.2012.12.001. Epub 2013 Jan 16.

2.

Host cell egress and invasion induce marked relocations of glycolytic enzymes in Toxoplasma gondii tachyzoites.

Pomel S, Luk FC, Beckers CJ.

PLoS Pathog. 2008 Oct;4(10):e1000188. doi: 10.1371/journal.ppat.1000188. Epub 2008 Oct 24.

3.

A Genome-wide CRISPR Screen in Toxoplasma Identifies Essential Apicomplexan Genes.

Sidik SM, Huet D, Ganesan SM, Huynh MH, Wang T, Nasamu AS, Thiru P, Saeij JPJ, Carruthers VB, Niles JC, Lourido S.

Cell. 2016 Sep 8;166(6):1423-1435.e12. doi: 10.1016/j.cell.2016.08.019. Epub 2016 Sep 2.

4.

Apicomplexan parasites co-opt host calpains to facilitate their escape from infected cells.

Chandramohanadas R, Davis PH, Beiting DP, Harbut MB, Darling C, Velmourougane G, Lee MY, Greer PA, Roos DS, Greenbaum DC.

Science. 2009 May 8;324(5928):794-7. doi: 10.1126/science.1171085. Epub 2009 Apr 2.

5.

The malaria parasite progressively dismantles the host erythrocyte cytoskeleton for efficient egress.

Millholland MG, Chandramohanadas R, Pizzarro A, Wehr A, Shi H, Darling C, Lim CT, Greenbaum DC.

Mol Cell Proteomics. 2011 Dec;10(12):M111.010678. doi: 10.1074/mcp.M111.010678. Epub 2011 Sep 8.

6.

Serum response factor regulates immediate early host gene expression in Toxoplasma gondii-infected host cells.

Wiley M, Teygong C, Phelps E, Radke J, Blader IJ.

PLoS One. 2011 Mar 29;6(3):e18335. doi: 10.1371/journal.pone.0018335.

7.

Externally triggered egress is the major fate of Toxoplasma gondii during acute infection.

Tomita T, Yamada T, Weiss LM, Orlofsky A.

J Immunol. 2009 Nov 15;183(10):6667-80. doi: 10.4049/jimmunol.0900516. Epub 2009 Oct 21.

8.

Multimeric assembly of host-pathogen adhesion complexes involved in apicomplexan invasion.

Paing MM, Tolia NH.

PLoS Pathog. 2014 Jun 12;10(6):e1004120. doi: 10.1371/journal.ppat.1004120. eCollection 2014 Jun. No abstract available.

9.

Identification of potent phosphodiesterase inhibitors that demonstrate cyclic nucleotide-dependent functions in apicomplexan parasites.

Howard BL, Harvey KL, Stewart RJ, Azevedo MF, Crabb BS, Jennings IG, Sanders PR, Manallack DT, Thompson PE, Tonkin CJ, Gilson PR.

ACS Chem Biol. 2015 Apr 17;10(4):1145-54. doi: 10.1021/cb501004q. Epub 2015 Feb 4.

PMID:
25555060
10.

How Toxoplasma and malaria parasites defy first, then exploit host autophagic and endocytic pathways for growth.

Coppens I.

Curr Opin Microbiol. 2017 Dec;40:32-39. doi: 10.1016/j.mib.2017.10.009. Epub 2017 Nov 3. Review.

PMID:
29102900
11.

The conserved apicomplexan Aurora kinase TgArk3 is involved in endodyogeny, duplication rate and parasite virulence.

Berry L, Chen CT, Reininger L, Carvalho TG, El Hajj H, Morlon-Guyot J, Bordat Y, Lebrun M, Gubbels MJ, Doerig C, Daher W.

Cell Microbiol. 2016 Aug;18(8):1106-1120. doi: 10.1111/cmi.12571. Epub 2016 Feb 22.

12.

Human erythrocyte remodelling during Plasmodium falciparum malaria parasite growth and egress.

Mbengue A, Yam XY, Braun-Breton C.

Br J Haematol. 2012 Apr;157(2):171-9. doi: 10.1111/j.1365-2141.2012.09044.x. Epub 2012 Feb 7. Review.

PMID:
22313394
13.

TgCDPK3 regulates calcium-dependent egress of Toxoplasma gondii from host cells.

McCoy JM, Whitehead L, van Dooren GG, Tonkin CJ.

PLoS Pathog. 2012;8(12):e1003066. doi: 10.1371/journal.ppat.1003066. Epub 2012 Dec 4.

14.

Membrane trafficking and remodeling at the host-parasite interface.

Santi-Rocca J, Blanchard N.

Curr Opin Microbiol. 2017 Dec;40:145-151. doi: 10.1016/j.mib.2017.11.013. Epub 2017 Nov 22. Review.

PMID:
29175340
15.

Toxoplasma gondii infection confers resistance against BimS-induced apoptosis by preventing the activation and mitochondrial targeting of pro-apoptotic Bax.

Hippe D, Weber A, Zhou L, Chang DC, Häcker G, Lüder CG.

J Cell Sci. 2009 Oct 1;122(Pt 19):3511-21. doi: 10.1242/jcs.050963. Epub 2009 Sep 8.

16.

Analysis of Ca2+ mediated signaling regulating Toxoplasma infectivity reveals complex relationships between key molecules.

Stewart RJ, Whitehead L, Nijagal B, Sleebs BE, Lessene G, McConville MJ, Rogers KL, Tonkin CJ.

Cell Microbiol. 2017 Apr;19(4). doi: 10.1111/cmi.12685. Epub 2017 Jan 9.

PMID:
27781359
17.

[The glideosome, a unique machinery that assists the Apicomplexa in gliding into host cells].

Frénal K, Soldati-Favre D.

Med Sci (Paris). 2013 May;29(5):515-22. doi: 10.1051/medsci/2013295015. Epub 2013 May 28. French.

18.

Influence of low-density lipoprotein (LDL) receptor on lipid composition, inflammation and parasitism during Toxoplasma gondii infection.

Portugal LR, Fernandes LR, Pietra Pedroso VS, Santiago HC, Gazzinelli RT, Alvarez-Leite JI.

Microbes Infect. 2008 Mar;10(3):276-84. doi: 10.1016/j.micinf.2007.12.001. Epub 2007 Dec 8.

PMID:
18316222
20.

Targeted Phenotypic Screening in Plasmodium falciparum and Toxoplasma gondii Reveals Novel Modes of Action of Medicines for Malaria Venture Malaria Box Molecules.

Subramanian G, Belekar MA, Shukla A, Tong JX, Sinha A, Chu TTT, Kulkarni AS, Preiser PR, Reddy DS, Tan KSW, Shanmugam D, Chandramohanadas R.

mSphere. 2018 Jan 17;3(1). pii: e00534-17. doi: 10.1128/mSphere.00534-17. eCollection 2018 Jan-Feb.

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