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Immunohistochemical staining of B7-H1 (PD-L1) on paraffin-embedded slides of pancreatic adenocarcinoma tissue.

Bigelow E, Bever KM, Xu H, Yager A, Wu A, Taube J, Chen L, Jaffee EM, Anders RA, Zheng L.

J Vis Exp. 2013 Jan 3;(71). pii: 4059. doi: 10.3791/4059.


Blockade of B7-H1 or B7-DC induces an anti-tumor effect in a mouse pancreatic cancer model.

Okudaira K, Hokari R, Tsuzuki Y, Okada Y, Komoto S, Watanabe C, Kurihara C, Kawaguchi A, Nagao S, Azuma M, Yagita H, Miura S.

Int J Oncol. 2009 Oct;35(4):741-9.


Clinical significance and therapeutic potential of the programmed death-1 ligand/programmed death-1 pathway in human pancreatic cancer.

Nomi T, Sho M, Akahori T, Hamada K, Kubo A, Kanehiro H, Nakamura S, Enomoto K, Yagita H, Azuma M, Nakajima Y.

Clin Cancer Res. 2007 Apr 1;13(7):2151-7.


B7-H1 expression is associated with expansion of regulatory T cells in colorectal carcinoma.

Hua D, Sun J, Mao Y, Chen LJ, Wu YY, Zhang XG.

World J Gastroenterol. 2012 Mar 7;18(9):971-8. doi: 10.3748/wjg.v18.i9.971.


FOXP3+ Tregs and B7-H1+/PD-1+ T lymphocytes co-infiltrate the tumor tissues of high-risk breast cancer patients: Implication for immunotherapy.

Ghebeh H, Barhoush E, Tulbah A, Elkum N, Al-Tweigeri T, Dermime S.

BMC Cancer. 2008 Feb 23;8:57. doi: 10.1186/1471-2407-8-57.


Overexpression of B7-H1 correlates with malignant cell proliferation in pancreatic cancer.

Song X, Liu J, Lu Y, Jin H, Huang D.

Oncol Rep. 2014 Mar;31(3):1191-8. doi: 10.3892/or.2013.2955. Epub 2013 Dec 31.


Antagonist antibodies to PD-1 and B7-H1 (PD-L1) in the treatment of advanced human cancer.

Sznol M, Chen L.

Clin Cancer Res. 2013 Mar 1;19(5):1021-34. doi: 10.1158/1078-0432.CCR-12-2063.


B7-H1 protein vaccine induces protective and therapeutic antitumor responses in SP2/0 myeloma-bearing mice.

Zhang C, Wang W, Qin X, Xu Y, Huang T, Hao Q, Li W, Wu S, Zhang Y.

Oncol Rep. 2013 Nov;30(5):2442-8. doi: 10.3892/or.2013.2686. Epub 2013 Aug 22.


B7-H1 expression associates with tumor invasion and predicts patient's survival in human esophageal cancer.

Chen L, Deng H, Lu M, Xu B, Wang Q, Jiang J, Wu C.

Int J Clin Exp Pathol. 2014 Aug 15;7(9):6015-23. eCollection 2014.


Blockade of PD-L1 (B7-H1) augments human tumor-specific T cell responses in vitro.

Blank C, Kuball J, Voelkl S, Wiendl H, Becker B, Walter B, Majdic O, Gajewski TF, Theobald M, Andreesen R, Mackensen A.

Int J Cancer. 2006 Jul 15;119(2):317-27.


Colocalization of inflammatory response with B7-h1 expression in human melanocytic lesions supports an adaptive resistance mechanism of immune escape.

Taube JM, Anders RA, Young GD, Xu H, Sharma R, McMiller TL, Chen S, Klein AP, Pardoll DM, Topalian SL, Chen L.

Sci Transl Med. 2012 Mar 28;4(127):127ra37. doi: 10.1126/scitranslmed.3003689.


Significance of B7-H1 overexpression in kidney cancer.

Thompson RH, Kwon ED.

Clin Genitourin Cancer. 2006 Dec;5(3):206-11. Review.


Doxorubicin downregulates cell surface B7-H1 expression and upregulates its nuclear expression in breast cancer cells: role of B7-H1 as an anti-apoptotic molecule.

Ghebeh H, Lehe C, Barhoush E, Al-Romaih K, Tulbah A, Al-Alwan M, Hendrayani SF, Manogaran P, Alaiya A, Al-Tweigeri T, Aboussekhra A, Dermime S.

Breast Cancer Res. 2010;12(4):R48. doi: 10.1186/bcr2605. Epub 2010 Jul 13.


Implications of B7-H1 expression in clear cell carcinoma of the kidney for prognostication and therapy.

Thompson RH, Dong H, Kwon ED.

Clin Cancer Res. 2007 Jan 15;13(2 Pt 2):709s-715s. Review.


5-Fluorouracil upregulates cell surface B7-H1 (PD-L1) expression in gastrointestinal cancers.

Van Der Kraak L, Goel G, Ramanan K, Kaltenmeier C, Zhang L, Normolle DP, Freeman GJ, Tang D, Nason KS, Davison JM, Luketich JD, Dhupar R, Lotze MT.

J Immunother Cancer. 2016 Oct 18;4:65. eCollection 2016.


Identification and Characterization of MEDI4736, an Antagonistic Anti-PD-L1 Monoclonal Antibody.

Stewart R, Morrow M, Hammond SA, Mulgrew K, Marcus D, Poon E, Watkins A, Mullins S, Chodorge M, Andrews J, Bannister D, Dick E, Crawford N, Parmentier J, Alimzhanov M, Babcook JS, Foltz IN, Buchanan A, Bedian V, Wilkinson RW, McCourt M.

Cancer Immunol Res. 2015 Sep;3(9):1052-62. doi: 10.1158/2326-6066.CIR-14-0191. Epub 2015 May 5.


B7-H1 expression model for immune evasion in human papillomavirus-related oropharyngeal squamous cell carcinoma.

Ukpo OC, Thorstad WL, Lewis JS Jr.

Head Neck Pathol. 2013 Jun;7(2):113-21. doi: 10.1007/s12105-012-0406-z. Epub 2012 Nov 20.


Oral Squamous Carcinoma Cells Express B7-H1 and B7-DC Receptors in Vivo.

Groeger S, Howaldt HP, Raifer H, Gattenloehner S, Chakraborty T, Meyle J.

Pathol Oncol Res. 2017 Jan;23(1):99-110. doi: 10.1007/s12253-016-0100-7. Epub 2016 Aug 8.


T-cell coregulatory molecule expression in urothelial cell carcinoma: clinicopathologic correlations and association with survival.

Boorjian SA, Sheinin Y, Crispen PL, Farmer SA, Lohse CM, Kuntz SM, Leibovich BC, Kwon ED, Frank I.

Clin Cancer Res. 2008 Aug 1;14(15):4800-8. doi: 10.1158/1078-0432.CCR-08-0731.


Association of T-cell co-regulatory protein expression with clinical outcomes following radical cystectomy for urothelial carcinoma of the bladder.

Xylinas E, Robinson BD, Kluth LA, Volkmer BG, Hautmann R, K├╝fer R, Zerbib M, Kwon E, Thompson RH, Boorjian SA, Shariat SF.

Eur J Surg Oncol. 2014 Jan;40(1):121-7. doi: 10.1016/j.ejso.2013.08.023. Epub 2013 Sep 18.


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