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Items: 1 to 20 of 95

1.

Alkaloids from Microcos paniculata with cytotoxic and nicotinic receptor antagonistic activities.

Still PC, Yi B, González-Cestari TF, Pan L, Pavlovicz RE, Chai HB, Ninh TN, Li C, Soejarto DD, McKay DB, Kinghorn AD.

J Nat Prod. 2013 Feb 22;76(2):243-9. doi: 10.1021/np3007414. Epub 2013 Jan 17.

2.

A new piperidine alkaloid from the leaves of Microcos paniculata L.

Zhang G, Zhang N, Xu L, Wu HT, Chen D, Lin QH, Luo LZ.

Nat Prod Res. 2017 Jan;31(2):169-174. Epub 2016 Aug 24.

PMID:
27553201
3.

Two new piperidine alkaloids from the leaves of Microcos paniculata.

Feng SX, Lin LD, Xu HH, Wei XY.

J Asian Nat Prod Res. 2008 Nov-Dec;10(11-12):1155-8. doi: 10.1080/10286020802361289.

PMID:
19031262
4.

Negative allosteric modulators that target human alpha4beta2 neuronal nicotinic receptors.

Henderson BJ, Pavlovicz RE, Allen JD, González-Cestari TF, Orac CM, Bonnell AB, Zhu MX, Boyd RT, Li C, Bergmeier SC, McKay DB.

J Pharmacol Exp Ther. 2010 Sep 1;334(3):761-74. doi: 10.1124/jpet.110.168211. Epub 2010 Jun 15.

5.

Pharmacological and molecular studies on the interaction of varenicline with different nicotinic acetylcholine receptor subtypes. Potential mechanism underlying partial agonism at human α4β2 and α3β4 subtypes.

Arias HR, Feuerbach D, Targowska-Duda K, Kaczor AA, Poso A, Jozwiak K.

Biochim Biophys Acta. 2015 Feb;1848(2):731-41. doi: 10.1016/j.bbamem.2014.11.003. Epub 2014 Dec 2.

6.

(-)-Pentylsedinine, a New Alkaloid from the Leaves of Lobelia tupa with Agonist Activity at Nicotinic Acetylcholine Receptor.

Paz C, Becerra J, Silva M, Burgosa V, Heydenreich M, Schmidt B, Tran T, Vetter I.

Nat Prod Commun. 2015 Aug;10(8):1355-7.

PMID:
26434115
7.

Methadone is a non-competitive antagonist at the α4β2 and α3* nicotinic acetylcholine receptors and an agonist at the α7 nicotinic acetylcholine receptor.

Talka R, Salminen O, Tuominen RK.

Basic Clin Pharmacol Toxicol. 2015 Apr;116(4):321-8. doi: 10.1111/bcpt.12317. Epub 2014 Oct 7.

8.

[Seperation and structure elucidation of alkaloids from Chinese drug buzhaye, Folium Microcos].

Luo JP, Zhang LP, Yang SL, Roberts MF, Phillipson JD.

Yao Xue Xue Bao. 2009 Feb;44(2):150-3. Chinese.

PMID:
19408684
9.

Novel α3β4 nicotinic acetylcholine receptor-selective ligands. Discovery, structure-activity studies, and pharmacological evaluation.

Zaveri N, Jiang F, Olsen C, Polgar W, Toll L.

J Med Chem. 2010 Nov 25;53(22):8187-91. doi: 10.1021/jm1006148. Epub 2010 Oct 27.

10.

Conformational mobility of immobilized alpha3beta2, alpha3beta4, alpha4beta2, and alpha4beta4 nicotinic acetylcholine receptors.

Moaddel R, Jozwiak K, Whittington K, Wainer IW.

Anal Chem. 2005 Feb 1;77(3):895-901.

PMID:
15679359
11.

Roles of nicotinic acetylcholine receptor beta subunits in function of human alpha4-containing nicotinic receptors.

Wu J, Liu Q, Yu K, Hu J, Kuo YP, Segerberg M, St John PA, Lukas RJ.

J Physiol. 2006 Oct 1;576(Pt 1):103-18. Epub 2006 Jul 6.

12.

Long-term exposure to the new nicotinic antagonist 1,2-bisN-cytisinylethane upregulates nicotinic receptor subtypes of SH-SY5Y human neuroblastoma cells.

Riganti L, Matteoni C, Di Angelantonio S, Nistri A, Gaimarri A, Sparatore F, Canu-Boido C, Clementi F, Gotti C.

Br J Pharmacol. 2005 Dec;146(8):1096-109.

13.

Alkaloids indolizidine 235B', quinolizidine 1-epi-207I, and the tricyclic 205B are potent and selective noncompetitive inhibitors of nicotinic acetylcholine receptors.

Tsuneki H, You Y, Toyooka N, Kagawa S, Kobayashi S, Sasaoka T, Nemoto H, Kimura I, Dani JA.

Mol Pharmacol. 2004 Oct;66(4):1061-9. Epub 2004 Jul 16.

14.

Marine alkaloids (-)-pictamine and (-)-lepadin B block neuronal nicotinic acetylcholine receptors.

Tsuneki H, You Y, Toyooka N, Sasaoka T, Nemoto H, Dani JA, Kimura I.

Biol Pharm Bull. 2005 Apr;28(4):611-4.

15.

Erythrina mulungu alkaloids are potent inhibitors of neuronal nicotinic receptor currents in mammalian cells.

Setti-Perdigão P, Serrano MA, Flausino OA Jr, Bolzani VS, Guimarães MZ, Castro NG.

PLoS One. 2013 Dec 13;8(12):e82726. doi: 10.1371/journal.pone.0082726. eCollection 2013.

16.

AT-1001: a high affinity and selective α3β4 nicotinic acetylcholine receptor antagonist blocks nicotine self-administration in rats.

Toll L, Zaveri NT, Polgar WE, Jiang F, Khroyan TV, Zhou W, Xie XS, Stauber GB, Costello MR, Leslie FM.

Neuropsychopharmacology. 2012 May;37(6):1367-76. doi: 10.1038/npp.2011.322. Epub 2012 Jan 25.

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Carbamoylcholine homologs: novel and potent agonists at neuronal nicotinic acetylcholine receptors.

Jensen AA, Mikkelsen I, Frølund B, Bräuner-Osborne H, Falch E, Krogsgaard-Larsen P.

Mol Pharmacol. 2003 Oct;64(4):865-75.

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