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Items: 1 to 20 of 122

1.

Deletion of Fn14 receptor protects from right heart fibrosis and dysfunction.

Novoyatleva T, Schymura Y, Janssen W, Strobl F, Swiercz JM, Patra C, Posern G, Wietelmann A, Zheng TS, Schermuly RT, Engel FB.

Basic Res Cardiol. 2013 Mar;108(2):325. doi: 10.1007/s00395-012-0325-x. Epub 2013 Jan 17.

2.

TWEAK/Fn14 axis is a positive regulator of cardiac hypertrophy.

Novoyatleva T, Janssen W, Wietelmann A, Schermuly RT, Engel FB.

Cytokine. 2013 Oct;64(1):43-5. doi: 10.1016/j.cyto.2013.05.009. Epub 2013 Jun 10.

PMID:
23764551
3.

Allogenic stem cell therapy improves right ventricular function by improving lung pathology in rats with pulmonary hypertension.

Umar S, de Visser YP, Steendijk P, Schutte CI, Laghmani el H, Wagenaar GT, Bax WH, Mantikou E, Pijnappels DA, Atsma DE, Schalij MJ, van der Wall EE, van der Laarse A.

Am J Physiol Heart Circ Physiol. 2009 Nov;297(5):H1606-16. doi: 10.1152/ajpheart.00590.2009. Epub 2009 Sep 25.

4.

Adverse biventricular remodeling in isolated right ventricular hypertension is mediated by increased transforming growth factor-β1 signaling and is abrogated by angiotensin receptor blockade.

Friedberg MK, Cho MY, Li J, Assad RS, Sun M, Rohailla S, Honjo O, Apitz C, Redington AN.

Am J Respir Cell Mol Biol. 2013 Dec;49(6):1019-28. doi: 10.1165/rcmb.2013-0149OC.

PMID:
23841477
5.

Rutaecarpine attenuates hypoxia-induced right ventricular remodeling in rats.

Li WQ, Li XH, Du J, Zhang W, Li D, Xiong XM, Li YJ.

Naunyn Schmiedebergs Arch Pharmacol. 2016 Jul;389(7):757-67. doi: 10.1007/s00210-016-1240-8. Epub 2016 Apr 6.

PMID:
27052575
6.

Intralipid prevents and rescues fatal pulmonary arterial hypertension and right ventricular failure in rats.

Umar S, Nadadur RD, Li J, Maltese F, Partownavid P, van der Laarse A, Eghbali M.

Hypertension. 2011 Sep;58(3):512-8. doi: 10.1161/HYPERTENSIONAHA.110.168781. Epub 2011 Jul 11.

7.

Tumour necrosis factor-like weak inducer of apoptosis (TWEAK) and its receptor Fn14 during cardiac remodelling in rats.

Mustonen E, Säkkinen H, Tokola H, Isopoussu E, Aro J, Leskinen H, Ruskoaho H, Rysä J.

Acta Physiol (Oxf). 2010 May;199(1):11-22. doi: 10.1111/j.1748-1716.2010.02080.x. Epub 2010 Jan 16.

PMID:
20082609
8.

Time course of right ventricular pressure-overload induced myocardial fibrosis: relationship to changes in fibroblast postsynthetic procollagen processing.

Baicu CF, Li J, Zhang Y, Kasiganesan H, Cooper G 4th, Zile MR, Bradshaw AD.

Am J Physiol Heart Circ Physiol. 2012 Nov 1;303(9):H1128-34. doi: 10.1152/ajpheart.00482.2012. Epub 2012 Aug 31.

9.

Biventricular structural and functional responses to aortic constriction in a rabbit model of chronic right ventricular pressure overload.

Apitz C, Honjo O, Humpl T, Li J, Assad RS, Cho MY, Hong J, Friedberg MK, Redington AN.

J Thorac Cardiovasc Surg. 2012 Dec;144(6):1494-501. doi: 10.1016/j.jtcvs.2012.06.027. Epub 2012 Jul 18.

10.

Rho-kinase inhibition alleviates pulmonary hypertension in transgenic mice expressing a dominant-negative type II bone morphogenetic protein receptor gene.

Yasuda T, Tada Y, Tanabe N, Tatsumi K, West J.

Am J Physiol Lung Cell Mol Physiol. 2011 Nov;301(5):L667-74. doi: 10.1152/ajplung.00423.2010. Epub 2011 Aug 19.

11.

Carvedilol improves biventricular fibrosis and function in experimental pulmonary hypertension.

Okumura K, Kato H, Honjo O, Breitling S, Kuebler WM, Sun M, Friedberg MK.

J Mol Med (Berl). 2015 Jun;93(6):663-74. doi: 10.1007/s00109-015-1251-9. Epub 2015 Jan 18.

PMID:
25595602
12.

Right ventricular diastolic impairment in patients with pulmonary arterial hypertension.

Rain S, Handoko ML, Trip P, Gan CT, Westerhof N, Stienen GJ, Paulus WJ, Ottenheijm CA, Marcus JT, Dorfmüller P, Guignabert C, Humbert M, Macdonald P, Dos Remedios C, Postmus PE, Saripalli C, Hidalgo CG, Granzier HL, Vonk-Noordegraaf A, van der Velden J, de Man FS.

Circulation. 2013 Oct 29;128(18):2016-25, 1-10. doi: 10.1161/CIRCULATIONAHA.113.001873. Epub 2013 Sep 20.

13.

Suppression of histone deacetylases worsens right ventricular dysfunction after pulmonary artery banding in rats.

Bogaard HJ, Mizuno S, Hussaini AA, Toldo S, Abbate A, Kraskauskas D, Kasper M, Natarajan R, Voelkel NF.

Am J Respir Crit Care Med. 2011 May 15;183(10):1402-10. doi: 10.1164/rccm.201007-1106OC. Epub 2011 Feb 4.

PMID:
21297075
14.

Crucial role of rho-kinase in pressure overload-induced right ventricular hypertrophy and dysfunction in mice.

Ikeda S, Satoh K, Kikuchi N, Miyata S, Suzuki K, Omura J, Shimizu T, Kobayashi K, Kobayashi K, Fukumoto Y, Sakata Y, Shimokawa H.

Arterioscler Thromb Vasc Biol. 2014 Jun;34(6):1260-71. doi: 10.1161/ATVBAHA.114.303320. Epub 2014 Mar 27.

15.

TWEAK/Fn14 promotes the proliferation and collagen synthesis of rat cardiac fibroblasts via the NF-кB pathway.

Chen HN, Wang DJ, Ren MY, Wang QL, Sui SJ.

Mol Biol Rep. 2012 Aug;39(8):8231-41. doi: 10.1007/s11033-012-1671-3. Epub 2012 May 4.

PMID:
22555979
16.

Reducing endoglin activity limits calcineurin and TRPC-6 expression and improves survival in a mouse model of right ventricular pressure overload.

Kapur NK, Qiao X, Paruchuri V, Mackey EE, Daly GH, Ughreja K, Morine KJ, Levine J, Aronovitz MJ, Hill NS, Jaffe IZ, Letarte M, Karas RH.

J Am Heart Assoc. 2014 Jul 11;3(4). pii: e000965. doi: 10.1161/JAHA.114.000965. Erratum in: J Am Heart Assoc. 2014 Aug;3(4):e000419. Ughreja, Kesahn [Corrected to Ughreja, Kishan].

17.

Antioxidant treatment attenuates pulmonary arterial hypertension-induced heart failure.

Redout EM, van der Toorn A, Zuidwijk MJ, van de Kolk CW, van Echteld CJ, Musters RJ, van Hardeveld C, Paulus WJ, Simonides WS.

Am J Physiol Heart Circ Physiol. 2010 Mar;298(3):H1038-47. doi: 10.1152/ajpheart.00097.2009. Epub 2010 Jan 8.

18.

Bosentan attenuates right ventricular hypertrophy and fibrosis in normobaric hypoxia model of pulmonary hypertension.

Choudhary G, Troncales F, Martin D, Harrington EO, Klinger JR.

J Heart Lung Transplant. 2011 Jul;30(7):827-33. doi: 10.1016/j.healun.2011.03.010. Epub 2011 May 8.

19.

Cardiomyocyte-specific overexpression of HEXIM1 prevents right ventricular hypertrophy in hypoxia-induced pulmonary hypertension in mice.

Yoshikawa N, Shimizu N, Maruyama T, Sano M, Matsuhashi T, Fukuda K, Kataoka M, Satoh T, Ojima H, Sawai T, Morimoto C, Kuribara A, Hosono O, Tanaka H.

PLoS One. 2012;7(12):e52522. doi: 10.1371/journal.pone.0052522. Epub 2012 Dec 31.

20.

Differential responses of the right ventricle to abnormal loading conditions in mice: pressure vs. volume load.

Bartelds B, Borgdorff MA, Smit-van Oosten A, Takens J, Boersma B, Nederhoff MG, Elzenga NJ, van Gilst WH, De Windt LJ, Berger RM.

Eur J Heart Fail. 2011 Dec;13(12):1275-82. doi: 10.1093/eurjhf/hfr134. Epub 2011 Oct 24.

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