Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 541

1.

Synthetic tau fibrils mediate transmission of neurofibrillary tangles in a transgenic mouse model of Alzheimer's-like tauopathy.

Iba M, Guo JL, McBride JD, Zhang B, Trojanowski JQ, Lee VM.

J Neurosci. 2013 Jan 16;33(3):1024-37. doi: 10.1523/JNEUROSCI.2642-12.2013.

2.

Unique pathological tau conformers from Alzheimer's brains transmit tau pathology in nontransgenic mice.

Guo JL, Narasimhan S, Changolkar L, He Z, Stieber A, Zhang B, Gathagan RJ, Iba M, McBride JD, Trojanowski JQ, Lee VM.

J Exp Med. 2016 Nov 14;213(12):2635-2654. Epub 2016 Oct 17.

3.

A novel transgenic mouse expressing double mutant tau driven by its natural promoter exhibits tauopathy characteristics.

Rosenmann H, Grigoriadis N, Eldar-Levy H, Avital A, Rozenstein L, Touloumi O, Behar L, Ben-Hur T, Avraham Y, Berry E, Segal M, Ginzburg I, Abramsky O.

Exp Neurol. 2008 Jul;212(1):71-84. doi: 10.1016/j.expneurol.2008.03.007. Epub 2008 Mar 21.

PMID:
18490011
4.

Tau pathology spread in PS19 tau transgenic mice following locus coeruleus (LC) injections of synthetic tau fibrils is determined by the LC's afferent and efferent connections.

Iba M, McBride JD, Guo JL, Zhang B, Trojanowski JQ, Lee VM.

Acta Neuropathol. 2015 Sep;130(3):349-62. doi: 10.1007/s00401-015-1458-4. Epub 2015 Jul 7.

5.

GFP-Mutant Human Tau Transgenic Mice Develop Tauopathy Following CNS Injections of Alzheimer's Brain-Derived Pathological Tau or Synthetic Mutant Human Tau Fibrils.

Gibbons GS, Banks RA, Kim B, Xu H, Changolkar L, Leight SN, Riddle DM, Li C, Gathagan RJ, Brown HJ, Zhang B, Trojanowski JQ, Lee VM.

J Neurosci. 2017 Nov 22;37(47):11485-11494. doi: 10.1523/JNEUROSCI.2393-17.2017. Epub 2017 Oct 6.

6.

Differential induction and spread of tau pathology in young PS19 tau transgenic mice following intracerebral injections of pathological tau from Alzheimer's disease or corticobasal degeneration brains.

Boluda S, Iba M, Zhang B, Raible KM, Lee VM, Trojanowski JQ.

Acta Neuropathol. 2015 Feb;129(2):221-37. doi: 10.1007/s00401-014-1373-0. Epub 2014 Dec 24.

7.

Novel human neuronal tau model exhibiting neurofibrillary tangles and transcellular propagation.

Reilly P, Winston CN, Baron KR, Trejo M, Rockenstein EM, Akers JC, Kfoury N, Diamond M, Masliah E, Rissman RA, Yuan SH.

Neurobiol Dis. 2017 Oct;106:222-234. doi: 10.1016/j.nbd.2017.06.005. Epub 2017 Jun 10.

PMID:
28610892
8.

Age-dependent induction of congophilic neurofibrillary tau inclusions in tau transgenic mice.

Ishihara T, Zhang B, Higuchi M, Yoshiyama Y, Trojanowski JQ, Lee VM.

Am J Pathol. 2001 Feb;158(2):555-62.

9.

Intracerebral injection of preformed synthetic tau fibrils initiates widespread tauopathy and neuronal loss in the brains of tau transgenic mice.

Peeraer E, Bottelbergs A, Van Kolen K, Stancu IC, Vasconcelos B, Mahieu M, Duytschaever H, Ver Donck L, Torremans A, Sluydts E, Van Acker N, Kemp JA, Mercken M, Brunden KR, Trojanowski JQ, Dewachter I, Lee VM, Moechars D.

Neurobiol Dis. 2015 Jan;73:83-95. doi: 10.1016/j.nbd.2014.08.032. Epub 2014 Sep 16.

10.

[Neuropathology of tauopathy].

Yoshida M.

Brain Nerve. 2013 Dec;65(12):1445-58. Review. Japanese.

PMID:
24323931
11.

Truncated tau expression levels determine life span of a rat model of tauopathy without causing neuronal loss or correlating with terminal neurofibrillary tangle load.

Koson P, Zilka N, Kovac A, Kovacech B, Korenova M, Filipcik P, Novak M.

Eur J Neurosci. 2008 Jul;28(2):239-46. doi: 10.1111/j.1460-9568.2008.06329.x.

PMID:
18702695
12.

Passive immunization with phospho-tau antibodies reduces tau pathology and functional deficits in two distinct mouse tauopathy models.

Sankaranarayanan S, Barten DM, Vana L, Devidze N, Yang L, Cadelina G, Hoque N, DeCarr L, Keenan S, Lin A, Cao Y, Snyder B, Zhang B, Nitla M, Hirschfeld G, Barrezueta N, Polson C, Wes P, Rangan VS, Cacace A, Albright CF, Meredith J Jr, Trojanowski JQ, Lee VM, Brunden KR, Ahlijanian M.

PLoS One. 2015 May 1;10(5):e0125614. doi: 10.1371/journal.pone.0125614. eCollection 2015.

13.

Hypersialylation is a common feature of neurofibrillary tangles and granulovacuolar degenerations in Alzheimer's disease and tauopathy brains.

Nagamine S, Yamazaki T, Makioka K, Fujita Y, Ikeda M, Takatama M, Okamoto K, Yokoo H, Ikeda Y.

Neuropathology. 2016 Aug;36(4):333-45. doi: 10.1111/neup.12277. Epub 2015 Dec 21.

PMID:
26685795
14.

Sources of extracellular tau and its signaling.

Avila J, Simón D, Díaz-Hernández M, Pintor J, Hernández F.

J Alzheimers Dis. 2014;40 Suppl 1:S7-S15. doi: 10.3233/JAD-131832. Review.

PMID:
24531154
15.

A{beta} accelerates the spatiotemporal progression of tau pathology and augments tau amyloidosis in an Alzheimer mouse model.

Hurtado DE, Molina-Porcel L, Iba M, Aboagye AK, Paul SM, Trojanowski JQ, Lee VM.

Am J Pathol. 2010 Oct;177(4):1977-88. doi: 10.2353/ajpath.2010.100346. Epub 2010 Aug 27.

16.

Propagation of Tau Aggregates and Neurodegeneration.

Goedert M, Eisenberg DS, Crowther RA.

Annu Rev Neurosci. 2017 Jul 25;40:189-210. doi: 10.1146/annurev-neuro-072116-031153. Review.

PMID:
28772101
17.

Tau as a therapeutic target for Alzheimer's disease.

Boutajangout A, Sigurdsson EM, Krishnamurthy PK.

Curr Alzheimer Res. 2011 Sep;8(6):666-77. Review.

18.

Seeding of normal Tau by pathological Tau conformers drives pathogenesis of Alzheimer-like tangles.

Guo JL, Lee VM.

J Biol Chem. 2011 Apr 29;286(17):15317-31. doi: 10.1074/jbc.M110.209296. Epub 2011 Mar 3.

19.

A seeding based cellular assay of tauopathy.

Xu Y, Martini-Stoica H, Zheng H.

Mol Neurodegener. 2016 Apr 26;11:32. doi: 10.1186/s13024-016-0100-9.

20.

Mechanisms of tau self-aggregation and neurotoxicity.

Farías G, Cornejo A, Jiménez J, Guzmán L, Maccioni RB.

Curr Alzheimer Res. 2011 Sep;8(6):608-14. Review.

PMID:
21605046

Supplemental Content

Support Center