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Items: 1 to 20 of 286


Transcription of the herpes simplex virus latency-associated transcript promotes the formation of facultative heterochromatin on lytic promoters.

Cliffe AR, Garber DA, Knipe DM.

J Virol. 2009 Aug;83(16):8182-90. doi: 10.1128/JVI.00712-09. Epub 2009 Jun 10.


The polycomb group protein Bmi1 binds to the herpes simplex virus 1 latent genome and maintains repressive histone marks during latency.

Kwiatkowski DL, Thompson HW, Bloom DC.

J Virol. 2009 Aug;83(16):8173-81. doi: 10.1128/JVI.00686-09. Epub 2009 Jun 10.


Herpesviral ICP0 Protein Promotes Two Waves of Heterochromatin Removal on an Early Viral Promoter during Lytic Infection.

Lee JS, Raja P, Knipe DM.

MBio. 2016 Jan 12;7(1):e02007-15. doi: 10.1128/mBio.02007-15.


Herpesviral latency-associated transcript gene promotes assembly of heterochromatin on viral lytic-gene promoters in latent infection.

Wang QY, Zhou C, Johnson KE, Colgrove RC, Coen DM, Knipe DM.

Proc Natl Acad Sci U S A. 2005 Nov 1;102(44):16055-9. Epub 2005 Oct 24.


Role of polycomb proteins in regulating HSV-1 latency.

Watson Z, Dhummakupt A, Messer H, Phelan D, Bloom D.

Viruses. 2013 Jul 15;5(7):1740-57. doi: 10.3390/v5071740. Review.


Polycomb repressive complex 2 silences human cytomegalovirus transcription in quiescent infection models.

Abraham CG, Kulesza CA.

J Virol. 2013 Dec;87(24):13193-205. doi: 10.1128/JVI.02420-13. Epub 2013 Sep 25.


CCCTC-Binding Factor Acts as a Heterochromatin Barrier on Herpes Simplex Viral Latent Chromatin and Contributes to Poised Latent Infection.

Lee JS, Raja P, Pan D, Pesola JM, Coen DM, Knipe DM.

MBio. 2018 Feb 6;9(1). pii: e02372-17. doi: 10.1128/mBio.02372-17.


A novel selective LSD1/KDM1A inhibitor epigenetically blocks herpes simplex virus lytic replication and reactivation from latency.

Liang Y, Quenelle D, Vogel JL, Mascaro C, Ortega A, Kristie TM.

MBio. 2013 Feb 5;4(1):e00558-12. doi: 10.1128/mBio.00558-12.


Epigenetic analysis of KSHV latent and lytic genomes.

Toth Z, Maglinte DT, Lee SH, Lee HR, Wong LY, Brulois KF, Lee S, Buckley JD, Laird PW, Marquez VE, Jung JU.

PLoS Pathog. 2010 Jul 22;6(7):e1001013. doi: 10.1371/journal.ppat.1001013.


CTCF Binding Sites in the Herpes Simplex Virus 1 Genome Display Site-Specific CTCF Occupation, Protein Recruitment, and Insulator Function.

Washington SD, Musarrat F, Ertel MK, Backes GL, Neumann DM.

J Virol. 2018 Mar 28;92(8). pii: e00156-18. doi: 10.1128/JVI.00156-18. Print 2018 Apr 15.


Chromatin control of herpes simplex virus lytic and latent infection.

Knipe DM, Cliffe A.

Nat Rev Microbiol. 2008 Mar;6(3):211-21. doi: 10.1038/nrmicro1794. Review.


Long-term promoter activity during herpes simplex virus latency.

Lokensgard JR, Bloom DC, Dobson AT, Feldman LT.

J Virol. 1994 Nov;68(11):7148-58.


A Herpesviral Lytic Protein Regulates the Structure of Latent Viral Chromatin.

Raja P, Lee JS, Pan D, Pesola JM, Coen DM, Knipe DM.

MBio. 2016 May 17;7(3). pii: e00633-16. doi: 10.1128/mBio.00633-16.


Epigenetic regulation of latent HSV-1 gene expression.

Bloom DC, Giordani NV, Kwiatkowski DL.

Biochim Biophys Acta. 2010 Mar-Apr;1799(3-4):246-56. doi: 10.1016/j.bbagrm.2009.12.001. Epub 2010 Jan 4. Review.


Transcription of the herpes simplex virus 1 genome during productive and quiescent infection of neuronal and nonneuronal cells.

Harkness JM, Kader M, DeLuca NA.

J Virol. 2014 Jun;88(12):6847-61. doi: 10.1128/JVI.00516-14. Epub 2014 Apr 9.


Neuronal control of herpes simplex virus latency.

Tenser RB, Edris WA, Hay KA.

Virology. 1993 Aug;195(2):337-47.


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