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Items: 1 to 20 of 113

1.

Phenelzine mitochondrial functional preservation and neuroprotection after traumatic brain injury related to scavenging of the lipid peroxidation-derived aldehyde 4-hydroxy-2-nonenal.

Singh IN, Gilmer LK, Miller DM, Cebak JE, Wang JA, Hall ED.

J Cereb Blood Flow Metab. 2013 Apr;33(4):593-9. doi: 10.1038/jcbfm.2012.211. Epub 2013 Jan 16.

2.
3.

Mitochondrial protection after traumatic brain injury by scavenging lipid peroxyl radicals.

Mustafa AG, Singh IN, Wang J, Carrico KM, Hall ED.

J Neurochem. 2010 Jul;114(1):271-80. doi: 10.1111/j.1471-4159.2010.06749.x. Epub 2010 Apr 16.

4.

Progesterone protects mitochondrial function in a rat model of pediatric traumatic brain injury.

Robertson CL, Saraswati M.

J Bioenerg Biomembr. 2015 Apr;47(1-2):43-51. doi: 10.1007/s10863-014-9585-5. Epub 2014 Oct 28.

PMID:
25348484
5.

Lipid peroxidation-derived reactive aldehydes directly and differentially impair spinal cord and brain mitochondrial function.

Vaishnav RA, Singh IN, Miller DM, Hall ED.

J Neurotrauma. 2010 Jul;27(7):1311-20. doi: 10.1089/neu.2009.1172.

6.

Aldehyde load in ischemia-reperfusion brain injury: neuroprotection by neutralization of reactive aldehydes with phenelzine.

Wood PL, Khan MA, Moskal JR, Todd KG, Tanay VA, Baker G.

Brain Res. 2006 Nov 29;1122(1):184-90. Epub 2006 Oct 5.

PMID:
17026969
7.

Post-Injury Administration of Mitochondrial Uncouplers Increases Tissue Sparing and Improves Behavioral Outcome following Traumatic Brain Injury in Rodents.

Pandya JD, Pauly JR, Nukala VN, Sebastian AH, Day KM, Korde AS, Maragos WF, Hall ED, Sullivan PG.

J Neurotrauma. 2007 May;24(5):798-811.

PMID:
17518535
8.

Nrf2-ARE activator carnosic acid decreases mitochondrial dysfunction, oxidative damage and neuronal cytoskeletal degradation following traumatic brain injury in mice.

Miller DM, Singh IN, Wang JA, Hall ED.

Exp Neurol. 2015 Feb;264:103-10. doi: 10.1016/j.expneurol.2014.11.008. Epub 2014 Nov 26.

9.

Administration of the Nrf2-ARE activators sulforaphane and carnosic acid attenuates 4-hydroxy-2-nonenal-induced mitochondrial dysfunction ex vivo.

Miller DM, Singh IN, Wang JA, Hall ED.

Free Radic Biol Med. 2013 Apr;57:1-9. doi: 10.1016/j.freeradbiomed.2012.12.011. Epub 2012 Dec 27.

10.

Cyclosporin A preserves mitochondrial function after traumatic brain injury in the immature rat and piglet.

Kilbaugh TJ, Bhandare S, Lorom DH, Saraswati M, Robertson CL, Margulies SS.

J Neurotrauma. 2011 May;28(5):763-74. doi: 10.1089/neu.2010.1635. Epub 2011 Apr 12.

11.

4-Hydroxy-2(E)-nonenal inhibits CNS mitochondrial respiration at multiple sites.

Picklo MJ, Amarnath V, McIntyre JO, Graham DG, Montine TJ.

J Neurochem. 1999 Apr;72(4):1617-24.

12.

Cyclosporin A attenuates acute mitochondrial dysfunction following traumatic brain injury.

Sullivan PG, Thompson MB, Scheff SW.

Exp Neurol. 1999 Nov;160(1):226-34.

PMID:
10630207
13.

The optimal dosage and window of opportunity to maintain mitochondrial homeostasis following traumatic brain injury using the uncoupler FCCP.

Pandya JD, Pauly JR, Sullivan PG.

Exp Neurol. 2009 Aug;218(2):381-9. doi: 10.1016/j.expneurol.2009.05.023. Epub 2009 May 27.

PMID:
19477175
14.

Propofol ameliorates calpain-induced collapsin response mediator protein-2 proteolysis in traumatic brain injury in rats.

Yu Y, Jian MY, Wang YZ, Han RQ.

Chin Med J (Engl). 2015 Apr 5;128(7):919-27. doi: 10.4103/0366-6999.154298.

15.

Congeners of N(alpha)-acetyl-L-cysteine but not aminoguanidine act as neuroprotectants from the lipid peroxidation product 4-hydroxy-2-nonenal.

Neely MD, Zimmerman L, Picklo MJ, Ou JJ, Morales CR, Montine KS, Amaranth V, Montine TJ.

Free Radic Biol Med. 2000 Nov 15;29(10):1028-36.

PMID:
11084291
16.

Trans-4-oxo-2-nonenal potently alters mitochondrial function.

Picklo MJ, Azenkeng A, Hoffmann MR.

Free Radic Biol Med. 2011 Jan 15;50(2):400-7. doi: 10.1016/j.freeradbiomed.2010.11.014. Epub 2010 Nov 16.

PMID:
21092757
17.

Time courses of post-injury mitochondrial oxidative damage and respiratory dysfunction and neuronal cytoskeletal degradation in a rat model of focal traumatic brain injury.

Hill RL, Singh IN, Wang JA, Hall ED.

Neurochem Int. 2017 Mar 23. pii: S0197-0186(17)30160-2. doi: 10.1016/j.neuint.2017.03.015. [Epub ahead of print]

PMID:
28342966
18.

4-hydroxynonenal, a lipid peroxidation product, impairs glutamate transport in cortical astrocytes.

Blanc EM, Keller JN, Fernandez S, Mattson MP.

Glia. 1998 Feb;22(2):149-60.

PMID:
9537835
19.

Mitochondrial dysfunction in aging rat brain following transient global ischemia.

Xu K, Puchowicz MA, Sun X, LaManna JC.

Adv Exp Med Biol. 2008;614:379-86. doi: 10.1007/978-0-387-74911-2_42.

20.

Pharmacological inhibition of lipid peroxidation attenuates calpain-mediated cytoskeletal degradation after traumatic brain injury.

Mustafa AG, Wang JA, Carrico KM, Hall ED.

J Neurochem. 2011 May;117(3):579-88. doi: 10.1111/j.1471-4159.2011.07228.x. Epub 2011 Mar 22.

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