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FOXP3 regulates sensitivity of cancer cells to irradiation by transcriptional repression of BRCA1.

Li W, Katoh H, Wang L, Yu X, Du Z, Yan X, Zheng P, Liu Y.

Cancer Res. 2013 Apr 1;73(7):2170-80. doi: 10.1158/0008-5472.CAN-12-2481. Epub 2013 Jan 14.


Hypoxia-induced down-regulation of BRCA1 expression by E2Fs.

Bindra RS, Gibson SL, Meng A, Westermark U, Jasin M, Pierce AJ, Bristow RG, Classon MK, Glazer PM.

Cancer Res. 2005 Dec 15;65(24):11597-604.


Downregulation of Ezh2 methyltransferase by FOXP3: new insight of FOXP3 into chromatin remodeling?

Shen Z, Chen L, Yang X, Zhao Y, Pier E, Zhang X, Yang X, Xiong Y.

Biochim Biophys Acta. 2013 Oct;1833(10):2190-200. doi: 10.1016/j.bbamcr.2013.05.014. Epub 2013 May 17.


BRCA1 represses amphiregulin gene expression.

Lamber EP, Horwitz AA, Parvin JD.

Cancer Res. 2010 Feb 1;70(3):996-1005. doi: 10.1158/0008-5472.CAN-09-2842. Epub 2010 Jan 26.


BRCA1 transcriptionally regulates genes associated with the basal-like phenotype in breast cancer.

Gorski JJ, James CR, Quinn JE, Stewart GE, Staunton KC, Buckley NE, McDyer FA, Kennedy RD, Wilson RH, Mullan PB, Harkin DP.

Breast Cancer Res Treat. 2010 Aug;122(3):721-31. doi: 10.1007/s10549-009-0565-0. Epub 2009 Oct 31.


RNA-seq profiling of a radiation resistant and radiation sensitive prostate cancer cell line highlights opposing regulation of DNA repair and targets for radiosensitization.

Young A, Berry R, Holloway AF, Blackburn NB, Dickinson JL, Skala M, Phillips JL, Brettingham-Moore KH.

BMC Cancer. 2014 Nov 4;14:808. doi: 10.1186/1471-2407-14-808.


Transcriptional regulation of the human thromboxane A2 receptor gene by Wilms' tumor (WT)1 and hypermethylated in cancer (HIC) 1 in prostate and breast cancers.

Keating GL, Reid HM, Eivers SB, Mulvaney EP, Kinsella BT.

Biochim Biophys Acta. 2014 Jun;1839(6):476-92. doi: 10.1016/j.bbagrm.2014.04.010. Epub 2014 Apr 18.


RUNX1 and FOXP3 interplay regulates expression of breast cancer related genes.

Recouvreux MS, Grasso EN, Echeverria PC, Rocha-Viegas L, Castilla LH, Schere-Levy C, Tocci JM, Kordon EC, Rubinstein N.

Oncotarget. 2016 Feb 9;7(6):6552-65. doi: 10.18632/oncotarget.6771.


Identification of a tumor suppressor relay between the FOXP3 and the Hippo pathways in breast and prostate cancers.

Li W, Wang L, Katoh H, Liu R, Zheng P, Liu Y.

Cancer Res. 2011 Mar 15;71(6):2162-71. doi: 10.1158/0008-5472.CAN-10-3268. Epub 2011 Jan 28.


BRCA1 expression restores radiation resistance in BRCA1-defective cancer cells through enhancement of transcription-coupled DNA repair.

Abbott DW, Thompson ME, Robinson-Benion C, Tomlinson G, Jensen RA, Holt JT.

J Biol Chem. 1999 Jun 25;274(26):18808-12.


Characterization of a negative transcriptional element in the BRCA1 promoter.

MacDonald G, Stramwasser M, Mueller CR.

Breast Cancer Res. 2007;9(4):R49.


Genetic analysis of BRCA1 function in a defined tumor cell line.

Scully R, Ganesan S, Vlasakova K, Chen J, Socolovsky M, Livingston DM.

Mol Cell. 1999 Dec;4(6):1093-9.


Embryonic mammary signature subsets are activated in Brca1-/- and basal-like breast cancers.

Zvelebil M, Oliemuller E, Gao Q, Wansbury O, Mackay A, Kendrick H, Smalley MJ, Reis-Filho JS, Howard BA.

Breast Cancer Res. 2013 Mar 18;15(2):R25. doi: 10.1186/bcr3403.


c-Myc activates BRCA1 gene expression through distal promoter elements in breast cancer cells.

Chen Y, Xu J, Borowicz S, Collins C, Huo D, Olopade OI.

BMC Cancer. 2011 Jun 13;11:246. doi: 10.1186/1471-2407-11-246.


Therapeutic exploitation of tumor cell defects in homologous recombination.

Powell SN, Kachnic LA.

Anticancer Agents Med Chem. 2008 May;8(4):448-60. Review.


Hydrocortisone down-regulates the tumor suppressor gene BRCA1 in mammary cells: a possible molecular link between stress and breast cancer.

Antonova L, Mueller CR.

Genes Chromosomes Cancer. 2008 Apr;47(4):341-52. doi: 10.1002/gcc.20538.


Tumor-specific adenovirus-mediated PUMA gene transfer using the survivin promoter enhances radiosensitivity of breast cancer cells in vitro and in vivo.

Wang R, Wang X, Li B, Lin F, Dong K, Gao P, Zhang HZ.

Breast Cancer Res Treat. 2009 Sep;117(1):45-54. doi: 10.1007/s10549-008-0163-6. Epub 2008 Sep 13.


BRCA1 role in the mitigation of radiotoxicity and chromosomal instability through repair of clustered DNA lesions.

Hair JM, Terzoudi GI, Hatzi VI, Lehockey KA, Srivastava D, Wang W, Pantelias GE, Georgakilas AG.

Chem Biol Interact. 2010 Nov 5;188(2):350-8. doi: 10.1016/j.cbi.2010.03.046. Epub 2010 Apr 4. Review.


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