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Items: 1 to 20 of 169

1.

Blockade of B-cell-activating factor signaling enhances hepatic steatosis induced by a high-fat diet and improves insulin sensitivity.

Kawasaki K, Abe M, Tada F, Tokumoto Y, Chen S, Miyake T, Furukawa S, Matsuura B, Hiasa Y, Onji M.

Lab Invest. 2013 Mar;93(3):311-21. doi: 10.1038/labinvest.2012.176. Epub 2013 Jan 14.

2.

B cell-activating factor controls the production of adipokines and induces insulin resistance.

Hamada M, Abe M, Miyake T, Kawasaki K, Tada F, Furukawa S, Matsuura B, Hiasa Y, Onji M.

Obesity (Silver Spring). 2011 Oct;19(10):1915-22. doi: 10.1038/oby.2011.165. Epub 2011 Jun 23.

3.

Dietary capsaicin reduces obesity-induced insulin resistance and hepatic steatosis in obese mice fed a high-fat diet.

Kang JH, Goto T, Han IS, Kawada T, Kim YM, Yu R.

Obesity (Silver Spring). 2010 Apr;18(4):780-7. doi: 10.1038/oby.2009.301. Epub 2009 Oct 1.

4.

SOCS2 deletion protects against hepatic steatosis but worsens insulin resistance in high-fat-diet-fed mice.

Zadjali F, Santana-Farre R, Vesterlund M, Carow B, Mirecki-Garrido M, Hernandez-Hernandez I, Flodström-Tullberg M, Parini P, Rottenberg M, Norstedt G, Fernandez-Perez L, Flores-Morales A.

FASEB J. 2012 Aug;26(8):3282-91. doi: 10.1096/fj.12-205583. Epub 2012 May 4.

PMID:
22562833
5.

Combined effects of rosiglitazone and conjugated linoleic acid on adiposity, insulin sensitivity, and hepatic steatosis in high-fat-fed mice.

Liu LF, Purushotham A, Wendel AA, Belury MA.

Am J Physiol Gastrointest Liver Physiol. 2007 Jun;292(6):G1671-82. Epub 2007 Feb 22.

6.

Interferon regulatory factor 3 constrains IKKβ/NF-κB signaling to alleviate hepatic steatosis and insulin resistance.

Wang XA, Zhang R, She ZG, Zhang XF, Jiang DS, Wang T, Gao L, Deng W, Zhang SM, Zhu LH, Guo S, Chen K, Zhang XD, Liu DP, Li H.

Hepatology. 2014 Mar;59(3):870-85. doi: 10.1002/hep.26751. Epub 2014 Jan 30.

PMID:
24123166
7.

Amelioration of high fat diet induced liver lipogenesis and hepatic steatosis by interleukin-22.

Yang L, Zhang Y, Wang L, Fan F, Zhu L, Li Z, Ruan X, Huang H, Wang Z, Huang Z, Huang Y, Yan X, Chen Y.

J Hepatol. 2010 Aug;53(2):339-47. doi: 10.1016/j.jhep.2010.03.004. Epub 2010 Apr 21.

PMID:
20452699
8.

Loss of regulator of G protein signaling 5 exacerbates obesity, hepatic steatosis, inflammation and insulin resistance.

Deng W, Wang X, Xiao J, Chen K, Zhou H, Shen D, Li H, Tang Q.

PLoS One. 2012;7(1):e30256. doi: 10.1371/journal.pone.0030256. Epub 2012 Jan 17.

9.

Adipose tissue inflammation contributes to short-term high-fat diet-induced hepatic insulin resistance.

Wiedemann MS, Wueest S, Item F, Schoenle EJ, Konrad D.

Am J Physiol Endocrinol Metab. 2013 Aug 1;305(3):E388-95. doi: 10.1152/ajpendo.00179.2013. Epub 2013 Jun 4.

10.

Kupffer cell activation is a causal factor for hepatic insulin resistance.

Lanthier N, Molendi-Coste O, Horsmans Y, van Rooijen N, Cani PD, Leclercq IA.

Am J Physiol Gastrointest Liver Physiol. 2010 Jan;298(1):G107-16. doi: 10.1152/ajpgi.00391.2009. Epub 2009 Oct 29.

11.

Ursodeoxycholic acid improves insulin sensitivity and hepatic steatosis by inducing the excretion of hepatic lipids in high-fat diet-fed KK-Ay mice.

Tsuchida T, Shiraishi M, Ohta T, Sakai K, Ishii S.

Metabolism. 2012 Jul;61(7):944-53. doi: 10.1016/j.metabol.2011.10.023. Epub 2011 Dec 7.

PMID:
22154323
12.

Synthetic FXR agonist GW4064 prevents diet-induced hepatic steatosis and insulin resistance.

Ma Y, Huang Y, Yan L, Gao M, Liu D.

Pharm Res. 2013 May;30(5):1447-57. doi: 10.1007/s11095-013-0986-7. Epub 2013 Feb 1.

13.

Hepatic NF-kappa B essential modulator deficiency prevents obesity-induced insulin resistance but synergizes with high-fat feeding in tumorigenesis.

Wunderlich FT, Luedde T, Singer S, Schmidt-Supprian M, Baumgartl J, Schirmacher P, Pasparakis M, Brüning JC.

Proc Natl Acad Sci U S A. 2008 Jan 29;105(4):1297-302. doi: 10.1073/pnas.0707849104. Epub 2008 Jan 23.

14.

Increased hepatic steatosis and insulin resistance in mice lacking hepatic androgen receptor.

Lin HY, Yu IC, Wang RS, Chen YT, Liu NC, Altuwaijri S, Hsu CL, Ma WL, Jokinen J, Sparks JD, Yeh S, Chang C.

Hepatology. 2008 Jun;47(6):1924-35. doi: 10.1002/hep.22252.

PMID:
18449947
15.

Enhancing liver mitochondrial fatty acid oxidation capacity in obese mice improves insulin sensitivity independently of hepatic steatosis.

Monsénégo J, Mansouri A, Akkaoui M, Lenoir V, Esnous C, Fauveau V, Tavernier V, Girard J, Prip-Buus C.

J Hepatol. 2012 Mar;56(3):632-9. doi: 10.1016/j.jhep.2011.10.008. Epub 2011 Oct 25.

PMID:
22037024
16.

Long-term adaptation of global transcription and metabolism in the liver of high-fat diet-fed C57BL/6J mice.

Do GM, Oh HY, Kwon EY, Cho YY, Shin SK, Park HJ, Jeon SM, Kim E, Hur CG, Park TS, Sung MK, McGregor RA, Choi MS.

Mol Nutr Food Res. 2011 Sep;55 Suppl 2:S173-85. doi: 10.1002/mnfr.201100064. Epub 2011 May 25.

PMID:
21618427
17.

β-catenin links hepatic metabolic zonation with lipid metabolism and diet-induced obesity in mice.

Behari J, Li H, Liu S, Stefanovic-Racic M, Alonso L, O'Donnell CP, Shiva S, Singamsetty S, Watanabe Y, Singh VP, Liu Q.

Am J Pathol. 2014 Dec;184(12):3284-98. doi: 10.1016/j.ajpath.2014.08.022. Epub 2014 Oct 7.

18.

C-C chemokine receptor 2 inhibitor improves diet-induced development of insulin resistance and hepatic steatosis in mice.

Tamura Y, Sugimoto M, Murayama T, Minami M, Nishikaze Y, Ariyasu H, Akamizu T, Kita T, Yokode M, Arai H.

J Atheroscler Thromb. 2010 Mar 31;17(3):219-28. Epub 2010 Feb 24.

19.

Mindin/Spondin 2 inhibits hepatic steatosis, insulin resistance, and obesity via interaction with peroxisome proliferator-activated receptor α in mice.

Zhu LH, Wang A, Luo P, Wang X, Jiang DS, Deng W, Zhang X, Wang T, Liu Y, Gao L, Zhang S, Zhang X, Zhang J, Li H.

J Hepatol. 2014 May;60(5):1046-54. doi: 10.1016/j.jhep.2014.01.011. Epub 2014 Jan 18.

PMID:
24445216
20.

Bardoxolone methyl prevents insulin resistance and the development of hepatic steatosis in mice fed a high-fat diet.

Camer D, Yu Y, Szabo A, Dinh CH, Wang H, Cheng L, Huang XF.

Mol Cell Endocrinol. 2015 Sep 5;412:36-43. doi: 10.1016/j.mce.2015.05.018. Epub 2015 May 19.

PMID:
26001833

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