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Items: 1 to 20 of 129

1.

Beneficial effects of (pGlu-Gln)-CCK-8 on energy intake and metabolism in high fat fed mice are associated with alterations of hypothalamic gene expression.

Montgomery IA, Irwin N, Flatt PR.

Horm Metab Res. 2013 Jun;45(6):471-3. doi: 10.1055/s-0032-1331767. Epub 2013 Jan 11.

PMID:
23315994
2.

Chemical cholecystokinin receptor activation protects against obesity-diabetes in high fat fed mice and has sustainable beneficial effects in genetic ob/ob mice.

Irwin N, Montgomery IA, Moffett RC, Flatt PR.

Biochem Pharmacol. 2013 Jan 1;85(1):81-91. doi: 10.1016/j.bcp.2012.10.008. Epub 2012 Oct 17.

PMID:
23085436
3.

Comparison of independent and combined metabolic effects of chronic treatment with (pGlu-Gln)-CCK-8 and long-acting GLP-1 and GIP mimetics in high fat-fed mice.

Irwin N, Hunter K, Montgomery IA, Flatt PR.

Diabetes Obes Metab. 2013 Jul;15(7):650-9. doi: 10.1111/dom.12079. Epub 2013 Feb 26.

PMID:
23388064
4.

Comparison of the independent and combined metabolic effects of subchronic modulation of CCK and GIP receptor action in obesity-related diabetes.

Irwin N, Montgomery IA, O'Harte FP, Frizelle P, Flatt PR.

Int J Obes (Lond). 2013 Aug;37(8):1058-63. doi: 10.1038/ijo.2012.179. Epub 2012 Nov 20.

PMID:
23164696
5.

Metabolic effects of activation of CCK receptor signaling pathways by twice-daily administration of the enzyme-resistant CCK-8 analog, (pGlu-Gln)-CCK-8, in normal mice.

Irwin N, Frizelle P, O'Harte FP, Flatt PR.

J Endocrinol. 2013 Jan 2;216(1):53-9. doi: 10.1530/JOE-12-0353. Print 2013 Jan.

6.

Comparison of the metabolic effects of sustained CCK1 receptor activation alone and in combination with upregulated leptin signalling in high-fat-fed mice.

Irwin N, Montgomery IA, Flatt PR.

Diabetologia. 2013 Jun;56(6):1425-35. doi: 10.1007/s00125-013-2878-0. Epub 2013 Mar 6.

PMID:
23462797
7.
8.

Beneficial effects of the novel cholecystokinin agonist (pGlu-Gln)-CCK-8 in mouse models of obesity/diabetes.

Irwin N, Frizelle P, Montgomery IA, Moffett RC, O'Harte FPM, Flatt PR.

Diabetologia. 2012 Oct;55(10):2747-2758. doi: 10.1007/s00125-012-2654-6. Epub 2012 Jul 20.

PMID:
22814764
9.

(pGlu-Gln)-CCK-8[mPEG]: a novel, long-acting, mini-PEGylated cholecystokinin (CCK) agonist that improves metabolic status in dietary-induced diabetes.

Irwin N, Frizelle P, O'Harte FP, Flatt PR.

Biochim Biophys Acta. 2013 Aug;1830(8):4009-16. doi: 10.1016/j.bbagen.2013.04.004. Epub 2013 Apr 10.

PMID:
23583730
10.

Effect of feed restriction and supplemental dietary fat on gut peptide and hypothalamic neuropeptide messenger ribonucleic acid concentrations in growing wethers.

Relling AE, Pate JL, Reynolds CK, Loerch SC.

J Anim Sci. 2010 Feb;88(2):737-48. doi: 10.2527/jas.2009-2316. Epub 2009 Nov 6.

PMID:
19897637
11.

Voglibose administration regulates body weight and energy intake in high fat-induced obese mice.

Do HJ, Jin T, Chung JH, Hwang JW, Shin MJ.

Biochem Biophys Res Commun. 2014 Jan 17;443(3):1110-7. doi: 10.1016/j.bbrc.2013.12.120. Epub 2014 Jan 2.

PMID:
24388987
12.

Various dietary fats differentially change the gene expression of neuropeptides involved in body weight regulation in rats.

Dziedzic B, Szemraj J, Bartkowiak J, Walczewska A.

J Neuroendocrinol. 2007 May;19(5):364-73.

PMID:
17425611
13.

Specificity of leptin action on elevated blood glucose levels and hypothalamic neuropeptide Y gene expression in ob/ob mice.

Schwartz MW, Baskin DG, Bukowski TR, Kuijper JL, Foster D, Lasser G, Prunkard DE, Porte D Jr, Woods SC, Seeley RJ, Weigle DS.

Diabetes. 1996 Apr;45(4):531-5.

PMID:
8603777
14.
16.
17.

Activation of hypothalamic NPY, AgRP, MC4R, AND IL-6 mRNA levels in young Lewis rats with early-life diet-induced obesity.

Stofkova A, Skurlova M, Kiss A, Zelezna B, Zorad S, Jurcovicova J.

Endocr Regul. 2009 Jul;43(3):99-106.

PMID:
19817504
18.

Whey protein isolate counteracts the effects of a high-fat diet on energy intake and hypothalamic and adipose tissue expression of energy balance-related genes.

McAllan L, Keane D, Schellekens H, Roche HM, Korpela R, Cryan JF, Nilaweera KN.

Br J Nutr. 2013 Dec 14;110(11):2114-26. doi: 10.1017/S0007114513001396. Epub 2013 Jun 4.

PMID:
23731955
19.

Synergistic metabolic benefits of an exenatide analogue and cholecystokinin in diet-induced obese and leptin-deficient rodents.

Trevaskis JL, Sun C, Athanacio J, D'Souza L, Samant M, Tatarkiewicz K, Griffin PS, Wittmer C, Wang Y, Teng CH, Forood B, Parkes DG, Roth JD.

Diabetes Obes Metab. 2015 Jan;17(1):61-73. doi: 10.1111/dom.12390. Epub 2014 Oct 14.

PMID:
25204356
20.

Adrenalectomy reverses obese phenotype and restores hypothalamic melanocortin tone in leptin-deficient ob/ob mice.

Makimura H, Mizuno TM, Roberts J, Silverstein J, Beasley J, Mobbs CV.

Diabetes. 2000 Nov;49(11):1917-23.

PMID:
11078460

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