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Items: 1 to 20 of 140


Arsenic and the epigenome: interindividual differences in arsenic metabolism related to distinct patterns of DNA methylation.

Bailey KA, Wu MC, Ward WO, Smeester L, Rager JE, García-Vargas G, Del Razo LM, Drobná Z, Stýblo M, Fry RC.

J Biochem Mol Toxicol. 2013 Feb;27(2):106-15. doi: 10.1002/jbt.21462. Epub 2013 Jan 11.


Prenatal arsenic exposure and the epigenome: identifying sites of 5-methylcytosine alterations that predict functional changes in gene expression in newborn cord blood and subsequent birth outcomes.

Rojas D, Rager JE, Smeester L, Bailey KA, Drobná Z, Rubio-Andrade M, Stýblo M, García-Vargas G, Fry RC.

Toxicol Sci. 2015 Jan;143(1):97-106. doi: 10.1093/toxsci/kfu210. Epub 2014 Oct 10.


Gene-specific differential DNA methylation and chronic arsenic exposure in an epigenome-wide association study of adults in Bangladesh.

Argos M, Chen L, Jasmine F, Tong L, Pierce BL, Roy S, Paul-Brutus R, Gamble MV, Harper KN, Parvez F, Rahman M, Rakibuz-Zaman M, Slavkovich V, Baron JA, Graziano JH, Kibriya MG, Ahsan H.

Environ Health Perspect. 2015 Jan;123(1):64-71. doi: 10.1289/ehp.1307884. Epub 2014 Oct 17.


Metabolomic profiles of arsenic (+3 oxidation state) methyltransferase knockout mice: effect of sex and arsenic exposure.

Huang MC, Douillet C, Su M, Zhou K, Wu T, Chen W, Galanko JA, Drobná Z, Saunders RJ, Martin E, Fry RC, Jia W, Stýblo M.

Arch Toxicol. 2017 Jan;91(1):189-202. doi: 10.1007/s00204-016-1676-0. Epub 2016 Feb 16.


Exposure to arsenic in drinking water is associated with increased prevalence of diabetes: a cross-sectional study in the Zimapán and Lagunera regions in Mexico.

Del Razo LM, García-Vargas GG, Valenzuela OL, Castellanos EH, Sánchez-Peña LC, Currier JM, Drobná Z, Loomis D, Stýblo M.

Environ Health. 2011 Aug 24;10:73. doi: 10.1186/1476-069X-10-73.


Prenatal arsenic exposure and the epigenome: altered microRNAs associated with innate and adaptive immune signaling in newborn cord blood.

Rager JE, Bailey KA, Smeester L, Miller SK, Parker JS, Laine JE, Drobná Z, Currier J, Douillet C, Olshan AF, Rubio-Andrade M, Stýblo M, García-Vargas G, Fry RC.

Environ Mol Mutagen. 2014 Apr;55(3):196-208. doi: 10.1002/em.21842. Epub 2013 Dec 10.


Identification of novel gene targets and putative regulators of arsenic-associated DNA methylation in human urothelial cells and bladder cancer.

Rager JE, Tilley SK, Tulenko SE, Smeester L, Ray PD, Yosim A, Currier JM, Ishida MC, González-Horta Mdel C, Sánchez-Ramírez B, Ballinas-Casarrubias L, Gutiérrez-Torres DS, Drobná Z, Del Razo LM, García-Vargas GG, Kim WY, Zhou YH, Wright FA, Stýblo M, Fry RC.

Chem Res Toxicol. 2015 Jun 15;28(6):1144-55. doi: 10.1021/tx500393y. Epub 2015 Jun 3.


Arsenic exposure from drinking water is associated with decreased gene expression and increased DNA methylation in peripheral blood.

Ameer SS, Engström K, Hossain MB, Concha G, Vahter M, Broberg K.

Toxicol Appl Pharmacol. 2017 Apr 15;321:57-66. doi: 10.1016/j.taap.2017.02.019. Epub 2017 Feb 24.


Epigenetic changes in individuals with arsenicosis.

Smeester L, Rager JE, Bailey KA, Guan X, Smith N, García-Vargas G, Del Razo LM, Drobná Z, Kelkar H, Stýblo M, Fry RC.

Chem Res Toxicol. 2011 Feb 18;24(2):165-7. doi: 10.1021/tx1004419. Epub 2011 Feb 4.


Maternal arsenic exposure and DNA damage biomarkers, and the associations with birth outcomes in a general population from Taiwan.

Chou WC, Chung YT, Chen HY, Wang CJ, Ying TH, Chuang CY, Tseng YC, Wang SL.

PLoS One. 2014 Feb 18;9(2):e86398. doi: 10.1371/journal.pone.0086398. eCollection 2014.


Maternal arsenic exposure, arsenic methylation efficiency, and birth outcomes in the Biomarkers of Exposure to ARsenic (BEAR) pregnancy cohort in Mexico.

Laine JE, Bailey KA, Rubio-Andrade M, Olshan AF, Smeester L, Drobná Z, Herring AH, Stýblo M, García-Vargas GG, Fry RC.

Environ Health Perspect. 2015 Feb;123(2):186-92. doi: 10.1289/ehp.1307476. Epub 2014 Oct 17.


Nutritional status has marginal influence on the metabolism of inorganic arsenic in pregnant Bangladeshi women.

Li L, Ekström EC, Goessler W, Lönnerdal B, Nermell B, Yunus M, Rahman A, El Arifeen S, Persson LA, Vahter M.

Environ Health Perspect. 2008 Mar;116(3):315-21. doi: 10.1289/ehp.10639.


Biomarkers of exposure: a case study with inorganic arsenic.

Hughes MF.

Environ Health Perspect. 2006 Nov;114(11):1790-6. Review.


Metabolomic characteristics of arsenic-associated diabetes in a prospective cohort in Chihuahua, Mexico.

Martin E, González-Horta C, Rager J, Bailey KA, Sánchez-Ramírez B, Ballinas-Casarrubias L, Ishida MC, Gutiérrez-Torres DS, Hernández Cerón R, Viniegra Morales D, Baeza Terrazas FA, Saunders RJ, Drobná Z, Mendez MA, Buse JB, Loomis D, Jia W, García-Vargas GG, Del Razo LM, Stýblo M, Fry R.

Toxicol Sci. 2015 Apr;144(2):338-46. doi: 10.1093/toxsci/kfu318. Epub 2015 Jan 9.


Examination of the effects of arsenic on glucose homeostasis in cell culture and animal studies: development of a mouse model for arsenic-induced diabetes.

Paul DS, Hernández-Zavala A, Walton FS, Adair BM, Dedina J, Matousek T, Stýblo M.

Toxicol Appl Pharmacol. 2007 Aug 1;222(3):305-14. Epub 2007 Jan 30.


Associations between arsenic species in exfoliated urothelial cells and prevalence of diabetes among residents of Chihuahua, Mexico.

Currier JM, Ishida MC, González-Horta C, Sánchez-Ramírez B, Ballinas-Casarrubias L, Gutiérrez-Torres DS, Cerón RH, Morales DV, Terrazas FA, Del Razo LM, García-Vargas GG, Saunders RJ, Drobná Z, Fry RC, Matoušek T, Buse JB, Mendez MA, Loomis D, Stýblo M.

Environ Health Perspect. 2014 Oct;122(10):1088-94. doi: 10.1289/ehp.1307756. Epub 2014 Jun 27.


DNA methylation of extracellular matrix remodeling genes in children exposed to arsenic.

Gonzalez-Cortes T, Recio-Vega R, Lantz RC, Chau BT.

Toxicol Appl Pharmacol. 2017 Aug 15;329:140-147. doi: 10.1016/j.taap.2017.06.001. Epub 2017 Jun 1.


DNA hypermethylation of promoter of gene p53 and p16 in arsenic-exposed people with and without malignancy.

Chanda S, Dasgupta UB, Guhamazumder D, Gupta M, Chaudhuri U, Lahiri S, Das S, Ghosh N, Chatterjee D.

Toxicol Sci. 2006 Feb;89(2):431-7. Epub 2005 Oct 26.


Benchmark Dose Modeling Estimates of the Concentrations of Inorganic Arsenic That Induce Changes to the Neonatal Transcriptome, Proteome, and Epigenome in a Pregnancy Cohort.

Rager JE, Auerbach SS, Chappell GA, Martin E, Thompson CM, Fry RC.

Chem Res Toxicol. 2017 Oct 16;30(10):1911-1920. doi: 10.1021/acs.chemrestox.7b00221. Epub 2017 Sep 27.


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