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Items: 1 to 20 of 109

1.

Dnmt3b is a haploinsufficient tumor suppressor gene in Myc-induced lymphomagenesis.

Vasanthakumar A, Lepore JB, Zegarek MH, Kocherginsky M, Singh M, Davis EM, Link PA, Anastasi J, Le Beau MM, Karpf AR, Godley LA.

Blood. 2013 Mar 14;121(11):2059-63. doi: 10.1182/blood-2012-04-421065. Epub 2013 Jan 11.

2.

DNMT3B7, a truncated DNMT3B isoform expressed in human tumors, disrupts embryonic development and accelerates lymphomagenesis.

Shah MY, Vasanthakumar A, Barnes NY, Figueroa ME, Kamp A, Hendrick C, Ostler KR, Davis EM, Lin S, Anastasi J, Le Beau MM, Moskowitz IP, Melnick A, Pytel P, Godley LA.

Cancer Res. 2010 Jul 15;70(14):5840-50. doi: 10.1158/0008-5472.CAN-10-0847. Epub 2010 Jun 29.

3.

Methylation-independent repression of Dnmt3b contributes to oncogenic activity of Dnmt3a in mouse MYC-induced T-cell lymphomagenesis.

Haney SL, Hlady RA, Opavska J, Klinkebiel D, Pirruccello SJ, Dutta S, Datta K, Simpson MA, Wu L, Opavsky R.

Oncogene. 2015 Oct;34(43):5436-5446. doi: 10.1038/onc.2014.472. Epub 2015 Feb 2.

4.

A transgenic mouse model demonstrating the oncogenic role of mutations in the polycomb-group gene EZH2 in lymphomagenesis.

Berg T, Thoene S, Yap D, Wee T, Schoeler N, Rosten P, Lim E, Bilenky M, Mungall AJ, Oellerich T, Lee S, Lai CK, Umlandt P, Salmi A, Chang H, Yue L, Lai D, Cheng SW, Morin RD, Hirst M, Serve H, Marra MA, Morin GB, Gascoyne RD, Aparicio SA, Humphries RK.

Blood. 2014 Jun 19;123(25):3914-24. doi: 10.1182/blood-2012-12-473439. Epub 2014 May 6.

5.

Loss of Dnmt3b function upregulates the tumor modifier Ment and accelerates mouse lymphomagenesis.

Hlady RA, Novakova S, Opavska J, Klinkebiel D, Peters SL, Bies J, Hannah J, Iqbal J, Anderson KM, Siebler HM, Smith LM, Greiner TC, Bastola D, Joshi S, Lockridge O, Simpson MA, Felsher DW, Wagner KU, Chan WC, Christman JK, Opavsky R.

J Clin Invest. 2012 Jan;122(1):163-77. doi: 10.1172/JCI57292. Epub 2011 Dec 1.

6.

Cancer cells express aberrant DNMT3B transcripts encoding truncated proteins.

Ostler KR, Davis EM, Payne SL, Gosalia BB, Expósito-Céspedes J, Le Beau MM, Godley LA.

Oncogene. 2007 Aug 16;26(38):5553-63. Epub 2007 Mar 12.

7.

Essential role for Dnmt1 in the prevention and maintenance of MYC-induced T-cell lymphomas.

Peters SL, Hlady RA, Opavska J, Klinkebiel D, Novakova S, Smith LM, Lewis RE, Karpf AR, Simpson MA, Wu L, Opavsky R.

Mol Cell Biol. 2013 Nov;33(21):4321-33. doi: 10.1128/MCB.00776-13. Epub 2013 Sep 3.

8.

Truncated DNMT3B isoform DNMT3B7 suppresses growth, induces differentiation, and alters DNA methylation in human neuroblastoma.

Ostler KR, Yang Q, Looney TJ, Zhang L, Vasanthakumar A, Tian Y, Kocherginsky M, Raimondi SL, DeMaio JG, Salwen HR, Gu S, Chlenski A, Naranjo A, Gill A, Peddinti R, Lahn BT, Cohn SL, Godley LA.

Cancer Res. 2012 Sep 15;72(18):4714-23. doi: 10.1158/0008-5472.CAN-12-0886. Epub 2012 Jul 18.

9.

∆ DNMT3B4-del Contributes to Aberrant DNA Methylation Patterns in Lung Tumorigenesis.

Ma MZ, Lin R, Carrillo J, Bhutani M, Pathak A, Ren H, Li Y, Song J, Mao L.

EBioMedicine. 2015 Sep 7;2(10):1340-50. doi: 10.1016/j.ebiom.2015.09.002. eCollection 2015 Oct.

10.

Dnmt3/transcription factor interactions as crucial players in targeted DNA methylation.

Hervouet E, Vallette FM, Cartron PF.

Epigenetics. 2009 Oct 1;4(7):487-99. Epub 2009 Oct 21.

PMID:
19786833
11.
12.

DNMT3B7 expression related to MENT expression and its promoter methylation in human lymphomas.

Alkebsi L, Handa H, Sasaki Y, Osaki Y, Yanagisawa K, Ogawa Y, Yokohama A, Hattori H, Koiso H, Saitoh T, Mitsui T, Tsukamoto N, Nojima Y, Murakami H.

Leuk Res. 2013 Dec;37(12):1662-7. doi: 10.1016/j.leukres.2013.09.014. Epub 2013 Sep 21.

PMID:
24094886
13.

DNMT3b overexpression contributes to a hypermethylator phenotype in human breast cancer cell lines.

Roll JD, Rivenbark AG, Jones WD, Coleman WB.

Mol Cancer. 2008 Jan 25;7:15. doi: 10.1186/1476-4598-7-15.

14.

Histone H2AX suppresses translocations in lymphomas of Eμ-c-Myc transgenic mice that contain a germline amplicon of tumor-promoting genes.

Fusello A, Horowitz J, Yang-Iott K, Brady BL, Yin B, Rowh MA, Rappaport E, Bassing CH.

Cell Cycle. 2013 Sep 1;12(17):2867-75. doi: 10.4161/cc.25922. Epub 2013 Aug 8.

16.

MicroRNA biogenesis is required for Myc-induced B-cell lymphoma development and survival.

Arrate MP, Vincent T, Odvody J, Kar R, Jones SN, Eischen CM.

Cancer Res. 2010 Jul 15;70(14):6083-92. doi: 10.1158/0008-5472.CAN-09-4736. Epub 2010 Jun 29.

17.

Bim is a suppressor of Myc-induced mouse B cell leukemia.

Egle A, Harris AW, Bouillet P, Cory S.

Proc Natl Acad Sci U S A. 2004 Apr 20;101(16):6164-9. Epub 2004 Apr 12.

18.

Myc suppression of Nfkb2 accelerates lymphomagenesis.

Keller U, Huber J, Nilsson JA, Fallahi M, Hall MA, Peschel C, Cleveland JL.

BMC Cancer. 2010 Jul 2;10:348. doi: 10.1186/1471-2407-10-348.

19.

Dosage-dependent tumor suppression by histone deacetylases 1 and 2 through regulation of c-Myc collaborating genes and p53 function.

Heideman MR, Wilting RH, Yanover E, Velds A, de Jong J, Kerkhoven RM, Jacobs H, Wessels LF, Dannenberg JH.

Blood. 2013 Mar 14;121(11):2038-50. doi: 10.1182/blood-2012-08-450916. Epub 2013 Jan 17.

20.

DNA methyltransferase 3b contributes to oncogenic transformation induced by SV40T antigen and activated Ras.

Soejima K, Fang W, Rollins BJ.

Oncogene. 2003 Jul 24;22(30):4723-33.

PMID:
12879017

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