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Items: 1 to 20 of 121

1.

Brief maternal exposure of rats to the xenobiotics dibutyl phthalate or diethylstilbestrol alters adult-type Leydig cell development in male offspring.

Ivell R, Heng K, Nicholson H, Anand-Ivell R.

Asian J Androl. 2013 Mar;15(2):261-8. doi: 10.1038/aja.2012.138. Epub 2013 Jan 14.

2.

The endocrine disruptors dibutyl phthalate (DBP) and diethylstilbestrol (DES) influence Leydig cell regeneration following ethane dimethane sulphonate treatment of adult male rats.

Heng K, Anand-Ivell R, Teerds K, Ivell R.

Int J Androl. 2012 Jun;35(3):353-63. doi: 10.1111/j.1365-2605.2011.01231.x. Epub 2011 Dec 13.

PMID:
22150342
3.

Fetal testosterone insufficiency and abnormal proliferation of Leydig cells and gonocytes in rats exposed to di(n-butyl) phthalate.

Mylchreest E, Sar M, Wallace DG, Foster PM.

Reprod Toxicol. 2002 Jan-Feb;16(1):19-28.

PMID:
11934529
4.

Cumulative effects of dibutyl phthalate and diethylhexyl phthalate on male rat reproductive tract development: altered fetal steroid hormones and genes.

Howdeshell KL, Furr J, Lambright CR, Rider CV, Wilson VS, Gray LE Jr.

Toxicol Sci. 2007 Sep;99(1):190-202. Epub 2007 Mar 30.

PMID:
17400582
5.

The effects on steroidogenesis and histopathology of adult male Japanese quails (Coturnix coturnix japonica) testis following pre-pubertal exposure to di(n-butyl) phthalate (DBP).

Bello UM, Madekurozwa MC, Groenewald HB, Aire TA, Arukwe A.

Comp Biochem Physiol C Toxicol Pharmacol. 2014 Nov;166:24-33. doi: 10.1016/j.cbpc.2014.06.005. Epub 2014 Jun 28.

PMID:
24983780
6.

Quantitative changes in gene expression in fetal rat testes following exposure to di(n-butyl) phthalate.

Barlow NJ, Phillips SL, Wallace DG, Sar M, Gaido KW, Foster PM.

Toxicol Sci. 2003 Jun;73(2):431-41. Epub 2003 Apr 15.

PMID:
12700402
7.

Induction of spermatogenic cell apoptosis in prepubertal rat testes irrespective of testicular steroidogenesis: a possible estrogenic effect of di(n-butyl) phthalate.

Alam MS, Ohsako S, Matsuwaki T, Zhu XB, Tsunekawa N, Kanai Y, Sone H, Tohyama C, Kurohmaru M.

Reproduction. 2010 Feb;139(2):427-37. doi: 10.1530/REP-09-0226. Epub 2009 Nov 10.

8.

Male Sprague-Dawley rats exposed to in utero di(n-butyl) phthalate: dose dependent and age-related morphological changes in Leydig cell smooth endoplasmic reticulum.

Shirai M, Wakui S, Wempe MF, Mutou T, Oyama N, Motohashi M, Takahashi H, Kansaku N, Asari M, Hano H, Endou H.

Toxicol Pathol. 2013;41(7):984-91. doi: 10.1177/0192623312474725. Epub 2013 Feb 15.

PMID:
23416961
10.

Species-specific dibutyl phthalate fetal testis endocrine disruption correlates with inhibition of SREBP2-dependent gene expression pathways.

Johnson KJ, McDowell EN, Viereck MP, Xia JQ.

Toxicol Sci. 2011 Apr;120(2):460-74. doi: 10.1093/toxsci/kfr020. Epub 2011 Jan 25.

11.

Human 'testicular dysgenesis syndrome': a possible model using in-utero exposure of the rat to dibutyl phthalate.

Fisher JS, Macpherson S, Marchetti N, Sharpe RM.

Hum Reprod. 2003 Jul;18(7):1383-94.

PMID:
12832361
12.

Disruption of rat testis development following combined in utero exposure to the phytoestrogen genistein and antiandrogenic plasticizer di-(2-ethylhexyl) phthalate.

Jones S, Boisvert A, Duong TB, Francois S, Thrane P, Culty M.

Biol Reprod. 2014 Sep;91(3):64. doi: 10.1095/biolreprod.114.120907. Epub 2014 Jul 16.

PMID:
25031359
13.

In utero exposure to di-(2-ethylhexyl) phthalate exerts both short-term and long-lasting suppressive effects on testosterone production in the rat.

Culty M, Thuillier R, Li W, Wang Y, Martinez-Arguelles DB, Benjamin CG, Triantafilou KM, Zirkin BR, Papadopoulos V.

Biol Reprod. 2008 Jun;78(6):1018-28. doi: 10.1095/biolreprod.107.065649. Epub 2008 Mar 5.

PMID:
18322279
14.

In utero exposure to di-(2-ethylhexyl) phthalate induces testicular effects in neonatal rats that are antagonized by genistein cotreatment.

Jones S, Boisvert A, Francois S, Zhang L, Culty M.

Biol Reprod. 2015 Oct;93(4):92. doi: 10.1095/biolreprod.115.129098. Epub 2015 Aug 26.

15.

Expression of insulin-like factor 3 protein in the rat testis during fetal and postnatal development and in relation to cryptorchidism induced by in utero exposure to di (n-Butyl) phthalate.

McKinnell C, Sharpe RM, Mahood K, Hallmark N, Scott H, Ivell R, Staub C, J├ęgou B, Haag F, Koch-Nolte F, Hartung S.

Endocrinology. 2005 Oct;146(10):4536-44. Epub 2005 Jul 21.

PMID:
16037377
16.

Reproductive toxicity and pharmacokinetics of di-n-butyl phthalate (DBP) following dietary exposure of pregnant rats.

Struve MF, Gaido KW, Hensley JB, Lehmann KP, Ross SM, Sochaski MA, Willson GA, Dorman DC.

Birth Defects Res B Dev Reprod Toxicol. 2009 Aug;86(4):345-54. doi: 10.1002/bdrb.20199.

PMID:
19585553
17.

Dipentyl phthalate dosing during sexual differentiation disrupts fetal testis function and postnatal development of the male Sprague-Dawley rat with greater relative potency than other phthalates.

Hannas BR, Furr J, Lambright CS, Wilson VS, Foster PM, Gray LE Jr.

Toxicol Sci. 2011 Mar;120(1):184-93. doi: 10.1093/toxsci/kfq386. Epub 2010 Dec 20.

18.

In utero exposure to di(n-butyl) phthalate and testicular dysgenesis: comparison of fetal and adult end points and their dose sensitivity.

Mahood IK, Scott HM, Brown R, Hallmark N, Walker M, Sharpe RM.

Environ Health Perspect. 2007 Dec;115 Suppl 1:55-61. doi: 10.1289/ehp.9366.

19.

Abnormal Leydig Cell aggregation in the fetal testis of rats exposed to di (n-butyl) phthalate and its possible role in testicular dysgenesis.

Mahood IK, Hallmark N, McKinnell C, Walker M, Fisher JS, Sharpe RM.

Endocrinology. 2005 Feb;146(2):613-23. Epub 2004 Nov 11.

PMID:
15539561
20.

Altered gene profiles in fetal rat testes after in utero exposure to di(n-butyl) phthalate.

Shultz VD, Phillips S, Sar M, Foster PM, Gaido KW.

Toxicol Sci. 2001 Dec;64(2):233-42.

PMID:
11719706

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