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Adenosine nucleotide biosynthesis and AMPK regulate adult life span and mediate the longevity benefit of caloric restriction in flies.

Stenesen D, Suh JM, Seo J, Yu K, Lee KS, Kim JS, Min KJ, Graff JM.

Cell Metab. 2013 Jan 8;17(1):101-12. doi: 10.1016/j.cmet.2012.12.006.


Sensing of energy and nutrients by AMP-activated protein kinase.

Hardie DG.

Am J Clin Nutr. 2011 Apr;93(4):891S-6. doi: 10.3945/ajcn.110.001925. Epub 2011 Feb 16. Review.


Calorie restriction: is AMPK a key sensor and effector?

Cantó C, Auwerx J.

Physiology (Bethesda). 2011 Aug;26(4):214-24. doi: 10.1152/physiol.00010.2011. Review.


AMPK is a direct adenylate charge-regulated protein kinase.

Oakhill JS, Steel R, Chen ZP, Scott JW, Ling N, Tam S, Kemp BE.

Science. 2011 Jun 17;332(6036):1433-5. doi: 10.1126/science.1200094.


AMP-activated protein kinase: a cellular energy sensor with a key role in metabolic disorders and in cancer.

Hardie DG.

Biochem Soc Trans. 2011 Jan;39(1):1-13. doi: 10.1042/BST0390001.


Effect of dietary macronutrient composition on AMPK and SIRT1 expression and activity in human skeletal muscle.

Draznin B, Wang C, Adochio R, Leitner JW, Cornier MA.

Horm Metab Res. 2012 Sep;44(9):650-5. doi: 10.1055/s-0032-1312656. Epub 2012 Jun 6.


AMP-activated protein kinase in metabolic control and insulin signaling.

Towler MC, Hardie DG.

Circ Res. 2007 Feb 16;100(3):328-41. Review.


Iron regulates glucose homeostasis in liver and muscle via AMP-activated protein kinase in mice.

Huang J, Simcox J, Mitchell TC, Jones D, Cox J, Luo B, Cooksey RC, Boros LG, McClain DA.

FASEB J. 2013 Jul;27(7):2845-54. doi: 10.1096/fj.12-216929. Epub 2013 Mar 20.


A critical role of SNF1A/dAMPKalpha (Drosophila AMP-activated protein kinase alpha) in muscle on longevity and stress resistance in Drosophila melanogaster.

Tohyama D, Yamaguchi A.

Biochem Biophys Res Commun. 2010 Mar 26;394(1):112-8. doi: 10.1016/j.bbrc.2010.02.126. Epub 2010 Feb 23.


AMP-activated protein kinase--a sensor of glycogen as well as AMP and ATP?

McBride A, Hardie DG.

Acta Physiol (Oxf). 2009 May;196(1):99-113. doi: 10.1111/j.1748-1716.2009.01975.x. Epub 2009 Feb 19. Review.


Energy sensing by the AMP-activated protein kinase and its effects on muscle metabolism.

Hardie DG.

Proc Nutr Soc. 2011 Feb;70(1):92-9. doi: 10.1017/S0029665110003915. Epub 2010 Nov 11. Review.


AMP as a low-energy charge signal autonomously initiates assembly of AXIN-AMPK-LKB1 complex for AMPK activation.

Zhang YL, Guo H, Zhang CS, Lin SY, Yin Z, Peng Y, Luo H, Shi Y, Lian G, Zhang C, Li M, Ye Z, Ye J, Han J, Li P, Wu JW, Lin SC.

Cell Metab. 2013 Oct 1;18(4):546-55. doi: 10.1016/j.cmet.2013.09.005.


AMPK activation regulates neuronal structure in developing hippocampal neurons.

Ramamurthy S, Chang E, Cao Y, Zhu J, Ronnett GV.

Neuroscience. 2014 Feb 14;259:13-24. doi: 10.1016/j.neuroscience.2013.11.048. Epub 2013 Dec 1.


AMPK directly inhibits NDPK through a phosphoserine switch to maintain cellular homeostasis.

Onyenwoke RU, Forsberg LJ, Liu L, Williams T, Alzate O, Brenman JE.

Mol Biol Cell. 2012 Jan;23(2):381-9. doi: 10.1091/mbc.E11-08-0699. Epub 2011 Nov 23.


[Regulation of energy metabolism by AMPK: a novel therapeutic approach for the treatment of metabolic and cardiovascular diseases].

Foretz M, Taleux N, Guigas B, Horman S, Beauloye C, Andreelli F, Bertrand L, Viollet B.

Med Sci (Paris). 2006 Apr;22(4):381-8. Review. French.


N488I mutation of the gamma2-subunit results in bidirectional changes in AMP-activated protein kinase activity.

Zou L, Shen M, Arad M, He H, Løfgren B, Ingwall JS, Seidman CE, Seidman JG, Tian R.

Circ Res. 2005 Aug 19;97(4):323-8. Epub 2005 Jul 28.


Activation of AMPK by the putative dietary restriction mimetic metformin is insufficient to extend lifespan in Drosophila.

Slack C, Foley A, Partridge L.

PLoS One. 2012;7(10):e47699. doi: 10.1371/journal.pone.0047699. Epub 2012 Oct 16.


Effects of pharmacological AMP deaminase inhibition and Ampd1 deletion on nucleotide levels and AMPK activation in contracting skeletal muscle.

Plaideau C, Lai YC, Kviklyte S, Zanou N, Löfgren L, Andersén H, Vertommen D, Gailly P, Hue L, Bohlooly-Y M, Hallén S, Rider MH.

Chem Biol. 2014 Nov 20;21(11):1497-1510. doi: 10.1016/j.chembiol.2014.09.013.


Thyroid hormone activates rat liver adenosine 5,-monophosphate-activated protein kinase: relation to CaMKKb, TAK1 and LKB1 expression and energy status.

Vargas R, Ortega Y, Bozo V, Andrade M, Minuzzi G, Cornejo P, Fernandez V, Videla LA.

J Biol Regul Homeost Agents. 2013 Oct-Dec;27(4):989-99.


Dissecting the role of 5'-AMP for allosteric stimulation, activation, and deactivation of AMP-activated protein kinase.

Suter M, Riek U, Tuerk R, Schlattner U, Wallimann T, Neumann D.

J Biol Chem. 2006 Oct 27;281(43):32207-16. Epub 2006 Aug 30.

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