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Items: 1 to 20 of 108

1.

Inhibition of a NEDD8 Cascade Restores Restriction of HIV by APOBEC3G.

Stanley DJ, Bartholomeeusen K, Crosby DC, Kim DY, Kwon E, Yen L, Cartozo NC, Li M, Jäger S, Mason-Herr J, Hayashi F, Yokoyama S, Krogan NJ, Harris RS, Peterlin BM, Gross JD.

PLoS Pathog. 2012 Dec;8(12):e1003085. doi: 10.1371/journal.ppat.1003085.

2.

Vif hijacks CBF-β to degrade APOBEC3G and promote HIV-1 infection.

Jäger S, Kim DY, Hultquist JF, Shindo K, LaRue RS, Kwon E, Li M, Anderson BD, Yen L, Stanley D, Mahon C, Kane J, Franks-Skiba K, Cimermancic P, Burlingame A, Sali A, Craik CS, Harris RS, Gross JD, Krogan NJ.

Nature. 2011 Dec 21;481(7381):371-5. doi: 10.1038/nature10693.

3.

T-cell differentiation factor CBF-β regulates HIV-1 Vif-mediated evasion of host restriction.

Zhang W, Du J, Evans SL, Yu Y, Yu XF.

Nature. 2011 Dec 21;481(7381):376-9. doi: 10.1038/nature10718.

PMID:
22190036
4.

Identification of an HIV-1 replication inhibitor which rescues host restriction factor APOBEC3G in Vif-APOBEC3G complex.

Zhang S, Zhong L, Chen B, Pan T, Zhang X, Liang L, Li Q, Zhang Z, Chen H, Zhou J, Luo H, Zhang H, Bai C.

Antiviral Res. 2015 Oct;122:20-7. doi: 10.1016/j.antiviral.2015.07.009.

PMID:
26241003
5.

APOBEC3G is degraded by the proteasomal pathway in a Vif-dependent manner without being polyubiquitylated.

Dang Y, Siew LM, Zheng YH.

J Biol Chem. 2008 May 9;283(19):13124-31. doi: 10.1074/jbc.M708728200.

6.

ASK1 restores the antiviral activity of APOBEC3G by disrupting HIV-1 Vif-mediated counteraction.

Miyakawa K, Matsunaga S, Kanou K, Matsuzawa A, Morishita R, Kudoh A, Shindo K, Yokoyama M, Sato H, Kimura H, Tamura T, Yamamoto N, Ichijo H, Takaori-Kondo A, Ryo A.

Nat Commun. 2015 Apr 22;6:6945. doi: 10.1038/ncomms7945.

7.

Biochemical and cellular effects of inhibiting Nedd8 conjugation.

Leck YC, Choo YY, Tan CY, Smith PG, Hagen T.

Biochem Biophys Res Commun. 2010 Jul 30;398(3):588-93. doi: 10.1016/j.bbrc.2010.06.128.

PMID:
20603103
8.

The HIV-1 Vif PPLP motif is necessary for human APOBEC3G binding and degradation.

Donahue JP, Vetter ML, Mukhtar NA, D'Aquila RT.

Virology. 2008 Jul 20;377(1):49-53. doi: 10.1016/j.virol.2008.04.017.

9.

Core binding factor beta plays a critical role by facilitating the assembly of the Vif-cullin 5 E3 ubiquitin ligase.

Fribourgh JL, Nguyen HC, Wolfe LS, Dewitt DC, Zhang W, Yu XF, Rhoades E, Xiong Y.

J Virol. 2014 Mar;88(6):3309-19. doi: 10.1128/JVI.03824-13.

10.

HIV-1 Vif-mediated ubiquitination/degradation of APOBEC3G involves four critical lysine residues in its C-terminal domain.

Iwatani Y, Chan DS, Liu L, Yoshii H, Shibata J, Yamamoto N, Levin JG, Gronenborn AM, Sugiura W.

Proc Natl Acad Sci U S A. 2009 Nov 17;106(46):19539-44. doi: 10.1073/pnas.0906652106.

11.

Characterization of MRFAP1 turnover and interactions downstream of the NEDD8 pathway.

Larance M, Kirkwood KJ, Xirodimas DP, Lundberg E, Uhlen M, Lamond AI.

Mol Cell Proteomics. 2012 Mar;11(3):M111.014407. doi: 10.1074/mcp.M111.014407.

12.

HIV relies on neddylation for ubiquitin ligase-mediated functions.

Nekorchuk MD, Sharifi HJ, Furuya AK, Jellinger R, de Noronha CM.

Retrovirology. 2013 Nov 18;10:138. doi: 10.1186/1742-4690-10-138.

13.

MDM2 is a novel E3 ligase for HIV-1 Vif.

Izumi T, Takaori-Kondo A, Shirakawa K, Higashitsuji H, Itoh K, Io K, Matsui M, Iwai K, Kondoh H, Sato T, Tomonaga M, Ikeda S, Akari H, Koyanagi Y, Fujita J, Uchiyama T.

Retrovirology. 2009 Jan 7;6:1. doi: 10.1186/1742-4690-6-1.

14.

Evolutionarily conserved requirement for core binding factor beta in the assembly of the human immunodeficiency virus/simian immunodeficiency virus Vif-cullin 5-RING E3 ubiquitin ligase.

Han X, Liang W, Hua D, Zhou X, Du J, Evans SL, Gao Q, Wang H, Viqueira R, Wei W, Zhang W, Yu XF.

J Virol. 2014 Mar;88(6):3320-8. doi: 10.1128/JVI.03833-13.

15.

Cellular requirements for bovine immunodeficiency virus Vif-mediated inactivation of bovine APOBEC3 proteins.

Zhang W, Wang H, Li Z, Liu X, Liu G, Harris RS, Yu XF.

J Virol. 2014 Nov;88(21):12528-40. doi: 10.1128/JVI.02072-14.

16.

E2-RING expansion of the NEDD8 cascade confers specificity to cullin modification.

Huang DT, Ayrault O, Hunt HW, Taherbhoy AM, Duda DM, Scott DC, Borg LA, Neale G, Murray PJ, Roussel MF, Schulman BA.

Mol Cell. 2009 Feb 27;33(4):483-95. doi: 10.1016/j.molcel.2009.01.011.

17.

Endogenous origins of HIV-1 G-to-A hypermutation and restriction in the nonpermissive T cell line CEM2n.

Refsland EW, Hultquist JF, Harris RS.

PLoS Pathog. 2012;8(7):e1002800. doi: 10.1371/journal.ppat.1002800.

18.

Induction of APOBEC3G ubiquitination and degradation by an HIV-1 Vif-Cul5-SCF complex.

Yu X, Yu Y, Liu B, Luo K, Kong W, Mao P, Yu XF.

Science. 2003 Nov 7;302(5647):1056-60.

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