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Items: 1 to 20 of 92

1.

Differential processing of amyloid precursor protein in brain and in peripheral blood leukocytes.

Delvaux E, Bentley K, Stubbs V, Sabbagh M, Coleman PD.

Neurobiol Aging. 2013 Jun;34(6):1680-6. doi: 10.1016/j.neurobiolaging.2012.12.004. Epub 2013 Jan 5.

2.

Platelet amyloid precursor protein processing: a bio-marker for Alzheimer's disease.

Tang K, Hynan LS, Baskin F, Rosenberg RN.

J Neurol Sci. 2006 Jan 15;240(1-2):53-8. Epub 2005 Oct 26.

3.

Mitochondria-targeted catalase reduces abnormal APP processing, amyloid β production and BACE1 in a mouse model of Alzheimer's disease: implications for neuroprotection and lifespan extension.

Mao P, Manczak M, Calkins MJ, Truong Q, Reddy TP, Reddy AP, Shirendeb U, Lo HH, Rabinovitch PS, Reddy PH.

Hum Mol Genet. 2012 Jul 1;21(13):2973-90. doi: 10.1093/hmg/dds128. Epub 2012 Apr 5.

4.

Proteolytic processing of the Alzheimer's disease amyloid precursor protein in brain and platelets.

Evin G, Zhu A, Holsinger RM, Masters CL, Li QX.

J Neurosci Res. 2003 Nov 1;74(3):386-92.

PMID:
14598315
5.

Excess of nicastrin in brain results in heterozygosity having no effect on endogenous APP processing and amyloid peptide levels in vivo.

Brijbassi S, Amtul Z, Newbigging S, Westaway D, St George-Hyslop P, Rozmahel RF.

Neurobiol Dis. 2007 Feb;25(2):291-6. Epub 2006 Oct 27.

PMID:
17071095
7.

Phosphorylation of amyloid precursor carboxy-terminal fragments enhances their processing by a gamma-secretase-dependent mechanism.

Vingtdeux V, Hamdane M, Gompel M, Bégard S, Drobecq H, Ghestem A, Grosjean ME, Kostanjevecki V, Grognet P, Vanmechelen E, Buée L, Delacourte A, Sergeant N.

Neurobiol Dis. 2005 Nov;20(2):625-37. Epub 2005 Jun 3.

PMID:
15936948
8.

Cerebrolysin decreases amyloid-beta production by regulating amyloid protein precursor maturation in a transgenic model of Alzheimer's disease.

Rockenstein E, Torrance M, Mante M, Adame A, Paulino A, Rose JB, Crews L, Moessler H, Masliah E.

J Neurosci Res. 2006 May 15;83(7):1252-61.

PMID:
16511867
9.

Processing of beta-amyloid precursor-like protein-1 and -2 by gamma-secretase regulates transcription.

Scheinfeld MH, Ghersi E, Laky K, Fowlkes BJ, D'Adamio L.

J Biol Chem. 2002 Nov 15;277(46):44195-201. Epub 2002 Sep 12.

10.

The amyloid precursor protein of Alzheimer disease in human brain and blood.

Li QX, Fuller SJ, Beyreuther K, Masters CL.

J Leukoc Biol. 1999 Oct;66(4):567-74. Review.

PMID:
10534110
11.

Activation of peroxisome proliferator-activated receptor α stimulates ADAM10-mediated proteolysis of APP.

Corbett GT, Gonzalez FJ, Pahan K.

Proc Natl Acad Sci U S A. 2015 Jul 7;112(27):8445-50. doi: 10.1073/pnas.1504890112. Epub 2015 Jun 15.

12.

A strategy focused on MAPT, APP, NCSTN and BACE1 to build blood classifiers for Alzheimer's disease.

Herrera-Rivero M, Elena Hernández-Aguilar M, Emiliano Aranda-Abreu G.

J Theor Biol. 2015 Jul 7;376:32-8. doi: 10.1016/j.jtbi.2015.03.039. Epub 2015 Apr 8.

PMID:
25863267
13.

Relationship between ubiquilin-1 and BACE1 in human Alzheimer's disease and APdE9 transgenic mouse brain and cell-based models.

Natunen T, Takalo M, Kemppainen S, Leskelä S, Marttinen M, Kurkinen KMA, Pursiheimo JP, Sarajärvi T, Viswanathan J, Gabbouj S, Solje E, Tahvanainen E, Pirttimäki T, Kurki M, Paananen J, Rauramaa T, Miettinen P, Mäkinen P, Leinonen V, Soininen H, Airenne K, Tanzi RE, Tanila H, Haapasalo A, Hiltunen M.

Neurobiol Dis. 2016 Jan;85:187-205. doi: 10.1016/j.nbd.2015.11.005. Epub 2015 Nov 10.

PMID:
26563932
15.

Beta-amyloid secretases and beta-amloid degrading enzyme expression in lens.

Li G, Percontino L, Sun Q, Qazi AS, Frederikse PH.

Mol Vis. 2003 May 1;9:179-83.

16.

In vivo beta-secretase 1 inhibition leads to brain Abeta lowering and increased alpha-secretase processing of amyloid precursor protein without effect on neuregulin-1.

Sankaranarayanan S, Price EA, Wu G, Crouthamel MC, Shi XP, Tugusheva K, Tyler KX, Kahana J, Ellis J, Jin L, Steele T, Stachel S, Coburn C, Simon AJ.

J Pharmacol Exp Ther. 2008 Mar;324(3):957-69. Epub 2007 Dec 21.

17.

Decrease in brain soluble amyloid precursor protein β (sAPPβ) in Alzheimer's disease cortex.

Wu G, Sankaranarayanan S, Hsieh SH, Simon AJ, Savage MJ.

J Neurosci Res. 2011 Jun;89(6):822-32. doi: 10.1002/jnr.22618. Epub 2011 Mar 23.

PMID:
21433051
18.

APP processing is regulated by cytoplasmic phosphorylation.

Lee MS, Kao SC, Lemere CA, Xia W, Tseng HC, Zhou Y, Neve R, Ahlijanian MK, Tsai LH.

J Cell Biol. 2003 Oct 13;163(1):83-95.

19.

[alpha]-Secretase ADAM10 as well as [alpha]APPs is reduced in platelets and CSF of Alzheimer disease patients.

Colciaghi F, Borroni B, Pastorino L, Marcello E, Zimmermann M, Cattabeni F, Padovani A, Di Luca M.

Mol Med. 2002 Feb;8(2):67-74.

20.

Alzheimer's disease: beta-amyloid precursor protein mRNA expression in mononuclear blood cells.

Allen JS, Murphy GM Jr, Eng LF, Stultz KE, Davies HD, Pickford LB, Tinklenberg JR.

Neurosci Lett. 1991 Oct 28;132(1):109-12.

PMID:
1838578

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