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Items: 1 to 20 of 142

1.

Muscle-specific microRNA1 (miR1) targets heat shock protein 70 (HSP70) during dexamethasone-mediated atrophy.

Kukreti H, Amuthavalli K, Harikumar A, Sathiyamoorthy S, Feng PZ, Anantharaj R, Tan SL, Lokireddy S, Bonala S, Sriram S, McFarlane C, Kambadur R, Sharma M.

J Biol Chem. 2013 Mar 1;288(9):6663-78. doi: 10.1074/jbc.M112.390369. Epub 2013 Jan 6.

2.

Hsp70 overexpression inhibits NF-kappaB and Foxo3a transcriptional activities and prevents skeletal muscle atrophy.

Senf SM, Dodd SL, McClung JM, Judge AR.

FASEB J. 2008 Nov;22(11):3836-45. doi: 10.1096/fj.08-110163. Epub 2008 Jul 21.

PMID:
18644837
3.

The IGF-1/PI3K/Akt pathway prevents expression of muscle atrophy-induced ubiquitin ligases by inhibiting FOXO transcription factors.

Stitt TN, Drujan D, Clarke BA, Panaro F, Timofeyva Y, Kline WO, Gonzalez M, Yancopoulos GD, Glass DJ.

Mol Cell. 2004 May 7;14(3):395-403.

4.

Suppression of atrogin-1 and MuRF1 prevents dexamethasone-induced atrophy of cultured myotubes.

Castillero E, Alamdari N, Lecker SH, Hasselgren PO.

Metabolism. 2013 Oct;62(10):1495-502. doi: 10.1016/j.metabol.2013.05.018. Epub 2013 Jul 15.

PMID:
23866982
5.

Human skeletal muscle atrophy in amyotrophic lateral sclerosis reveals a reduction in Akt and an increase in atrogin-1.

Léger B, Vergani L, Sorarù G, Hespel P, Derave W, Gobelet C, D'Ascenzio C, Angelini C, Russell AP.

FASEB J. 2006 Mar;20(3):583-5. Epub 2006 Jan 17.

PMID:
16507768
6.

Muscle sparing in muscle RING finger 1 null mice: response to synthetic glucocorticoids.

Baehr LM, Furlow JD, Bodine SC.

J Physiol. 2011 Oct 1;589(Pt 19):4759-76. doi: 10.1113/jphysiol.2011.212845. Epub 2011 Aug 1.

7.

IGF-I stimulates muscle growth by suppressing protein breakdown and expression of atrophy-related ubiquitin ligases, atrogin-1 and MuRF1.

Sacheck JM, Ohtsuka A, McLary SC, Goldberg AL.

Am J Physiol Endocrinol Metab. 2004 Oct;287(4):E591-601. Epub 2004 Apr 20.

PMID:
15100091
8.

Iron-induced skeletal muscle atrophy involves an Akt-forkhead box O3-E3 ubiquitin ligase-dependent pathway.

Ikeda Y, Imao M, Satoh A, Watanabe H, Hamano H, Horinouchi Y, Izawa-Ishizawa Y, Kihira Y, Miyamoto L, Ishizawa K, Tsuchiya K, Tamaki T.

J Trace Elem Med Biol. 2016 May;35:66-76. doi: 10.1016/j.jtemb.2016.01.011. Epub 2016 Jan 28.

PMID:
27049128
9.

mTORC1 promotes denervation-induced muscle atrophy through a mechanism involving the activation of FoxO and E3 ubiquitin ligases.

Tang H, Inoki K, Lee M, Wright E, Khuong A, Khuong A, Sugiarto S, Garner M, Paik J, DePinho RA, Goldman D, Guan KL, Shrager JB.

Sci Signal. 2014 Feb 25;7(314):ra18. doi: 10.1126/scisignal.2004809.

PMID:
24570486
10.

Celastrol overcomes HSP72 gene silencing-mediated muscle atrophy and induces myofiber preservation.

Gwag T, Park K, Park J, Lee JH, Nikawa T, Choi I.

J Physiol Pharmacol. 2015 Apr;66(2):273-83.

11.

Mechanisms involved in 3',5'-cyclic adenosine monophosphate-mediated inhibition of the ubiquitin-proteasome system in skeletal muscle.

Gonçalves DA, Lira EC, Baviera AM, Cao P, Zanon NM, Arany Z, Bedard N, Tanksale P, Wing SS, Lecker SH, Kettelhut IC, Navegantes LC.

Endocrinology. 2009 Dec;150(12):5395-404. doi: 10.1210/en.2009-0428. Epub 2009 Oct 16.

PMID:
19837877
12.

Sepsis increases the expression and activity of the transcription factor Forkhead Box O 1 (FOXO1) in skeletal muscle by a glucocorticoid-dependent mechanism.

Smith IJ, Alamdari N, O'Neal P, Gonnella P, Aversa Z, Hasselgren PO.

Int J Biochem Cell Biol. 2010 May;42(5):701-11. doi: 10.1016/j.biocel.2010.01.006. Epub 2010 Jan 13.

13.

A cell-autonomous role for the glucocorticoid receptor in skeletal muscle atrophy induced by systemic glucocorticoid exposure.

Watson ML, Baehr LM, Reichardt HM, Tuckermann JP, Bodine SC, Furlow JD.

Am J Physiol Endocrinol Metab. 2012 May 1;302(10):E1210-20. doi: 10.1152/ajpendo.00512.2011. Epub 2012 Feb 21.

14.
15.

miR-182 attenuates atrophy-related gene expression by targeting FoxO3 in skeletal muscle.

Hudson MB, Rahnert JA, Zheng B, Woodworth-Hobbs ME, Franch HA, Price SR.

Am J Physiol Cell Physiol. 2014 Aug 15;307(4):C314-9. doi: 10.1152/ajpcell.00395.2013. Epub 2014 May 28.

16.

Resveratrol prevents TNF-α-induced muscle atrophy via regulation of Akt/mTOR/FoxO1 signaling in C2C12 myotubes.

Wang DT, Yin Y, Yang YJ, Lv PJ, Shi Y, Lu L, Wei LB.

Int Immunopharmacol. 2014 Apr;19(2):206-13. doi: 10.1016/j.intimp.2014.02.002. Epub 2014 Feb 15.

PMID:
24534773
17.

Differential gene expression of muscle-specific ubiquitin ligase MAFbx/Atrogin-1 and MuRF1 in response to immobilization-induced atrophy of slow-twitch and fast-twitch muscles.

Okamoto T, Torii S, Machida S.

J Physiol Sci. 2011 Nov;61(6):537-46. doi: 10.1007/s12576-011-0175-6. Epub 2011 Sep 8.

PMID:
21901639
18.

The glucocorticoid receptor and FOXO1 synergistically activate the skeletal muscle atrophy-associated MuRF1 gene.

Waddell DS, Baehr LM, van den Brandt J, Johnsen SA, Reichardt HM, Furlow JD, Bodine SC.

Am J Physiol Endocrinol Metab. 2008 Oct;295(4):E785-97. doi: 10.1152/ajpendo.00646.2007. Epub 2008 Jul 8.

19.

Angiotensin-(1-7) decreases skeletal muscle atrophy induced by angiotensin II through a Mas receptor-dependent mechanism.

Cisternas F, Morales MG, Meneses C, Simon F, Brandan E, Abrigo J, Vazquez Y, Cabello-Verrugio C.

Clin Sci (Lond). 2015 Mar;128(5):307-19. doi: 10.1042/CS20140215.

PMID:
25222828
20.

SMAD3 augments FoxO3-induced MuRF-1 promoter activity in a DNA-binding-dependent manner.

Bollinger LM, Witczak CA, Houmard JA, Brault JJ.

Am J Physiol Cell Physiol. 2014 Aug 1;307(3):C278-87. doi: 10.1152/ajpcell.00391.2013. Epub 2014 Jun 11.

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