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Items: 1 to 20 of 83

1.

The ULK1 complex: sensing nutrient signals for autophagy activation.

Wong PM, Puente C, Ganley IG, Jiang X.

Autophagy. 2013 Feb 1;9(2):124-37. doi: 10.4161/auto.23323. Epub 2013 Jan 7. Review.

2.

AMPK and mTOR coordinate the regulation of Ulk1 and mammalian autophagy initiation.

Shang L, Wang X.

Autophagy. 2011 Aug;7(8):924-6. Epub 2011 Aug 1.

PMID:
21521945
3.

The autophagy initiating kinase ULK1 is regulated via opposing phosphorylation by AMPK and mTOR.

Egan D, Kim J, Shaw RJ, Guan KL.

Autophagy. 2011 Jun;7(6):643-4. Epub 2011 Jun 1.

4.

UNC51-like kinase 1, autophagic regulator and cancer therapeutic target.

Chen Y, He J, Tian M, Zhang SY, Guo MR, Kasimu R, Wang JH, Ouyang L.

Cell Prolif. 2014 Dec;47(6):494-505. doi: 10.1111/cpr.12145. Epub 2014 Oct 20. Review.

PMID:
25327638
5.

The role of the Atg1/ULK1 complex in autophagy regulation.

Mizushima N.

Curr Opin Cell Biol. 2010 Apr;22(2):132-9. doi: 10.1016/j.ceb.2009.12.004. Epub 2010 Jan 6. Review.

PMID:
20056399
6.

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1.

Kim J, Kundu M, Viollet B, Guan KL.

Nat Cell Biol. 2011 Feb;13(2):132-41. doi: 10.1038/ncb2152. Epub 2011 Jan 23.

7.

Regulation of nutrient-sensitive autophagy by uncoordinated 51-like kinases 1 and 2.

McAlpine F, Williamson LE, Tooze SA, Chan EY.

Autophagy. 2013 Mar;9(3):361-73. doi: 10.4161/auto.23066. Epub 2013 Jan 4.

8.

The association of AMPK with ULK1 regulates autophagy.

Lee JW, Park S, Takahashi Y, Wang HG.

PLoS One. 2010 Nov 3;5(11):e15394. doi: 10.1371/journal.pone.0015394.

9.

Regulation of the autophagy initiating kinase ULK1 by nutrients: roles of mTORC1 and AMPK.

Kim J, Guan KL.

Cell Cycle. 2011 May 1;10(9):1337-8. doi: 10.4161/cc.10.9.15291. Epub 2011 Mar 15.

PMID:
21403467
10.

Binding of the Atg1/ULK1 kinase to the ubiquitin-like protein Atg8 regulates autophagy.

Kraft C, Kijanska M, Kalie E, Siergiejuk E, Lee SS, Semplicio G, Stoffel I, Brezovich A, Verma M, Hansmann I, Ammerer G, Hofmann K, Tooze S, Peter M.

EMBO J. 2012 Sep 12;31(18):3691-703. doi: 10.1038/emboj.2012.225. Epub 2012 Aug 10.

11.

Unc-51 like kinase 1 (ULK1) in silico analysis for biomarker identification: a vital component of autophagy.

Randhawa R, Sehgal M, Singh TR, Duseja A, Changotra H.

Gene. 2015 May 10;562(1):40-9. doi: 10.1016/j.gene.2015.02.056. Epub 2015 Feb 19.

PMID:
25701603
12.

ATG13: just a companion, or an executor of the autophagic program?

Alers S, Wesselborg S, Stork B.

Autophagy. 2014 Jun;10(6):944-56. doi: 10.4161/auto.28987. Review. Erratum in: Autophagy. 2014 Aug;10(8):1481.

13.

Structure and function of the ULK1 complex in autophagy.

Lin MG, Hurley JH.

Curr Opin Cell Biol. 2016 Apr;39:61-8. doi: 10.1016/j.ceb.2016.02.010. Epub 2016 Feb 27. Review.

14.

ULK1.ATG13.FIP200 complex mediates mTOR signaling and is essential for autophagy.

Ganley IG, Lam du H, Wang J, Ding X, Chen S, Jiang X.

J Biol Chem. 2009 May 1;284(18):12297-305. doi: 10.1074/jbc.M900573200. Epub 2009 Mar 3.

15.

Nutrient starvation elicits an acute autophagic response mediated by Ulk1 dephosphorylation and its subsequent dissociation from AMPK.

Shang L, Chen S, Du F, Li S, Zhao L, Wang X.

Proc Natl Acad Sci U S A. 2011 Mar 22;108(12):4788-93. doi: 10.1073/pnas.1100844108. Epub 2011 Mar 7.

16.

Phosphorylation of ULK1 (hATG1) by AMP-activated protein kinase connects energy sensing to mitophagy.

Egan DF, Shackelford DB, Mihaylova MM, Gelino S, Kohnz RA, Mair W, Vasquez DS, Joshi A, Gwinn DM, Taylor R, Asara JM, Fitzpatrick J, Dillin A, Viollet B, Kundu M, Hansen M, Shaw RJ.

Science. 2011 Jan 28;331(6016):456-61. doi: 10.1126/science.1196371. Epub 2010 Dec 23.

17.

Role of an intrinsically disordered conformation in AMPK-mediated phosphorylation of ULK1 and regulation of autophagy.

Khan SH, Kumar R.

Mol Biosyst. 2012 Jan;8(1):91-6. doi: 10.1039/c1mb05265a. Epub 2011 Aug 18. Review.

PMID:
21853163
18.

Study of ULK1 Catalytic Activity and Its Regulation.

Stork B, Dengjel J.

Methods Enzymol. 2017;587:391-404. doi: 10.1016/bs.mie.2016.09.067. Epub 2016 Nov 18.

PMID:
28253968
19.

A novel, human Atg13 binding protein, Atg101, interacts with ULK1 and is essential for macroautophagy.

Mercer CA, Kaliappan A, Dennis PB.

Autophagy. 2009 Jul;5(5):649-62. Epub 2009 Jul 20.

PMID:
19287211
20.

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