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Items: 1 to 20 of 87

1.

A general approach for controlling transcription and probing epigenetic mechanisms: application to the CD4 locus.

Wan M, Kaundal R, Huang H, Zhao J, Yang X, Chaiyachati BH, Li S, Chi T.

J Immunol. 2013 Jan 15;190(2):737-47. doi: 10.4049/jimmunol.1201278.

2.

Nucleoprotein structure of the CD4 locus: implications for the mechanisms underlying CD4 regulation during T cell development.

Yu M, Wan M, Zhang J, Wu J, Khatri R, Chi T.

Proc Natl Acad Sci U S A. 2008 Mar 11;105(10):3873-8. doi: 10.1073/pnas.0800810105. Epub 2008 Mar 5. Erratum in: Proc Natl Acad Sci U S A. 2008 Apr 29;105(17):6502.

3.

Transcription factor AP4 modulates reversible and epigenetic silencing of the Cd4 gene.

Egawa T, Littman DR.

Proc Natl Acad Sci U S A. 2011 Sep 6;108(36):14873-8. doi: 10.1073/pnas.1112293108. Epub 2011 Aug 22.

4.

Morpholino antisense oligonucleotide-mediated gene knockdown during thymocyte development reveals role for Runx3 transcription factor in CD4 silencing during development of CD4-/CD8+ thymocytes.

Ehlers M, Laule-Kilian K, Petter M, Aldrian CJ, Grueter B, Würch A, Yoshida N, Watanabe T, Satake M, Steimle V.

J Immunol. 2003 Oct 1;171(7):3594-604.

5.

Differential requirements for Runx proteins in CD4 repression and epigenetic silencing during T lymphocyte development.

Taniuchi I, Osato M, Egawa T, Sunshine MJ, Bae SC, Komori T, Ito Y, Littman DR.

Cell. 2002 Nov 27;111(5):621-33.

6.

A silencer-proximal intronic region is required for sustained CD4 expression in postselection thymocytes.

Henson DM, Chou C, Sakurai N, Egawa T.

J Immunol. 2014 May 15;192(10):4620-7. doi: 10.4049/jimmunol.1302374. Epub 2014 Apr 11.

7.

CD4 regulation in human lymphoid non-T-cells: a role for the silencer element.

Mouly E, Dorival C, Pflumio F, Baillou C, Coulombel L, Levy Y, Lemoine FM, Klatzmann D, Marodon G.

Mol Immunol. 2007 Jan;44(4):267-75. Epub 2006 Apr 21.

PMID:
16630660
8.

Thymocytes control the CD4 gene differently from mature T lymphocytes.

Uematsu Y, Donda A, De Libero G.

Int Immunol. 1997 Jan;9(1):179-87.

PMID:
9043959
9.

Sequence and functional properties of African green monkey CD4 silencer.

Matsunaga S, Mukai R, Inoue-Murayama M, Yoshikawa Y, Murayama Y.

Immunol Lett. 2000 Dec 1;75(1):47-53.

PMID:
11163866
10.

Groucho/transducin-like Enhancer-of-split (TLE)-dependent and -independent transcriptional regulation by Runx3.

Yarmus M, Woolf E, Bernstein Y, Fainaru O, Negreanu V, Levanon D, Groner Y.

Proc Natl Acad Sci U S A. 2006 May 9;103(19):7384-9. Epub 2006 May 1.

11.

Evidence for distinct CD4 silencer functions at different stages of thymocyte differentiation.

Taniuchi I, Sunshine MJ, Festenstein R, Littman DR.

Mol Cell. 2002 Nov;10(5):1083-96.

12.

Epigenetic silencing of CD4 in T cells committed to the cytotoxic lineage.

Zou YR, Sunshine MJ, Taniuchi I, Hatam F, Killeen N, Littman DR.

Nat Genet. 2001 Nov;29(3):332-6.

PMID:
11687799
13.

Position-dependent variegation of a CD4 minigene with targeted expression to mature CD4+ T cells.

Boyer O, Zhao JC, Cohen JL, Depetris D, Yagello M, Lejeune L, Bruel S, Mattéï MG, Klatzmann D.

J Immunol. 1997 Oct 1;159(7):3383-90.

PMID:
9317137
14.

Epigenetic gene silencing by Runx proteins.

Taniuchi I, Littman DR.

Oncogene. 2004 May 24;23(24):4341-5. Review.

PMID:
15156191
15.

Epigenetic silencing of CD8 genes by ThPOK-mediated deacetylation during CD4 T cell differentiation.

Rui J, Liu H, Zhu X, Cui Y, Liu X.

J Immunol. 2012 Aug 1;189(3):1380-90. doi: 10.4049/jimmunol.1201077. Epub 2012 Jun 22.

16.

Runx3 regulates integrin alpha E/CD103 and CD4 expression during development of CD4-/CD8+ T cells.

Grueter B, Petter M, Egawa T, Laule-Kilian K, Aldrian CJ, Wuerch A, Ludwig Y, Fukuyama H, Wardemann H, Waldschuetz R, Möröy T, Taniuchi I, Steimle V, Littman DR, Ehlers M.

J Immunol. 2005 Aug 1;175(3):1694-705. Erratum in: J Immunol. 2005 Nov 1;175(9):6238.

17.

Characterization of an intronless CD4 minigene expressed in mature CD4 and CD8 T cells, but not expressed in immature thymocytes.

Salmon P, Boyer O, Lorès P, Jami J, Klatzmann D.

J Immunol. 1996 Mar 1;156(5):1873-9.

PMID:
8596039
18.

Negative regulation of CD4 expression in T cells by the transcriptional repressor ZEB.

Brabletz T, Jung A, Hlubek F, Löhberg C, Meiler J, Suchy U, Kirchner T.

Int Immunol. 1999 Oct;11(10):1701-8.

PMID:
10508188
19.

A lineage-specific transcriptional silencer regulates CD4 gene expression during T lymphocyte development.

Sawada S, Scarborough JD, Killeen N, Littman DR.

Cell. 1994 Jun 17;77(6):917-29.

PMID:
8004678
20.

The notch pathway intermediate HES-1 silences CD4 gene expression.

Kim HK, Siu G.

Mol Cell Biol. 1998 Dec;18(12):7166-75.

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