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Items: 1 to 20 of 122

1.

Heat shock protein 90 is critical for regulation of phenotype and functional activity of human T lymphocytes and NK cells.

Bae J, Munshi A, Li C, Samur M, Prabhala R, Mitsiades C, Anderson KC, Munshi NC.

J Immunol. 2013 Feb 1;190(3):1360-71. doi: 10.4049/jimmunol.1200593. Epub 2013 Jan 4.

2.

Heat shock protein 90 inhibitors induce functional inhibition of human natural killer cells in a dose-dependent manner.

Huyan T, Li Q, Dong DD, Yang H, Zhang J, Huang QS, Yin DC, Shang P.

Immunopharmacol Immunotoxicol. 2016;38(2):77-86. doi: 10.3109/08923973.2015.1119159. Epub 2015 Dec 8.

PMID:
26642940
4.

Heat shock protein-90 inhibitors increase MHC class I-related chain A and B ligand expression on multiple myeloma cells and their ability to trigger NK cell degranulation.

Fionda C, Soriani A, Malgarini G, Iannitto ML, Santoni A, Cippitelli M.

J Immunol. 2009 Oct 1;183(7):4385-94. doi: 10.4049/jimmunol.0901797. Epub 2009 Sep 11.

5.

Phenotypic and functional effects of heat shock protein 90 inhibition on dendritic cell.

Bae J, Mitsiades C, Tai YT, Bertheau R, Shammas M, Batchu RB, Li C, Catley L, Prabhala R, Anderson KC, Munshi NC.

J Immunol. 2007 Jun 15;178(12):7730-7.

6.

The Hsp90-specific inhibitor geldanamycin selectively disrupts kinase-mediated signaling events of T-lymphocyte activation.

Schnaider T, Somogyi J, Csermely P, Szamel M.

Cell Stress Chaperones. 2000 Jan;5(1):52-61.

7.

Effects of geldanamycin, a heat-shock protein 90-binding agent, on T cell function and T cell nonreceptor protein tyrosine kinases.

Yorgin PD, Hartson SD, Fellah AM, Scroggins BT, Huang W, Katsanis E, Couchman JM, Matts RL, Whitesell L.

J Immunol. 2000 Mar 15;164(6):2915-23.

8.

Selective expansion and partial activation of human NK cells and NK receptor-positive T cells by IL-2 and IL-15.

Dunne J, Lynch S, O'Farrelly C, Todryk S, Hegarty JE, Feighery C, Doherty DG.

J Immunol. 2001 Sep 15;167(6):3129-38.

10.

HLA class I-specific inhibitory receptors in human T lymphocytes: interleukin 15-induced expression of CD94/NKG2A in superantigen- or alloantigen-activated CD8+ T cells.

Mingari MC, Ponte M, Bertone S, Schiavetti F, Vitale C, Bellomo R, Moretta A, Moretta L.

Proc Natl Acad Sci U S A. 1998 Feb 3;95(3):1172-7.

11.

The heat-shock protein 90 inhibitor, geldanamycin, induces apoptotic cell death in Epstein-Barr virus-positive NK/T-cell lymphoma by Akt down-regulation.

Jeon YK, Park CH, Kim KY, Li YC, Kim J, Kim YA, Paik JH, Park BK, Kim CW, Kim YN.

J Pathol. 2007 Oct;213(2):170-9.

PMID:
17768706
12.

HSP90 is crucial for regulation of LAT expression in activated T cells.

Hayashi K, Kamikawa Y.

Mol Immunol. 2011 Mar;48(6-7):941-6. doi: 10.1016/j.molimm.2010.12.014. Epub 2011 Jan 20.

PMID:
21251717
13.

Selective depletion of alloreactive T cells by targeted therapy of heat shock protein 90: a novel strategy for control of graft-versus-host disease.

Stuehler C, Mielke S, Chatterjee M, Duell J, Lurati S, Rueckert F, Einsele H, Bargou RC, Topp MS.

Blood. 2009 Sep 24;114(13):2829-36. doi: 10.1182/blood-2009-06-224600. Epub 2009 Aug 5.

14.

Heat shock protein 90 inhibitor BIIB021 (CNF2024) depletes NF-kappaB and sensitizes Hodgkin's lymphoma cells for natural killer cell-mediated cytotoxicity.

Böll B, Eltaib F, Reiners KS, von Tresckow B, Tawadros S, Simhadri VR, Burrows FJ, Lundgren K, Hansen HP, Engert A, von Strandmann EP.

Clin Cancer Res. 2009 Aug 15;15(16):5108-16. doi: 10.1158/1078-0432.CCR-09-0213. Epub 2009 Aug 11.

15.

The Hsp90-specific inhibitor, geldanamycin, blocks CD28-mediated activation of human T lymphocytes.

Schnaider T, Somogyi J, Csermely P, Szamel M.

Life Sci. 1998;63(11):949-54.

PMID:
9747895
16.

p40 molecule regulates NK cell activation mediated by NK receptors for HLA class I antigens and TCR-mediated triggering of T lymphocytes.

Poggi A, Tomasello E, Revello V, Nanni L, Costa P, Moretta L.

Int Immunol. 1997 Sep;9(9):1271-9.

PMID:
9310830
17.

Histone deacetylase inhibitors impair NK cell viability and effector functions through inhibition of activation and receptor expression.

Rossi LE, Avila DE, Spallanzani RG, Ziblat A, Fuertes MB, Lapyckyj L, Croci DO, Rabinovich GA, Domaica CI, Zwirner NW.

J Leukoc Biol. 2012 Feb;91(2):321-31. doi: 10.1189/jlb.0711339. Epub 2011 Nov 28.

PMID:
22124136
18.

Activated gammadelta T cells express the natural cytotoxicity receptor natural killer p 44 and show cytotoxic activity against myeloma cells.

von Lilienfeld-Toal M, Nattermann J, Feldmann G, Sievers E, Frank S, Strehl J, Schmidt-Wolf IG.

Clin Exp Immunol. 2006 Jun;144(3):528-33.

19.

17-AAG and 17-DMAG-induced inhibition of cell proliferation through B-Raf downregulation in WT B-Raf-expressing uveal melanoma cell lines.

Babchia N, Calipel A, Mouriaux F, Faussat AM, Mascarelli F.

Invest Ophthalmol Vis Sci. 2008 Jun;49(6):2348-56. doi: 10.1167/iovs.07-1305. Epub 2008 Feb 15.

PMID:
18281615

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