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Items: 1 to 20 of 64

1.

A member of the Ras oncogene family, RAP1A, mediates antileishmanial activity of monastrol.

Kaur J, Dutta S, Chang KP, Singh N.

J Antimicrob Chemother. 2013 May;68(5):1071-80. doi: 10.1093/jac/dks507. Epub 2013 Jan 4.

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Antiproliferative activity of monastrol in human adenocarcinoma (MCF-7) and non-tumor (HB4a) breast cells.

Marques LA, Semprebon SC, Niwa AM, D'Epiro GF, Sartori D, de Fátima Â, Ribeiro LR, Mantovani MS.

Naunyn Schmiedebergs Arch Pharmacol. 2016 Dec;389(12):1279-1288. Epub 2016 Sep 3.

PMID:
27592117
4.

Dihydropyrido[2,3-d]pyrimidines as a new class of antileishmanial agents.

Agarwal A, Ramesh, Ashutosh, Goyal N, Chauhan PM, Gupta S.

Bioorg Med Chem. 2005 Dec 15;13(24):6678-84. Epub 2005 Aug 26.

PMID:
16126395
5.

Antileishmanial agents part-IV: synthesis and antileishmanial activity of novel terpenyl pyrimidines.

Chandra N, Ramesh, Ashutosh, Goyal N, Suryawanshi SN, Gupta S.

Eur J Med Chem. 2005 Jun;40(6):552-6.

PMID:
16003841
6.

Activity of LaSOM 65, a monastrol-derived compound, against glioblastoma multiforme cell lines.

Stuepp CS, Figueiró F, Mendes FB, Braganhol E, Bernardi A, Frozza RL, Salbego CG, Canto RF, Russowsky D, Eifler-Lima VL, Battastini AM.

Anticancer Res. 2013 Oct;33(10):4463-8.

PMID:
24123016
7.

Differential effects of monastrol in two human cell lines.

Leizerman I, Avunie-Masala R, Elkabets M, Fich A, Gheber L.

Cell Mol Life Sci. 2004 Aug;61(16):2060-70.

PMID:
15316655
8.

Synthesis and differential antiproliferative activity of Biginelli compounds against cancer cell lines: Monastrol, oxo-monastrol and oxygenated analogues.

Russowsky D, Canto RF, Sanches SA, D'Oca MG, de Fátima A, Pilli RA, Kohn LK, Antônio MA, de Carvalho JE.

Bioorg Chem. 2006 Aug;34(4):173-82. Epub 2006 Jun 12.

PMID:
16765411
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10.

Leishmania tarentolae: utility as an in vitro model for screening of antileishmanial agents.

Taylor VM, Muñoz DL, Cedeño DL, Vélez ID, Jones MA, Robledo SM.

Exp Parasitol. 2010 Dec;126(4):471-5. doi: 10.1016/j.exppara.2010.05.016. Epub 2010 May 26.

PMID:
20685203
11.

Comparison of the Effects of Monastrol and Oxomonastrol on Human Hepatoma Cell Line HepG2/C3A.

Marques LA, Semprebon SC, Sartori D, DE Fátima Â, Ribeiro LR, Mantovani MS.

Anticancer Res. 2017 Mar;37(3):1197-1204.

PMID:
28314282
12.

Preclinical and clinical pharmacodynamic assessment of L-778,123, a dual inhibitor of farnesyl:protein transferase and geranylgeranyl:protein transferase type-I.

Lobell RB, Liu D, Buser CA, Davide JP, DePuy E, Hamilton K, Koblan KS, Lee Y, Mosser S, Motzel SL, Abbruzzese JL, Fuchs CS, Rowinsky EK, Rubin EH, Sharma S, Deutsch PJ, Mazina KE, Morrison BW, Wildonger L, Yao SL, Kohl NE.

Mol Cancer Ther. 2002 Jul;1(9):747-58.

13.

In vitro antileishmanial activity of diphyllin isolated from Haplophyllum bucharicum.

Di Giorgio C, Delmas F, Akhmedjanova V, Ollivier E, Bessonova I, Riad E, Timon-David P.

Planta Med. 2005 Apr;71(4):366-9.

PMID:
15856417
14.

Structure/antileishmanial activity relationship study of naphthoquinones and dependency of the mode of action on the substitution patterns.

Ali A, Assimopoulou AN, Papageorgiou VP, Kolodziej H.

Planta Med. 2011 Dec;77(18):2003-12. doi: 10.1055/s-0031-1280092. Epub 2011 Jul 28.

PMID:
21800278
15.

Structure of human Eg5 in complex with a new monastrol-based inhibitor bound in the R configuration.

Garcia-Saez I, DeBonis S, Lopez R, Trucco F, Rousseau B, Thuéry P, Kozielski F.

J Biol Chem. 2007 Mar 30;282(13):9740-7. Epub 2007 Jan 23.

16.

Synthesis and antileishmanial profile of some novel terpenyl pyrimidines.

Pandey S, Suryawanshi SN, Gupta S, Srivastava VM.

Eur J Med Chem. 2004 Nov;39(11):969-73.

PMID:
15501546
17.

Nelfinavir, an HIV-1 protease inhibitor, induces oxidative stress-mediated, caspase-independent apoptosis in Leishmania amastigotes.

Kumar P, Lodge R, Trudel N, Ouellet M, Ouellette M, Tremblay MJ.

PLoS Negl Trop Dis. 2010 Mar 30;4(3):e642. doi: 10.1371/journal.pntd.0000642.

18.

Role of the ABC transporter PRP1 (ABCC7) in pentamidine resistance in Leishmania amastigotes.

Coelho AC, Messier N, Ouellette M, Cotrim PC.

Antimicrob Agents Chemother. 2007 Aug;51(8):3030-2. Epub 2007 Apr 23.

19.

Reactive oxygen species production and mitochondrial dysfunction contribute to quercetin induced death in Leishmania amazonensis.

Fonseca-Silva F, Inacio JD, Canto-Cavalheiro MM, Almeida-Amaral EE.

PLoS One. 2011 Feb 8;6(2):e14666. doi: 10.1371/journal.pone.0014666.

20.

Flavonoid dimers as novel, potent antileishmanial agents.

Wong IL, Chan KF, Chan TH, Chow LM.

J Med Chem. 2012 Oct 25;55(20):8891-902. doi: 10.1021/jm301172v. Epub 2012 Oct 3.

PMID:
22989363

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