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Items: 1 to 20 of 170

1.

Combined action of nucleic acid-sensing Toll-like receptors and TLR11/TLR12 heterodimers imparts resistance to Toxoplasma gondii in mice.

Andrade WA, Souza Mdo C, Ramos-Martinez E, Nagpal K, Dutra MS, Melo MB, Bartholomeu DC, Ghosh S, Golenbock DT, Gazzinelli RT.

Cell Host Microbe. 2013 Jan 16;13(1):42-53. doi: 10.1016/j.chom.2012.12.003. Epub 2013 Jan 3.

2.

UNC93B1 and nucleic acid-sensing Toll-like receptors mediate host resistance to infection with Leishmania major.

Schamber-Reis BL, Petritus PM, Caetano BC, Martinez ER, Okuda K, Golenbock D, Scott P, Gazzinelli RT.

J Biol Chem. 2013 Mar 8;288(10):7127-36. doi: 10.1074/jbc.M112.407684. Epub 2013 Jan 16.

3.

Naturally occurring Toll-like receptor 11 (TLR11) and Toll-like receptor 12 (TLR12) polymorphisms are not associated with Toxoplasma gondii infection in wild wood mice.

Morger J, Bajnok J, Boyce K, Craig PS, Rogan MT, Lun ZR, Hide G, Tschirren B.

Infect Genet Evol. 2014 Aug;26:180-4. doi: 10.1016/j.meegid.2014.05.032. Epub 2014 Jun 6.

PMID:
24910107
4.

Recognition of profilin by Toll-like receptor 12 is critical for host resistance to Toxoplasma gondii.

Koblansky AA, Jankovic D, Oh H, Hieny S, Sungnak W, Mathur R, Hayden MS, Akira S, Sher A, Ghosh S.

Immunity. 2013 Jan 24;38(1):119-30. doi: 10.1016/j.immuni.2012.09.016. Epub 2012 Dec 13.

5.

Requirement of UNC93B1 reveals a critical role for TLR7 in host resistance to primary infection with Trypanosoma cruzi.

Caetano BC, Carmo BB, Melo MB, Cerny A, dos Santos SL, Bartholomeu DC, Golenbock DT, Gazzinelli RT.

J Immunol. 2011 Aug 15;187(4):1903-11. doi: 10.4049/jimmunol.1003911. Epub 2011 Jul 13.

6.

Unc93B1 biases Toll-like receptor responses to nucleic acid in dendritic cells toward DNA- but against RNA-sensing.

Fukui R, Saitoh S, Matsumoto F, Kozuka-Hata H, Oyama M, Tabeta K, Beutler B, Miyake K.

J Exp Med. 2009 Jun 8;206(6):1339-50. doi: 10.1084/jem.20082316. Epub 2009 May 18.

7.

Cooperation of TLR12 and TLR11 in the IRF8-dependent IL-12 response to Toxoplasma gondii profilin.

Raetz M, Kibardin A, Sturge CR, Pifer R, Li H, Burstein E, Ozato K, Larin S, Yarovinsky F.

J Immunol. 2013 Nov 1;191(9):4818-27. doi: 10.4049/jimmunol.1301301. Epub 2013 Sep 27.

8.

UNC93B1 is essential for TLR11 activation and IL-12-dependent host resistance to Toxoplasma gondii.

Pifer R, Benson A, Sturge CR, Yarovinsky F.

J Biol Chem. 2011 Feb 4;286(5):3307-14. doi: 10.1074/jbc.M110.171025. Epub 2010 Nov 19.

9.

UNC93B1 mediates host resistance to infection with Toxoplasma gondii.

Melo MB, Kasperkovitz P, Cerny A, Könen-Waisman S, Kurt-Jones EA, Lien E, Beutler B, Howard JC, Golenbock DT, Gazzinelli RT.

PLoS Pathog. 2010 Aug 26;6(8):e1001071. doi: 10.1371/journal.ppat.1001071.

10.

Innate responses to Toxoplasma gondii in mice and humans.

Pifer R, Yarovinsky F.

Trends Parasitol. 2011 Sep;27(9):388-93. doi: 10.1016/j.pt.2011.03.009. Review.

11.

Toll road for Toxoplasma gondii: the mystery continues.

Khan IA.

Trends Parasitol. 2007 Jan;23(1):1-3. Epub 2006 Nov 2.

PMID:
17084106
12.

Recognition of Toxoplasma gondii by TLR11 prevents parasite-induced immunopathology.

Yarovinsky F, Hieny S, Sher A.

J Immunol. 2008 Dec 15;181(12):8478-84.

13.

Toll-like receptor 7 mediates early innate immune responses to malaria.

Baccarella A, Fontana MF, Chen EC, Kim CC.

Infect Immun. 2013 Dec;81(12):4431-42. doi: 10.1128/IAI.00923-13. Epub 2013 Sep 16.

14.

Innate resistance against Toxoplasma gondii: an evolutionary tale of mice, cats, and men.

Gazzinelli RT, Mendonça-Neto R, Lilue J, Howard J, Sher A.

Cell Host Microbe. 2014 Feb 12;15(2):132-8. doi: 10.1016/j.chom.2014.01.004. Review.

15.

Unmethylated CpG motifs in Toxoplasma gondii DNA induce TLR9- and IFN-β-dependent expression of α-defensin-5 in intestinal epithelial cells.

Santamaria MH, Perez Caballero E, Corral RS.

Parasitology. 2016 Jan;143(1):60-8. doi: 10.1017/S0031182015001456. Epub 2015 Nov 2.

PMID:
26522645
16.

TLR11 activation of dendritic cells by a protozoan profilin-like protein.

Yarovinsky F, Zhang D, Andersen JF, Bannenberg GL, Serhan CN, Hayden MS, Hieny S, Sutterwala FS, Flavell RA, Ghosh S, Sher A.

Science. 2005 Jun 10;308(5728):1626-9. Epub 2005 Apr 28.

17.

Unc93B1 restricts systemic lethal inflammation by orchestrating Toll-like receptor 7 and 9 trafficking.

Fukui R, Saitoh S, Kanno A, Onji M, Shibata T, Ito A, Onji M, Matsumoto M, Akira S, Yoshida N, Miyake K.

Immunity. 2011 Jul 22;35(1):69-81. doi: 10.1016/j.immuni.2011.05.010. Epub 2011 Jun 16.

18.

Gut commensal bacteria direct a protective immune response against Toxoplasma gondii.

Benson A, Pifer R, Behrendt CL, Hooper LV, Yarovinsky F.

Cell Host Microbe. 2009 Aug 20;6(2):187-96. doi: 10.1016/j.chom.2009.06.005.

19.

Structure-based analysis of Toxoplasma gondii profilin: a parasite-specific motif is required for recognition by Toll-like receptor 11.

Kucera K, Koblansky AA, Saunders LP, Frederick KB, De La Cruz EM, Ghosh S, Modis Y.

J Mol Biol. 2010 Nov 5;403(4):616-29. doi: 10.1016/j.jmb.2010.09.022. Epub 2010 Sep 17.

20.

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