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Items: 1 to 20 of 109

1.

Dynamin-related protein-1 controls fusion pore dynamics during platelet granule exocytosis.

Koseoglu S, Dilks JR, Peters CG, Fitch-Tewfik JL, Fadel NA, Jasuja R, Italiano JE Jr, Haynes CL, Flaumenhaft R.

Arterioscler Thromb Vasc Biol. 2013 Mar;33(3):481-8. doi: 10.1161/ATVBAHA.112.255737. Epub 2013 Jan 3.

2.

The Putative Drp1 Inhibitor mdivi-1 Is a Reversible Mitochondrial Complex I Inhibitor that Modulates Reactive Oxygen Species.

Bordt EA, Clerc P, Roelofs BA, Saladino AJ, Tretter L, Adam-Vizi V, Cherok E, Khalil A, Yadava N, Ge SX, Francis TC, Kennedy NW, Picton LK, Kumar T, Uppuluri S, Miller AM, Itoh K, Karbowski M, Sesaki H, Hill RB, Polster BM.

Dev Cell. 2017 Mar 27;40(6):583-594.e6. doi: 10.1016/j.devcel.2017.02.020.

PMID:
28350990
3.

Drp1 is dispensable for apoptotic cytochrome c release in primed MCF10A and fibroblast cells but affects Bcl-2 antagonist-induced respiratory changes.

Clerc P, Ge SX, Hwang H, Waddell J, Roelofs BA, Karbowski M, Sesaki H, Polster BM.

Br J Pharmacol. 2014 Apr;171(8):1988-99. doi: 10.1111/bph.12515.

4.

Quantal regulation and exocytosis of platelet dense-body granules.

Ge S, Woo E, Haynes CL.

Biophys J. 2011 Nov 16;101(10):2351-9. doi: 10.1016/j.bpj.2011.10.001. Epub 2011 Nov 15.

5.

A new role for the dynamin GTPase in the regulation of fusion pore expansion.

Anantharam A, Bittner MA, Aikman RL, Stuenkel EL, Schmid SL, Axelrod D, Holz RW.

Mol Biol Cell. 2011 Jun 1;22(11):1907-18. doi: 10.1091/mbc.E11-02-0101. Epub 2011 Apr 1.

6.

Dynamin-related protein 1 mediates low glucose-induced endothelial dysfunction in human arterioles.

Tanner MJ, Wang J, Ying R, Suboc TB, Malik M, Couillard A, Branum A, Puppala V, Widlansky ME.

Am J Physiol Heart Circ Physiol. 2017 Mar 1;312(3):H515-H527. doi: 10.1152/ajpheart.00499.2016. Epub 2016 Dec 6.

PMID:
27923790
7.

Small molecules demonstrate the role of dynamin as a bi-directional regulator of the exocytosis fusion pore and vesicle release.

Jackson J, Papadopulos A, Meunier FA, McCluskey A, Robinson PJ, Keating DJ.

Mol Psychiatry. 2015 Jul;20(7):810-9. doi: 10.1038/mp.2015.56. Epub 2015 May 5.

PMID:
25939402
8.

Platelets possess and require an active protein palmitoylation pathway for agonist-mediated activation and in vivo thrombus formation.

Sim DS, Dilks JR, Flaumenhaft R.

Arterioscler Thromb Vasc Biol. 2007 Jun;27(6):1478-85. Epub 2007 Feb 15.

9.

HRES-1/Rab4-mediated depletion of Drp1 impairs mitochondrial homeostasis and represents a target for treatment in SLE.

Caza TN, Fernandez DR, Talaber G, Oaks Z, Haas M, Madaio MP, Lai ZW, Miklossy G, Singh RR, Chudakov DM, Malorni W, Middleton F, Banki K, Perl A.

Ann Rheum Dis. 2014 Oct;73(10):1888-97. doi: 10.1136/annrheumdis-2013-203794. Epub 2013 Jul 29.

10.

Respective contributions of single and compound granule fusion to secretion by activated platelets.

Eckly A, Rinckel JY, Proamer F, Ulas N, Joshi S, Whiteheart SW, Gachet C.

Blood. 2016 Nov 24;128(21):2538-2549. Epub 2016 Sep 13.

PMID:
27625359
11.

Inhibition of platelet-mediated arterial thrombosis and platelet granule exocytosis by 3',4'-dihydroxyflavonol and quercetin.

Mosawy S, Jackson DE, Woodman OL, Linden MD.

Platelets. 2013;24(8):594-604. doi: 10.3109/09537104.2012.749396. Epub 2012 Dec 18.

PMID:
23249183
12.

Impact of the serum- and glucocorticoid-inducible kinase 1 on platelet dense granule biogenesis and secretion.

Walker B, Schmid E, Russo A, Schmidt EM, Burk O, Münzer P, Velic A, Macek B, Schaller M, Schwab M, Seabra MC, Gawaz M, Lang F, Borst O.

J Thromb Haemost. 2015 Jul;13(7):1325-34. doi: 10.1111/jth.12998. Epub 2015 Jun 12.

13.

Acid sphingomyelinase regulates platelet cell membrane scrambling, secretion, and thrombus formation.

Münzer P, Borst O, Walker B, Schmid E, Feijge MA, Cosemans JM, Chatterjee M, Schmidt EM, Schmidt S, Towhid ST, Leibrock C, Elvers M, Schaller M, Seizer P, Ferlinz K, May AE, Gulbins E, Heemskerk JW, Gawaz M, Lang F.

Arterioscler Thromb Vasc Biol. 2014 Jan;34(1):61-71. doi: 10.1161/ATVBAHA.112.300210. Epub 2013 Nov 14.

14.

Endobrevin/VAMP-8-dependent dense granule release mediates thrombus formation in vivo.

Graham GJ, Ren Q, Dilks JR, Blair P, Whiteheart SW, Flaumenhaft R.

Blood. 2009 Jul 30;114(5):1083-90. doi: 10.1182/blood-2009-03-210211. Epub 2009 Apr 24.

15.

Characterization of a novel function-blocking antibody targeted against the platelet P2Y1 receptor.

Karim ZA, Vemana HP, Alshbool FZ, Lin OA, Alshehri AM, Javaherizadeh P, Paez Espinosa EV, Khasawneh FT.

Arterioscler Thromb Vasc Biol. 2015 Mar;35(3):637-44. doi: 10.1161/ATVBAHA.114.304509. Epub 2015 Jan 15. Erratum in: Arterioscler Thromb Vasc Biol. 2015 Oct;35(10):e50.

16.

Defective PDI release from platelets and endothelial cells impairs thrombus formation in Hermansky-Pudlak syndrome.

Sharda A, Kim SH, Jasuja R, Gopal S, Flaumenhaft R, Furie BC, Furie B.

Blood. 2015 Mar 5;125(10):1633-42. doi: 10.1182/blood-2014-08-597419. Epub 2015 Jan 15.

17.

VAMP-7 links granule exocytosis to actin reorganization during platelet activation.

Koseoglu S, Peters CG, Fitch-Tewfik JL, Aisiku O, Danglot L, Galli T, Flaumenhaft R.

Blood. 2015 Jul 30;126(5):651-60. doi: 10.1182/blood-2014-12-618744. Epub 2015 May 21.

18.

Platelet secretory behaviour: as diverse as the granules … or not?

Heijnen H, van der Sluijs P.

J Thromb Haemost. 2015 Dec;13(12):2141-51. doi: 10.1111/jth.13147. Epub 2015 Oct 23. Review.

PMID:
26391322
19.

Anfibatide, a novel GPIb complex antagonist, inhibits platelet adhesion and thrombus formation in vitro and in vivo in murine models of thrombosis.

Lei X, Reheman A, Hou Y, Zhou H, Wang Y, Marshall AH, Liang C, Dai X, Li BX, Vanhoorelbeke K, Ni H.

Thromb Haemost. 2014 Feb;111(2):279-89. doi: 10.1160/TH13-06-0490. Epub 2013 Oct 31.

PMID:
24172860
20.

Involvement of Drp1 in hypoxia-induced migration of human glioblastoma U251 cells.

Wan YY, Zhang JF, Yang ZJ, Jiang LP, Wei YF, Lai QN, Wang JB, Xin HB, Han XJ.

Oncol Rep. 2014 Aug;32(2):619-26. doi: 10.3892/or.2014.3235. Epub 2014 Jun 5.

PMID:
24899388

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