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Items: 1 to 20 of 116

1.

Alterations in glutathione levels and apoptotic regulators are associated with acquisition of arsenic trioxide resistance in multiple myeloma.

Matulis SM, Morales AA, Yehiayan L, Lee KP, Cai Y, Boise LH.

PLoS One. 2012;7(12):e52662. doi: 10.1371/journal.pone.0052662. Epub 2012 Dec 21.

2.

Darinaparsin induces a unique cellular response and is active in an arsenic trioxide-resistant myeloma cell line.

Matulis SM, Morales AA, Yehiayan L, Croutch C, Gutman D, Cai Y, Lee KP, Boise LH.

Mol Cancer Ther. 2009 May;8(5):1197-206. doi: 10.1158/1535-7163.MCT-08-1072. Epub 2009 May 5.

4.

Ethacrynic acid and a derivative enhance apoptosis in arsenic trioxide-treated myeloid leukemia and lymphoma cells: the role of glutathione S-transferase p1-1.

Wang R, Liu C, Xia L, Zhao G, Gabrilove J, Waxman S, Jing Y.

Clin Cancer Res. 2012 Dec 15;18(24):6690-701. doi: 10.1158/1078-0432.CCR-12-0770. Epub 2012 Oct 18.

5.

BH3-only proteins Noxa, Bmf, and Bim are necessary for arsenic trioxide-induced cell death in myeloma.

Morales AA, Gutman D, Lee KP, Boise LH.

Blood. 2008 May 15;111(10):5152-62. doi: 10.1182/blood-2007-10-116889. Epub 2008 Mar 19.

6.

P38 MAPK inhibition enhancing ATO-induced cytotoxicity against multiple myeloma cells.

Wen J, Cheng HY, Feng Y, Rice L, Liu S, Mo A, Huang J, Zu Y, Ballon DJ, Chang CC.

Br J Haematol. 2008 Jan;140(2):169-80. doi: 10.1111/j.1365-2141.2007.06895.x.

PMID:
18173754
7.

Arsenic trioxide-mediated growth inhibition of myeloma cells is associated with an extrinsic or intrinsic signaling pathway through activation of TRAIL or TRAIL receptor 2.

Wu X, Shi J, Wu Y, Tao Y, Hou J, Meng X, Hu X, Han Y, Jiang W, Tang S, Zangari M, Tricot G, Zhan F.

Cancer Biol Ther. 2010 Dec 1;10(11):1201-14. Epub 2010 Dec 1.

8.

[Homoharringtonine combined arsenic trioxide induced apoptosis in human multiple myeloma cell line RPMI 8226: an experimental research].

Zhou XJ, Zhou YH, Chen XH, Qian WB.

Zhongguo Zhong Xi Yi Jie He Za Zhi. 2013 Jun;33(6):834-9. Chinese.

PMID:
23980369
9.

Combination of arsenic trioxide and chemotherapy in small cell lung cancer.

Zheng CY, Lam SK, Li YY, Fong BM, Mak JC, Ho JC.

Lung Cancer. 2013 Nov;82(2):222-30. doi: 10.1016/j.lungcan.2013.08.022. Epub 2013 Sep 3.

PMID:
24041618
10.

Quercetin decreases intracellular GSH content and potentiates the apoptotic action of the antileukemic drug arsenic trioxide in human leukemia cell lines.

Ramos AM, Aller P.

Biochem Pharmacol. 2008 May 15;75(10):1912-23. doi: 10.1016/j.bcp.2008.02.007. Epub 2008 Feb 16.

PMID:
18359480
13.

Proteomic and functional analyses reveal a dual molecular mechanism underlying arsenic-induced apoptosis in human multiple myeloma cells.

Ge F, Lu XP, Zeng HL, He QY, Xiong S, Jin L, He QY.

J Proteome Res. 2009 Jun;8(6):3006-19. doi: 10.1021/pr9001004.

PMID:
19364129
14.

Arsenic trioxide-induced cytotoxicity in small cell lung cancer via altered redox homeostasis and mitochondrial integrity.

Zheng CY, Lam SK, Li YY, Ho JC.

Int J Oncol. 2015 Mar;46(3):1067-78. doi: 10.3892/ijo.2015.2826. Epub 2015 Jan 9.

PMID:
25572414
15.

Potentiation of arsenic trioxide-induced apoptosis by 8-bromo-7-methoxychrysin in human leukemia cells involves depletion of intracellular reduced glutathione.

Xiao G, Tang X, Yao C, Wang C.

Acta Biochim Biophys Sin (Shanghai). 2011 Sep;43(9):712-21. doi: 10.1093/abbs/gmr065. Epub 2011 Jul 23.

PMID:
21785114
16.

Arsenic trioxide inhibits the growth of adriamycin resistant osteosarcoma cells through inducing apoptosis.

Zhao H, Guo W, Peng C, Ji T, Lu X.

Mol Biol Rep. 2010 Jun;37(5):2509-15. doi: 10.1007/s11033-009-9765-2. Epub 2009 Aug 22.

PMID:
19701692
17.

Arsenic trioxide inhibits the growth of Calu-6 cells via inducing a G2 arrest of the cell cycle and apoptosis accompanied with the depletion of GSH.

Han YH, Kim SZ, Kim SH, Park WH.

Cancer Lett. 2008 Oct 18;270(1):40-55. doi: 10.1016/j.canlet.2008.04.041. Epub 2008 Jun 9.

PMID:
18539383
18.

Arsenic trioxide induces Noxa-dependent apoptosis in rhabdomyosarcoma cells and synergizes with antimicrotubule drugs.

Meister MT, Boedicker C, Graab U, Hugle M, Hahn H, Klingebiel T, Fulda S.

Cancer Lett. 2016 Oct 28;381(2):287-95. doi: 10.1016/j.canlet.2016.07.007. Epub 2016 Aug 10.

PMID:
27521572
19.

Arsenic trioxide induces human pulmonary fibroblast cell death via increasing ROS levels and GSH depletion.

You BR, Park WH.

Oncol Rep. 2012 Aug;28(2):749-57. doi: 10.3892/or.2012.1852. Epub 2012 Jun 6.

PMID:
22684917
20.

Molecular targets of arsenic trioxide in malignant cells.

Miller WH Jr.

Oncologist. 2002;7 Suppl 1:14-9. Review.

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