Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 118

1.

Small molecule targeting Cdc42-intersectin interaction disrupts Golgi organization and suppresses cell motility.

Friesland A, Zhao Y, Chen YH, Wang L, Zhou H, Lu Q.

Proc Natl Acad Sci U S A. 2013 Jan 22;110(4):1261-6. doi: 10.1073/pnas.1116051110. Epub 2013 Jan 2.

2.

A Cdc42 mutant specifically activated by intersectin.

Smith WJ, Hamel B, Yohe ME, Sondek J, Cerione RA, Snyder JT.

Biochemistry. 2005 Oct 11;44(40):13282-90.

PMID:
16201754
3.
4.

Mechanisms of guanine nucleotide exchange and Rac-mediated signaling revealed by a dominant negative trio mutant.

Debreceni B, Gao Y, Guo F, Zhu K, Jia B, Zheng Y.

J Biol Chem. 2004 Jan 30;279(5):3777-86. Epub 2003 Nov 3.

5.

Characterization of a Cdc42 protein inhibitor and its use as a molecular probe.

Hong L, Kenney SR, Phillips GK, Simpson D, Schroeder CE, Nöth J, Romero E, Swanson S, Waller A, Strouse JJ, Carter M, Chigaev A, Ursu O, Oprea T, Hjelle B, Golden JE, Aubé J, Hudson LG, Buranda T, Sklar LA, Wandinger-Ness A.

J Biol Chem. 2013 Mar 22;288(12):8531-43. doi: 10.1074/jbc.M112.435941. Epub 2013 Feb 4. Erratum in: J Biol Chem. 2014 Mar 7;289(10):6837.

6.

A Rac/Cdc42-specific exchange factor, GEFT, induces cell proliferation, transformation, and migration.

Guo X, Stafford LJ, Bryan B, Xia C, Ma W, Wu X, Liu D, Songyang Z, Liu M.

J Biol Chem. 2003 Apr 11;278(15):13207-15. Epub 2003 Jan 23.

7.

Novel Activities of Select NSAID R-Enantiomers against Rac1 and Cdc42 GTPases.

Oprea TI, Sklar LA, Agola JO, Guo Y, Silberberg M, Roxby J, Vestling A, Romero E, Surviladze Z, Murray-Krezan C, Waller A, Ursu O, Hudson LG, Wandinger-Ness A.

PLoS One. 2015 Nov 11;10(11):e0142182. doi: 10.1371/journal.pone.0142182. eCollection 2015.

8.
9.

The guanine nucleotide exchange factor Tiam1: a Janus-faced molecule in cellular signaling.

Boissier P, Huynh-Do U.

Cell Signal. 2014 Mar;26(3):483-91. doi: 10.1016/j.cellsig.2013.11.034. Epub 2013 Dec 2. Review.

PMID:
24308970
10.

Intersectin-2L regulates caveola endocytosis secondary to Cdc42-mediated actin polymerization.

Klein IK, Predescu DN, Sharma T, Knezevic I, Malik AB, Predescu S.

J Biol Chem. 2009 Sep 18;284(38):25953-61. doi: 10.1074/jbc.M109.035071. Epub 2009 Jul 21.

11.

Molecular basis for Rac1 recognition by guanine nucleotide exchange factors.

Karnoub AE, Worthylake DK, Rossman KL, Pruitt WM, Campbell SL, Sondek J, Der CJ.

Nat Struct Biol. 2001 Dec;8(12):1037-41.

PMID:
11685227
12.

Crystal structure of human Intersectin-2L C2 domain.

Zhang W, Shen Y, Xiong G, Guo Y, Deng L, Li B, Yang J, Qi C.

Biochem Biophys Res Commun. 2013 Feb 1;431(1):76-80. doi: 10.1016/j.bbrc.2012.12.087. Epub 2012 Dec 27.

PMID:
23274495
13.

Selective activation by the guanine nucleotide exchange factor Don1 is a main determinant of Cdc42 signalling specificity in Ustilago maydis.

Hlubek A, Schink KO, Mahlert M, Sandrock B, Bölker M.

Mol Microbiol. 2008 May;68(3):615-23. doi: 10.1111/j.1365-2958.2008.06177.x.

14.

Trp(56) of rac1 specifies interaction with a subset of guanine nucleotide exchange factors.

Gao Y, Xing J, Streuli M, Leto TL, Zheng Y.

J Biol Chem. 2001 Dec 14;276(50):47530-41. Epub 2001 Oct 10. Erratum in: J Biol Chem. 2005 Jan 14;280(2):1704.

15.

Cdc42 and Ras cooperate to mediate cellular transformation by intersectin-L.

Wang JB, Wu WJ, Cerione RA.

J Biol Chem. 2005 Jun 17;280(24):22883-91. Epub 2005 Apr 11.

16.

Structure-function based design of small molecule inhibitors targeting Rho family GTPases.

Nassar N, Cancelas J, Zheng J, Williams DA, Zheng Y.

Curr Top Med Chem. 2006;6(11):1109-16. Review.

PMID:
16842149
17.
18.

Secramine inhibits Cdc42-dependent functions in cells and Cdc42 activation in vitro.

Pelish HE, Peterson JR, Salvarezza SB, Rodriguez-Boulan E, Chen JL, Stamnes M, Macia E, Feng Y, Shair MD, Kirchhausen T.

Nat Chem Biol. 2006 Jan;2(1):39-46. Epub 2005 Nov 20. Erratum in: Nat Chem Biol. 2006 Apr;2(4):221.

PMID:
16408091
19.

Identification and Characterization of a Novel Broad-Spectrum Virus Entry Inhibitor.

Chou YY, Cuevas C, Carocci M, Stubbs SH, Ma M, Cureton DK, Chao L, Evesson F, He K, Yang PL, Whelan SP, Ross SR, Kirchhausen T, Gaudin R.

J Virol. 2016 Apr 14;90(9):4494-510. doi: 10.1128/JVI.00103-16. Print 2016 May.

20.

GC-GAP, a Rho family GTPase-activating protein that interacts with signaling adapters Gab1 and Gab2.

Zhao C, Ma H, Bossy-Wetzel E, Lipton SA, Zhang Z, Feng GS.

J Biol Chem. 2003 Sep 5;278(36):34641-53. Epub 2003 Jun 19.

Supplemental Content

Support Center