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Items: 1 to 20 of 90


Action of nicotine and analogs on acetylcholine receptors having mutations of transmitter-binding site residue αG153.

Jadey S, Purohit P, Auerbach A.

J Gen Physiol. 2013 Jan;141(1):95-104. doi: 10.1085/jgp.201210896.


The role of loop 5 in acetylcholine receptor channel gating.

Chakrapani S, Bailey TD, Auerbach A.

J Gen Physiol. 2003 Nov;122(5):521-39. Epub 2003 Oct 13.


Acetylcholine receptor channels activated by a single agonist molecule.

Jha A, Auerbach A.

Biophys J. 2010 May 19;98(9):1840-6. doi: 10.1016/j.bpj.2010.01.025.


Unliganded gating of acetylcholine receptor channels.

Purohit P, Auerbach A.

Proc Natl Acad Sci U S A. 2009 Jan 6;106(1):115-20. doi: 10.1073/pnas.0809272106. Epub 2008 Dec 29.


The intrinsic energy of the gating isomerization of a neuromuscular acetylcholine receptor channel.

Nayak TK, Purohit PG, Auerbach A.

J Gen Physiol. 2012 May;139(5):349-58. doi: 10.1085/jgp.201110752.


Design and control of acetylcholine receptor conformational change.

Jadey SV, Purohit P, Bruhova I, Gregg TM, Auerbach A.

Proc Natl Acad Sci U S A. 2011 Mar 15;108(11):4328-33. doi: 10.1073/pnas.1016617108. Epub 2011 Mar 1.


Expression and channel properties of alpha-bungarotoxin-sensitive acetylcholine receptors on chick ciliary and choroid neurons.

McNerney ME, Pardi D, Pugh PC, Nai Q, Margiotta JF.

J Neurophysiol. 2000 Sep;84(3):1314-29.


Chronic nicotine treatment up-regulates human alpha3 beta2 but not alpha3 beta4 acetylcholine receptors stably transfected in human embryonic kidney cells.

Wang F, Nelson ME, Kuryatov A, Olale F, Cooper J, Keyser K, Lindstrom J.

J Biol Chem. 1998 Oct 30;273(44):28721-32.


Asymmetric transmitter binding sites of fetal muscle acetylcholine receptors shape their synaptic response.

Nayak TK, Auerbach A.

Proc Natl Acad Sci U S A. 2013 Aug 13;110(33):13654-9. doi: 10.1073/pnas.1308247110. Epub 2013 Jul 29.


Mutation of the acetylcholine receptor alpha subunit causes a slow-channel myasthenic syndrome by enhancing agonist binding affinity.

Sine SM, Ohno K, Bouzat C, Auerbach A, Milone M, Pruitt JN, Engel AG.

Neuron. 1995 Jul;15(1):229-39.


Contribution of valine 7' of TMD2 to gating of neuronal alpha3 receptor subtypes.

Nieves-Cintrón M, Caballero-Rivera D, Navedo MF, Lasalde-Dominicci JA.

J Neurosci Res. 2006 Dec;84(8):1778-88.


α1F64 Residue at GABA(A) receptor binding site is involved in gating by influencing the receptor flipping transitions.

Szczot M, Kisiel M, Czyzewska MM, Mozrzymas JW.

J Neurosci. 2014 Feb 26;34(9):3193-209. doi: 10.1523/JNEUROSCI.2533-13.2014. Erratum in: J Neurosci. 2016 Feb 10;36(6):2074.


Mutation in the M1 domain of the acetylcholine receptor alpha subunit decreases the rate of agonist dissociation.

Wang HL, Auerbach A, Bren N, Ohno K, Engel AG, Sine SM.

J Gen Physiol. 1997 Jun;109(6):757-66. Erratum in: J Gen Physiol 1997 Aug;110(2):215.


Mechanism of verapamil action on wild-type and slow-channel mutant human muscle acetylcholine receptor.

Moriconi C, Di Castro MA, Fucile S, Eusebi F, Grassi F.

J Neurochem. 2010 Aug;114(4):1231-40. doi: 10.1111/j.1471-4159.2010.06842.x. Epub 2010 Jun 1.

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