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Items: 1 to 20 of 325

1.

Ursolic acid promotes the neuroprotection by activating Nrf2 pathway after cerebral ischemia in mice.

Li L, Zhang X, Cui L, Wang L, Liu H, Ji H, Du Y.

Brain Res. 2013 Feb 25;1497:32-9. doi: 10.1016/j.brainres.2012.12.032. Epub 2012 Dec 28.

PMID:
23276496
2.

Curcumin upregulates transcription factor Nrf2, HO-1 expression and protects rat brains against focal ischemia.

Yang C, Zhang X, Fan H, Liu Y.

Brain Res. 2009 Jul 28;1282:133-41. doi: 10.1016/j.brainres.2009.05.009. Epub 2009 May 13.

PMID:
19445907
3.

S-allyl cysteine activates the Nrf2-dependent antioxidant response and protects neurons against ischemic injury in vitro and in vivo.

Shi H, Jing X, Wei X, Perez RG, Ren M, Zhang X, Lou H.

J Neurochem. 2015 Apr;133(2):298-308. doi: 10.1111/jnc.12986. Epub 2015 Jan 23.

4.

Sulforaphane preconditioning of the Nrf2/HO-1 defense pathway protects the cerebral vasculature against blood-brain barrier disruption and neurological deficits in stroke.

Alfieri A, Srivastava S, Siow RC, Cash D, Modo M, Duchen MR, Fraser PA, Williams SC, Mann GE.

Free Radic Biol Med. 2013 Dec;65:1012-22. doi: 10.1016/j.freeradbiomed.2013.08.190. Epub 2013 Sep 7.

PMID:
24017972
5.

Neuroprotection by acetyl-11-keto-β-Boswellic acid, in ischemic brain injury involves the Nrf2/HO-1 defense pathway.

Ding Y, Chen M, Wang M, Wang M, Zhang T, Park J, Zhu Y, Guo C, Jia Y, Li Y, Wen A.

Sci Rep. 2014 Nov 11;4:7002. doi: 10.1038/srep07002.

6.

Ursolic Acid Ameliorates Early Brain Injury After Experimental Traumatic Brain Injury in Mice by Activating the Nrf2 Pathway.

Ding H, Wang H, Zhu L, Wei W.

Neurochem Res. 2017 Feb;42(2):337-346. doi: 10.1007/s11064-016-2077-8. Epub 2016 Oct 12.

PMID:
27734181
7.

ATF3-mediated NRF2/HO-1 signaling regulates TLR4 innate immune responses in mouse liver ischemia/reperfusion injury.

Rao J, Qian X, Li G, Pan X, Zhang C, Zhang F, Zhai Y, Wang X, Lu L.

Am J Transplant. 2015 Jan;15(1):76-87. doi: 10.1111/ajt.12954. Epub 2014 Oct 30.

8.

Posttreatment with 11-Keto-β-Boswellic Acid Ameliorates Cerebral Ischemia-Reperfusion Injury: Nrf2/HO-1 Pathway as a Potential Mechanism.

Ding Y, Chen M, Wang M, Li Y, Wen A.

Mol Neurobiol. 2015 Dec;52(3):1430-1439. doi: 10.1007/s12035-014-8929-9. Epub 2014 Oct 28.

PMID:
25452227
9.

Bicyclol upregulates transcription factor Nrf2, HO-1 expression and protects rat brains against focal ischemia.

Zhang J, Fu B, Zhang X, Zhang L, Bai X, Zhao X, Chen L, Cui L, Zhu C, Wang L, Zhao Y, Zhao T, Wang X.

Brain Res Bull. 2014 Jan;100:38-43. doi: 10.1016/j.brainresbull.2013.11.001. Epub 2013 Nov 16.

PMID:
24252362
10.

Andrographolide stimulates p38 mitogen-activated protein kinase-nuclear factor erythroid-2-related factor 2-heme oxygenase 1 signaling in primary cerebral endothelial cells for definite protection against ischemic stroke in rats.

Yen TL, Chen RJ, Jayakumar T, Lu WJ, Hsieh CY, Hsu MJ, Yang CH, Chang CC, Lin YK, Lin KH, Sheu JR.

Transl Res. 2016 Apr;170:57-72. doi: 10.1016/j.trsl.2015.12.002. Epub 2015 Dec 17.

PMID:
26746802
11.

Carbon monoxide-activated Nrf2 pathway leads to protection against permanent focal cerebral ischemia.

Wang B, Cao W, Biswal S, Doré S.

Stroke. 2011 Sep;42(9):2605-10. doi: 10.1161/STROKEAHA.110.607101. Epub 2011 Aug 18.

12.

Tissue kallikrein protects against ischemic stroke by suppressing TLR4/NF-κB and activating Nrf2 signaling pathway in rats.

Yang J, Su J, Wan F, Yang N, Jiang H, Fang M, Xiao H, Wang J, Tang J.

Exp Ther Med. 2017 Aug;14(2):1163-1170. doi: 10.3892/etm.2017.4614. Epub 2017 Jun 15.

13.

Ruscogenin reduces cerebral ischemic injury via NF-κB-mediated inflammatory pathway in the mouse model of experimental stroke.

Guan T, Liu Q, Qian Y, Yang H, Kong J, Kou J, Yu B.

Eur J Pharmacol. 2013 Aug 15;714(1-3):303-11. doi: 10.1016/j.ejphar.2013.07.036. Epub 2013 Jul 30.

PMID:
23911884
14.

The protection by octreotide against experimental ischemic stroke: up-regulated transcription factor Nrf2, HO-1 and down-regulated NF-κB expression.

Chen L, Wang L, Zhang X, Cui L, Xing Y, Dong L, Liu Z, Li Y, Zhang X, Wang C, Bai X, Zhang J, Zhang L, Zhao X.

Brain Res. 2012 Sep 26;1475:80-7. doi: 10.1016/j.brainres.2012.07.052. Epub 2012 Aug 1.

PMID:
22885292
15.

A novel nuclear factor erythroid 2-related factor 2 (Nrf2) activator RS9 attenuates brain injury after ischemia reperfusion in mice.

Yamauchi K, Nakano Y, Imai T, Takagi T, Tsuruma K, Shimazawa M, Iwama T, Hara H.

Neuroscience. 2016 Oct 1;333:302-10. doi: 10.1016/j.neuroscience.2016.07.035. Epub 2016 Jul 27.

PMID:
27474227
16.

Paeonol pretreatment attenuates cerebral ischemic injury via upregulating expression of pAkt, Nrf2, HO-1 and ameliorating BBB permeability in mice.

Zhao Y, Fu B, Zhang X, Zhao T, Chen L, Zhang J, Wang X.

Brain Res Bull. 2014 Oct;109:61-7. doi: 10.1016/j.brainresbull.2014.09.008. Epub 2014 Oct 5.

PMID:
25286445
17.

Curcumin by down-regulating NF-kB and elevating Nrf2, reduces brain edema and neurological dysfunction after cerebral I/R.

Li W, Suwanwela NC, Patumraj S.

Microvasc Res. 2016 Jul;106:117-27. doi: 10.1016/j.mvr.2015.12.008. Epub 2015 Dec 12.

PMID:
26686249
18.

Z-ligustilide activates the Nrf2/HO-1 pathway and protects against cerebral ischemia-reperfusion injury in vivo and in vitro.

Peng B, Zhao P, Lu YP, Chen MM, Sun H, Wu XM, Zhu L.

Brain Res. 2013 Jul 3;1520:168-77. doi: 10.1016/j.brainres.2013.05.009. Epub 2013 May 18.

PMID:
23688544
20.

Histone deacetylase inhibition activates transcription factor Nrf2 and protects against cerebral ischemic damage.

Wang B, Zhu X, Kim Y, Li J, Huang S, Saleem S, Li RC, Xu Y, Dore S, Cao W.

Free Radic Biol Med. 2012 Mar 1;52(5):928-36. doi: 10.1016/j.freeradbiomed.2011.12.006. Epub 2011 Dec 17.

PMID:
22226832

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