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NADPH:quinone oxidoreductase 1 regulates host susceptibility to ozone via isoprostane generation.

Kummarapurugu AB, Fischer BM, Zheng S, Milne GL, Ghio AJ, Potts-Kant EN, Foster WM, Soderblom EJ, Dubois LG, Moseley MA, Thompson JW, Voynow JA.

J Biol Chem. 2013 Feb 15;288(7):4681-91. doi: 10.1074/jbc.M112.438440. Epub 2012 Dec 28.


NAD(P)H quinone oxidoreductase 1 is essential for ozone-induced oxidative stress in mice and humans.

Voynow JA, Fischer BM, Zheng S, Potts EN, Grover AR, Jaiswal AK, Ghio AJ, Foster WM.

Am J Respir Cell Mol Biol. 2009 Jul;41(1):107-13. doi: 10.1165/rcmb.2008-0381OC. Epub 2008 Dec 4. Erratum in: Am J Respir Cell Mol Biol. 2016 Dec;55(6):909.


NAD(P)H quinone oxidoreductase 1 regulates neutrophil elastase-induced mucous cell metaplasia.

Meyer ML, Potts-Kant EN, Ghio AJ, Fischer BM, Foster WM, Voynow JA.

Am J Physiol Lung Cell Mol Physiol. 2012 Aug 1;303(3):L181-8. doi: 10.1152/ajplung.00084.2012. Epub 2012 Jun 1. Erratum in: Am J Physiol Lung Cell Mol Physiol. 2015 Jul 1;309(1):L98.


NQO1 suppresses NF-κB-p300 interaction to regulate inflammatory mediators associated with prostate tumorigenesis.

Thapa D, Meng P, Bedolla RG, Reddick RL, Kumar AP, Ghosh R.

Cancer Res. 2014 Oct 1;74(19):5644-55. doi: 10.1158/0008-5472.CAN-14-0562. Epub 2014 Aug 14.


Genetic evidence for NAD(P)H:quinone oxidoreductase 1-catalyzed quinone reduction on passage through the mouse pulmonary circulation.

Lindemer BJ, Bongard RD, Hoffmann R, Baumgardt S, Gonzalez FJ, Merker MP.

Am J Physiol Lung Cell Mol Physiol. 2011 May;300(5):L773-80. doi: 10.1152/ajplung.00394.2010. Epub 2011 Feb 4.


NQO1 and NQO2 regulation of humoral immunity and autoimmunity.

Iskander K, Li J, Han S, Zheng B, Jaiswal AK.

J Biol Chem. 2006 Oct 13;281(41):30917-24. Epub 2006 Aug 10. Erratum in: J Biol Chem. 2017 Feb 3;292(5):2053.


Protective role of NAD(P)H:quinone oxidoreductase 1 (NQO1) in cisplatin-induced nephrotoxicity.

Gang GT, Kim YH, Noh JR, Kim KS, Jung JY, Shong M, Hwang JH, Lee CH.

Toxicol Lett. 2013 Aug 29;221(3):165-75. doi: 10.1016/j.toxlet.2013.06.239. Epub 2013 Jul 4.


Environmental pollutant and potent mutagen 3-nitrobenzanthrone forms DNA adducts after reduction by NAD(P)H:quinone oxidoreductase and conjugation by acetyltransferases and sulfotransferases in human hepatic cytosols.

Arlt VM, Stiborova M, Henderson CJ, Osborne MR, Bieler CA, Frei E, Martinek V, Sopko B, Wolf CR, Schmeiser HH, Phillips DH.

Cancer Res. 2005 Apr 1;65(7):2644-52.


NAD(P)H:quinone oxidoreductase 1: role as a superoxide scavenger.

Siegel D, Gustafson DL, Dehn DL, Han JY, Boonchoong P, Berliner LJ, Ross D.

Mol Pharmacol. 2004 May;65(5):1238-47.


Role of NAD(P)H:quinone oxidoreductase 1 (DT diaphorase) in protection against quinone toxicity.

Joseph P, Long DJ 2nd, Klein-Szanto AJ, Jaiswal AK.

Biochem Pharmacol. 2000 Jul 15;60(2):207-14.


Protection of NAD(P)H:quinone oxidoreductase 1 against renal ischemia/reperfusion injury in mice.

Gang GT, Hwang JH, Kim YH, Noh JR, Kim KS, Jeong JY, Choi DE, Lee KW, Jung JY, Shong M, Lee CH.

Free Radic Biol Med. 2014 Feb;67:139-49. doi: 10.1016/j.freeradbiomed.2013.10.817. Epub 2013 Nov 1.


Prevention of salt-induced renal injury by activation of NAD(P)H:quinone oxidoreductase 1, associated with NADPH oxidase.

Kim YH, Hwang JH, Noh JR, Gang GT, Tadi S, Yim YH, Jeoung NH, Kwak TH, Lee SH, Kweon GR, Kim JM, Shong M, Lee IK, Lee CH.

Free Radic Biol Med. 2012 Mar 1;52(5):880-8. doi: 10.1016/j.freeradbiomed.2011.12.007. Epub 2011 Dec 20.


Induction of NAD(P)H:quinone oxidoreductase 1 expression by cysteine via Nrf2 activation in human intestinal epithelial LS180 cells.

Satsu H, Chidachi E, Hiura Y, Ogiwara H, Gondo Y, Shimizu M.

Amino Acids. 2012 Oct;43(4):1547-555.


Coenzyme Q(1) as a probe for mitochondrial complex I activity in the intact perfused hyperoxia-exposed wild-type and Nqo1-null mouse lung.

Bongard RD, Myers CR, Lindemer BJ, Baumgardt S, Gonzalez FJ, Merker MP.

Am J Physiol Lung Cell Mol Physiol. 2012 May 1;302(9):L949-58. doi: 10.1152/ajplung.00251.2011. Epub 2012 Jan 20.


Beta-lapachone suppresses radiation-induced activation of nuclear factor-kappaB.

Dong GZ, Oh ET, Lee H, Park MT, Song CW, Park HJ.

Exp Mol Med. 2010 May 31;42(5):327-34.


Klotho expression is reduced in COPD airway epithelial cells: effects on inflammation and oxidant injury.

Gao W, Yuan C, Zhang J, Li L, Yu L, Wiegman CH, Barnes PJ, Adcock IM, Huang M, Yao X.

Clin Sci (Lond). 2015 Dec;129(12):1011-23. doi: 10.1042/CS20150273. Epub 2015 Jul 10.

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