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Items: 1 to 20 of 93

1.

Selective serotonin reuptake inhibitors (SSRIs) inhibit insulin secretion and action in pancreatic β cells.

Isaac R, Boura-Halfon S, Gurevitch D, Shainskaya A, Levkovitz Y, Zick Y.

J Biol Chem. 2013 Feb 22;288(8):5682-93. doi: 10.1074/jbc.M112.408641. Epub 2012 Dec 28.

2.

Antidepressants induce cellular insulin resistance by activation of IRS-1 kinases.

Levkovitz Y, Ben-Shushan G, Hershkovitz A, Isaac R, Gil-Ad I, Shvartsman D, Ronen D, Weizman A, Zick Y.

Mol Cell Neurosci. 2007 Nov;36(3):305-12. Epub 2007 Jun 29.

PMID:
17728140
3.
4.

Selective serotonin reuptake inhibitors directly signal for apoptosis in biopsy-like Burkitt lymphoma cells.

Serafeim A, Holder MJ, Grafton G, Chamba A, Drayson MT, Luong QT, Bunce CM, Gregory CD, Barnes NM, Gordon J.

Blood. 2003 Apr 15;101(8):3212-9. Epub 2002 Dec 19.

6.

ER stress in adipocytes inhibits insulin signaling, represses lipolysis, and alters the secretion of adipokines without inhibiting glucose transport.

Xu L, Spinas GA, Niessen M.

Horm Metab Res. 2010 Aug;42(9):643-51. doi: 10.1055/s-0030-1255034. Epub 2010 Jun 17.

7.

In vivo identification and characterization of binding sites for selective serotonin reuptake inhibitors in mouse brain.

Hirano K, Maruyama S, Kimura R, Kagawa Y, Yamada S.

Life Sci. 2004 Oct 29;75(24):2933-45.

PMID:
15454344
8.

Selective serotonin reuptake inhibitors reduce the spontaneous activity of dopaminergic neurons in the ventral tegmental area.

Di Mascio M, Di Giovanni G, Di Matteo V, Prisco S, Esposito E.

Brain Res Bull. 1998 Aug;46(6):547-54.

PMID:
9744293
9.

Evaluation of the potential anti-cancer activity of the antidepressant sertraline in human colon cancer cell lines and in colorectal cancer-xenografted mice.

Gil-Ad I, Zolokov A, Lomnitski L, Taler M, Bar M, Luria D, Ram E, Weizman A.

Int J Oncol. 2008 Aug;33(2):277-86.

PMID:
18636148
10.

Relationship between brain serotonin transporter binding, plasma concentration and behavioural effect of selective serotonin reuptake inhibitors.

Hirano K, Kimura R, Sugimoto Y, Yamada J, Uchida S, Kato Y, Hashimoto H, Yamada S.

Br J Pharmacol. 2005 Mar;144(5):695-702.

11.

Physiological concentrations of interleukin-6 directly promote insulin secretion, signal transduction, nitric oxide release, and redox status in a clonal pancreatic β-cell line and mouse islets.

da Silva Krause M, Bittencourt A, Homem de Bittencourt PI Jr, McClenaghan NH, Flatt PR, Murphy C, Newsholme P.

J Endocrinol. 2012 Sep;214(3):301-11. Epub 2012 Jul 3.

12.

Differential time course of cytochrome P450 2D6 enzyme inhibition by fluoxetine, sertraline, and paroxetine in healthy volunteers.

Liston HL, DeVane CL, Boulton DW, Risch SC, Markowitz JS, Goldman J.

J Clin Psychopharmacol. 2002 Apr;22(2):169-73.

PMID:
11910262
13.

Immunomodulatory effect of selective serotonin reuptake inhibitors (SSRIs) on human T lymphocyte function and gene expression.

Taler M, Gil-Ad I, Lomnitski L, Korov I, Baharav E, Bar M, Zolokov A, Weizman A.

Eur Neuropsychopharmacol. 2007 Dec;17(12):774-80. Epub 2007 May 14.

PMID:
17499975
14.

The effect of selective serotonin reuptake inhibitors (SSRIs) on the pharmacokinetics and metabolism of perazine in the rat.

Daniel WA, Syrek M, Haduch A, Wójcikowski J.

J Pharm Pharmacol. 2001 Apr;53(4):449-61.

PMID:
11341361
15.

Crucial role of insulin receptor substrate-2 in compensatory beta-cell hyperplasia in response to high fat diet-induced insulin resistance.

Takamoto I, Terauchi Y, Kubota N, Ohsugi M, Ueki K, Kadowaki T.

Diabetes Obes Metab. 2008 Nov;10 Suppl 4:147-56. doi: 10.1111/j.1463-1326.2008.00951.x.

PMID:
18834442
16.
17.

Selective serotonin reuptake inhibitors in affective disorders--I. Basic pharmacology.

Goodnick PJ, Goldstein BJ.

J Psychopharmacol. 1998;12(3 Suppl B):S5-20. Review.

PMID:
9808077
18.

Glucokinase activation ameliorates ER stress-induced apoptosis in pancreatic β-cells.

Shirakawa J, Togashi Y, Sakamoto E, Kaji M, Tajima K, Orime K, Inoue H, Kubota N, Kadowaki T, Terauchi Y.

Diabetes. 2013 Oct;62(10):3448-58. doi: 10.2337/db13-0052. Epub 2013 Jun 25.

19.

Glucose and fatty acids synergize to promote B-cell apoptosis through activation of glycogen synthase kinase 3β independent of JNK activation.

Tanabe K, Liu Y, Hasan SD, Martinez SC, Cras-Méneur C, Welling CM, Bernal-Mizrachi E, Tanizawa Y, Rhodes CJ, Zmuda E, Hai T, Abumrad NA, Permutt MA.

PLoS One. 2011 Apr 26;6(4):e18146. doi: 10.1371/journal.pone.0018146.

20.

Acute effects of selective serotonin reuptake inhibitors on neuroleptic-induced catalepsy in mice.

Pires JG, Bonikovski V, Futuro-Neto HA.

Braz J Med Biol Res. 2005 Dec;38(12):1867-72. Epub 2005 Nov 9.

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