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Items: 1 to 20 of 148

1.

Amiloride attenuates lipopolysaccharide-accelerated atherosclerosis via inhibition of NHE1-dependent endothelial cell apoptosis.

Cui GM, Zhao YX, Zhang NN, Liu ZS, Sun WC, Peng QS.

Acta Pharmacol Sin. 2013 Feb;34(2):231-8. doi: 10.1038/aps.2012.155. Epub 2012 Dec 31.

2.

Probucol via inhibition of NHE1 attenuates LPS-accelerated atherosclerosis and promotes plaque stability in vivo.

Li JF, Chen S, Feng JD, Zhang MY, Liu XX.

Exp Mol Pathol. 2014 Apr;96(2):250-6. doi: 10.1016/j.yexmp.2014.02.010. Epub 2014 Mar 1.

PMID:
24594116
3.

Lipopolysaccharide induces endothelial cell apoptosis via activation of Na(+)/H(+) exchanger 1 and calpain-dependent degradation of Bcl-2.

Zhao Y, Cui G, Zhang N, Liu Z, Sun W, Peng Q.

Biochem Biophys Res Commun. 2012 Oct 12;427(1):125-32. doi: 10.1016/j.bbrc.2012.09.023. Epub 2012 Sep 17.

PMID:
22995319
4.

Suppression of NHE1 by small interfering RNA inhibits HIF-1α-induced angiogenesis in vitro via modulation of calpain activity.

Mo XG, Chen QW, Li XS, Zheng MM, Ke DZ, Deng W, Li GQ, Jiang J, Wu ZQ, Wang L, Wang P, Yang Y, Cao GY.

Microvasc Res. 2011 Mar;81(2):160-8. doi: 10.1016/j.mvr.2010.12.004. Epub 2010 Dec 24.

PMID:
21185840
5.

Na+/H+ exchanger is required for hyperglycaemia-induced endothelial dysfunction via calcium-dependent calpain.

Wang S, Peng Q, Zhang J, Liu L.

Cardiovasc Res. 2008 Nov 1;80(2):255-62. doi: 10.1093/cvr/cvn179. Epub 2008 Jun 30.

PMID:
18591204
6.

Role of NHE1 in calcium signaling and cell proliferation in human CNS pericytes.

Nakamura K, Kamouchi M, Kitazono T, Kuroda J, Matsuo R, Hagiwara N, Ishikawa E, Ooboshi H, Ibayashi S, Iida M.

Am J Physiol Heart Circ Physiol. 2008 Apr;294(4):H1700-7. doi: 10.1152/ajpheart.01203.2007. Epub 2008 Feb 8.

7.

Na+/H+ exchanger mediates TNF-alpha-induced hepatocyte apoptosis via the calpain-dependent degradation of Bcl-xL.

Liu Z, Wang S, Zhou H, Yang Y, Zhang M.

J Gastroenterol Hepatol. 2009 May;24(5):879-85. doi: 10.1111/j.1440-1746.2008.05715.x. Epub 2009 Feb 9.

PMID:
19220664
8.

Amiloride inhibits hydrogen peroxide-induced Ca2+ responses in human CNS pericytes.

Nakamura K, Kamouchi M, Kitazono T, Kuroda J, Shono Y, Hagiwara N, Ago T, Ooboshi H, Ibayashi S, Iida M.

Microvasc Res. 2009 May;77(3):327-34. doi: 10.1016/j.mvr.2008.12.001. Epub 2008 Dec 25.

PMID:
19154746
9.

FRP inhibits ox-LDL-induced endothelial cell apoptosis through an Akt-NF-{kappa}B-Bcl-2 pathway and inhibits endothelial cell apoptosis in an apoE-knockout mouse model.

Liu S, Shen H, Xu M, Liu O, Zhao L, Liu S, Guo Z, Du J.

Am J Physiol Endocrinol Metab. 2010 Sep;299(3):E351-63. doi: 10.1152/ajpendo.00005.2010. Epub 2010 Jun 8.

10.
11.

Expression and modulation of Na(+) /H(+) exchanger 1 gene in hepatocellular carcinoma: A potential therapeutic target.

Yang X, Wang D, Dong W, Song Z, Dou K.

J Gastroenterol Hepatol. 2011 Feb;26(2):364-70. doi: 10.1111/j.1440-1746.2010.06382.x.

PMID:
21261728
12.

Amiloride derivatives induce apoptosis by depleting ER Ca(2+) stores in vascular endothelial cells.

Park KS, Poburko D, Wollheim CB, Demaurex N.

Br J Pharmacol. 2009 Apr;156(8):1296-304. doi: 10.1111/j.1476-5381.2009.00133.x. Epub 2009 Mar 19.

13.

Protective effect of ultrafiltered XinMaiJia extract against H₂O₂-induced injury in human umbilical vein endothelial cells through NHE1 downregulation.

Yin YL, Li P, Yang J, Liu DW, Sun RL, Pan GP, Wan GM, Wan GR.

Genet Mol Res. 2014 Oct 20;13(4):8436-49. doi: 10.4238/2014.October.20.20.

14.

Mechanisms of hypotonic inhibition of the sodium, proton exchanger type 1 (NHE1) in a biliary epithelial cell line (Mz-Cha-1).

Elsing C, Gosch I, Hennings JC, Hübner CA, Herrmann T.

Acta Physiol (Oxf). 2007 Jul;190(3):199-208.

PMID:
17581135
15.

Intracellular Acid-extruding regulators and the effect of lipopolysaccharide in cultured human renal artery smooth muscle cells.

Loh SH, Lee CY, Tsai YT, Shih SJ, Chen LW, Cheng TH, Chang CY, Tsai CS.

PLoS One. 2014 Feb 21;9(2):e90273. doi: 10.1371/journal.pone.0090273. eCollection 2014.

16.

Suppression of Na+/H + exchanger 1 by RNA interference or amiloride inhibits human hepatoma cell line SMMC-7721 cell invasion.

Yang X, Wang D, Dong W, Song Z, Dou K.

Med Oncol. 2011 Mar;28(1):385-90. doi: 10.1007/s12032-010-9447-x. Epub 2010 Feb 12.

PMID:
20151228
17.

Activation of Na+/H+ exchanger 1 is sufficient to generate Ca2+ signals that induce cardiac hypertrophy and heart failure.

Nakamura TY, Iwata Y, Arai Y, Komamura K, Wakabayashi S.

Circ Res. 2008 Oct 10;103(8):891-9. doi: 10.1161/CIRCRESAHA.108.175141. Epub 2008 Sep 5.

18.

[Overexpression of NHE1 suppresses ABCA1 protein expression via increasing calpain activity in RAW264.7 cells].

Mo X, Wang L, Guo J, Hong W, Long S, Zhang L, Xiang N, Yang J.

Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2017 Jan;33(1):12-16. Chinese.

PMID:
28031107
19.

Na(+) /H(+) exchanger 1 (NHE1) function is necessary for maintaining mammary tissue architecture.

Jenkins EC Jr, Debnath S, Varriano S, Gundry S, Fata JE.

Dev Dyn. 2014 Feb;243(2):229-42. doi: 10.1002/dvdy.24032. Epub 2013 Oct 24.

20.

Endothelial Na+/H+ exchanger NHE1 participates in redox-sensitive leukocyte recruitment triggered by methylglyoxal.

Qadri SM, Su Y, Cayabyab FS, Liu L.

Cardiovasc Diabetol. 2014 Sep 30;13:134. doi: 10.1186/s12933-014-0134-7.

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